Methods development and applications for ultrafast protein crystallography

Lead Research Organisation: Imperial College London
Department Name: Life Sciences

Abstract

Light-activated systems are powerful tools for studying the dynamical response of proteins to
specific external signals. Because the photosensitive response can be initiated with a laser, it can be
followed with high temporal resolution. The van Thor lab has specialized in studying the earliest
events in protein response - i.e. the dynamics that occur between hundreds of femtoseconds and
picoseconds - through ultrafast spectroscopy and ultrafast crystallography.
This PhD will exploit and develop these methods to further characterize the ultrafast dynamical
response in biologically relevant proteins.

Publications

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Studentship Projects

Project Reference Relationship Related To Start End Student Name
EP/R513052/1 01/10/2018 30/09/2023
2900650 Studentship EP/R513052/1 28/09/2019 06/04/2023 Alisa Fadina