The Contribution of Mitochondrial Dysfunction to Alzheimer's disease

Lead Research Organisation: CARDIFF UNIVERSITY
Department Name: School of Medicine

Abstract

Alzheimer's disease (AD) is associated with increased oxidative stress and mitochondrial dysfunction in the brain. The Redox system that helps detoxify neurons is decreased in AD patients and likely contributes to symptoms and neurodegeneration. The PhD student will manipulate Redox and mitochondrial regulating genes in Drosophila and iPSC neuron models of AD to find new potential therapeutic targets.

Publications

10 25 50

Studentship Projects

Project Reference Relationship Related To Start End Student Name
MR/W006308/1 01/10/2022 30/09/2028
2886872 Studentship MR/W006308/1 01/10/2023 30/09/2027 Rhiannan Cummings