Non-Enzymatic Sensing of Creatinine for Early Detection of Chronic Kidney Disease
Lead Research Organisation:
Lancaster University
Department Name: Chemistry
Abstract
In recent years, there has been a dramatic advancement of biochemical markers for kidney healthcare. Creatinine is a useful metabolite for the evaluation of Chronic Kidney Disease (CKD). Creatinine concentrations in urine <3 and >20 mM may indicate CKD. CKD can be detected earlier before the disease has progressed to further stages using a creatinine sensing platform. Early detection and monitoring can provide lifesaving intervention, and as such there is a need to develop rapid, cheap and highly selective electrochemical non-enzymatic creatinine sensors to overcome some of the limitations of state-of-the-art enzymatic creatinine biosensors or the long-established colorimetric Jaffe reaction method. Low cost, non-enzymatic sensing platforms were developed as part of the PhD.
Organisations
People |
ORCID iD |
Sonal Bajpai (Student) | http://orcid.org/0000-0002-7460-8428 |
Studentship Projects
Project Reference | Relationship | Related To | Start | End | Student Name |
---|---|---|---|---|---|
EP/R513076/1 | 01/10/2018 | 30/09/2023 | |||
2903497 | Studentship | EP/R513076/1 | 01/10/2019 | 30/06/2023 | Sonal Bajpai |