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Engineering an Escherichia coli chassis strain to produce heterologous antigen-containing outer membrane vesicles for use as a novel mucosal vaccine p

Lead Research Organisation: University of Nottingham
Department Name: School of Life Sciences

Abstract

Hyper-vesiculating E.coli will be engineered to produce outer membrane vesicles (OMVs) containing antigens from Clostridium difficile. These OMVs will be tested for their protective efficacy against C. diff infection in relevant animal models.

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Studentship Projects

Project Reference Relationship Related To Start End Student Name
BB/M008770/1 30/09/2015 31/03/2024
2103848 Studentship BB/M008770/1 30/09/2018 30/12/2022