Machine learning approaches for clinical diagnosis of autoimmune diseases
Lead Research Organisation:
University of Liverpool
Department Name: Institute of Translational Medicine
Abstract
Machine learning approaches for clinical diagnosis of autoimmune diseases
Studentship Projects
| Project Reference | Relationship | Related To | Start | End | Student Name |
|---|---|---|---|---|---|
| EP/T517975/1 | 01/10/2020 | 30/09/2025 | |||
| 2439889 | Studentship | EP/T517975/1 | 01/10/2020 | 30/06/2024 | Hannah Kockelbergh |
| Description | Soilleux-Fowler group |
| Organisation | University of Cambridge |
| Department | Department of Pathology |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | My supervisor and I contribute expertise in statistics and machine learning methodology, either undertaking or guiding such analysis of immune repertoire datasets produced by the team at the Universtiy of Cambridge. This includes projects undertaken by students at the University of Cambridge. |
| Collaborator Contribution | The team at the University of Cambridge is led by Professor Elizabeth Soilleux, who is a clinical pathologist. She contributes essential clinical expertise and context to projects that relate to diagnosis, such as my PhD project. The team undertake immune repertoire library preparation for sequencing, which results in immune repertoire datasets with cases and controls for analysis. They also share knowledge about the library preparation and sequencing process which improves the quality of our analysis by influencing how we process the datasets. |
| Impact | We published a review paper together: "Utility of Bulk T-Cell Receptor Repertoire Sequencing Analysis in Understanding Immune Responses to COVID-19." |
| Start Year | 2020 |
| Description | 43rd International Society for Clinical Biostatistics poster |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I presented a digital poster at the conference. The poster was only digital and did not have much reach, but I had some discussions with other postgraduate students. |
| Year(s) Of Engagement Activity | 2022 |
| Description | European Mathematical Genetics Meeting 2022 poster |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I presented a physical poster and engaged in discussion with other researchers, explaining the my research and receiving useful feedback. |
| Year(s) Of Engagement Activity | 2022 |
| Description | North of England Genetic Epidemiology Group meeting short talk |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Postgraduate students |
| Results and Impact | Presented ongoing work on T-cell repertoire feature extraction to statistical geneticists. Discussion followed afterwards where I gave further explanation and received useful suggestions for future development of the methodology. |
| Year(s) Of Engagement Activity | 2022 |