Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. (2018)
Attributed to:
The Spatiotemporal Regulation of the Keap1/Nrf2 pathway
funded by
BBSRC
Abstract
No abstract provided
Bibliographic Information
Digital Object Identifier: http://dx.doi.org/10.1038/nature25986
PubMed Identifier: 29590092
Publication URI: http://europepmc.org/abstract/MED/29590092
Type: Journal Article/Review
Volume: 556
Parent Publication: Nature
Issue: 7699
ISSN: 0028-0836