The molecular recognition and function of the TGFBeta1 - neuropilin interaction: a computational, biophysical and biological study.
Lead Research Organisation:
UNIVERSITY COLLEGE LONDON
Department Name: The Wolfson Inst for Biomedical Research
Abstract
Immune targeting agents are transforming the treatment of cancer. We have identified the TGFBeta1 - NRP1interaction as an important signaling axis in controlling the immune response to tumours. This project works out the details of the molecular interactions for TGFBeta1 - NRP1 using computational, biophysical and cell biology methods. The results will provide fundamental knowledge important in the development of new therapies for cancer.
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ORCID iD |
Studentship Projects
| Project Reference | Relationship | Related To | Start | End | Student Name |
|---|---|---|---|---|---|
| BB/M009513/1 | 30/09/2015 | 31/03/2024 | |||
| 2241836 | Studentship | BB/M009513/1 | 30/09/2019 | 29/09/2023 |