📣 Help Shape the Future of UKRI's Gateway to Research (GtR)

We're improving UKRI's Gateway to Research and are seeking your input! If you would be interested in being interviewed about the improvements we're making and to have your say about how we can make GtR more user-friendly, impactful, and effective for the Research and Innovation community, please email gateway@ukri.org.

An insect model of cognitive decline and extended longevity

Lead Research Organisation: University of Bristol
Department Name: Biochemistry

Abstract

This project combines approaches from evolutionary biology, comparative neuroscience, and ageing research in order to identify mechanisms of extended longevity in the neotropical Heliconius butterflies. Heliconius is a widely studied genus in evolutionary biology, and thus presents a tractable system with many available genomic tools for probing interesting phenotypes. One such interesting phenotype is its extended longevity in comparison with its close relatives, with Heliconius living up to 6 months in the wild - approximately 6 times longer than its closely-related outgroups. This extension in lifespan has been attributed to its pollen-feeding behaviour, unique among butterflies, which provides Heliconius with an adult source of amino acids, and has been linked to a delay in reproductive senescence within the genus. This pollen-feeding behaviour in Heliconius has also been associated with a dramatic expansion of the mushroom body, an insect learning and memory centre, making it an especially intriguing system from a neurobiological perspective.

People

ORCID iD

Publications

10 25 50

Studentship Projects

Project Reference Relationship Related To Start End Student Name
MR/N013794/1 30/09/2016 29/09/2025
2448919 Studentship MR/N013794/1 30/09/2020 01/10/2024