ECG-free and free-breathing cardiac 7T MRI for high resolution applications.
Lead Research Organisation:
University of Oxford
Department Name: RDM Radcliffe Department of Medicine
Abstract
The problem - Parallel transmit is the answer to complex B1 disruption at 7T, but it is too cumbersome and sensitive to cardiac and respiratory changes in B1 and B0. This makes its practical application limited. The goal is to design a system and that makes this process robust and as simple as it is at 3T.
The components I foresee are:
A pulse sequence for B1 - B0 cardio-respiratory resolved mapping. Methods that need to be learned for this are:
Pulse sequence programming - C++
Motion estimation with the scattering matrix
Image reconstruction
Reading - methods for relative B1+ mapping and methods for absolute B1+ mapping - pre-pulse method (a good bet), read on all methods - DREAM, AFI, Bloch Siegert shift, phase sensitive B1+ mapping, infer metric B1+ mapping
Parallel transmit RF pulse design - T1 and T2 prep, excitation
Optimisation,
RF pulse design
Reading: RF pulse design methods: Spokes, kt-points
Pulse sequences
T1 weighted (specifically for late enhancement and perfusion),
T2 prep for 3D cine
The components I foresee are:
A pulse sequence for B1 - B0 cardio-respiratory resolved mapping. Methods that need to be learned for this are:
Pulse sequence programming - C++
Motion estimation with the scattering matrix
Image reconstruction
Reading - methods for relative B1+ mapping and methods for absolute B1+ mapping - pre-pulse method (a good bet), read on all methods - DREAM, AFI, Bloch Siegert shift, phase sensitive B1+ mapping, infer metric B1+ mapping
Parallel transmit RF pulse design - T1 and T2 prep, excitation
Optimisation,
RF pulse design
Reading: RF pulse design methods: Spokes, kt-points
Pulse sequences
T1 weighted (specifically for late enhancement and perfusion),
T2 prep for 3D cine
Studentship Projects
Project Reference | Relationship | Related To | Start | End | Student Name |
---|---|---|---|---|---|
EP/V519741/1 | 01/10/2020 | 30/09/2025 | |||
2432150 | Studentship | EP/V519741/1 | 01/10/2020 | 30/09/2024 | James Kent |