Fluorination of bioactive compounds

Lead Research Organisation: University of Southampton
Department Name: Sch of Chemistry

Abstract

This is a synthetic organic chemistry project, dealing with the synthesis of fluorinated bioactive compounds. The project fits in a larger research program in our group, and the choice of modifications is guided byour recent work in how physical properties of organic molecules can be modified by targeted fluorination, and how these effects can be explained and predicted (key papers: Angew. Chem. Int.Ed.2012, 51, 6176 (VIP); Chem. Eur. J. 2014, 20, 106;J. Am. Chem. Soc.2015, 137, 1230; Chem. Eur. J. 2015, 21, 17808; Angew. Chem. Int. Ed.2015, in press (VIP)).

Publications

10 25 50

Studentship Projects

Project Reference Relationship Related To Start End Student Name
EP/N509747/1 01/10/2016 30/09/2021
2628321 Studentship EP/N509747/1 01/10/2016 30/09/2019 David Evans