Generation of singlet oxygen mediated by silicon nanoassemblies for novel organic catalytic reactions
Lead Research Organisation:
University of Glasgow
Department Name: School of Chemistry
Abstract
The proposed project is in the area of sustainable chemical technology and is ultimately aimed at developing a novel generic approach towards clean organic synthesis. The methodology, exploiting reactivity of singlet oxygen in diastereo- and enantioselective reactions, will be developed. The proposed methodology is, uniquely, based on the synergy between recently discovered highly effective generation of 1O2, mediated by silicon nanocrystals assemblies, and the novel reaction engineering concept of multifunctional structured reactors with imbedded light-emitting diodes. The proposal identifies the significant potential of adopting new concepts of process intensification (via non-thermal activation and miniaturisation, i.e. enhanced mass and heat transfer) and functional nanomaterials in clean organic catalysis. Most significantly, the proposal addresses the underdevelopments in the areas of clean organic synthesis and non-thermal activation of molecules.
Organisations
Publications
Malkov AV
(2011)
Enantioselective allylation of a,ß-unsaturated aldehydes with allyltrichlorosilane catalyzed by METHOX.
in The Journal of organic chemistry
Malkov AV
(2009)
Enantioselective and catalytic method for alpha-crotylation of aldehydes with a kinetic self-refinement of stereochemistry.
in Chemistry (Weinheim an der Bergstrasse, Germany)
Malkov AV
(2014)
Palladium-catalyzed alkoxycarbonylation of terminal alkenes to produce a,ß-unsaturated esters: the key role of acetonitrile as a ligand.
in Chemistry (Weinheim an der Bergstrasse, Germany)
Malkov AV
(2012)
Stereoselective palladium-catalyzed functionalization of homoallylic alcohols: a convenient synthesis of di- and trisubstituted isoxazolidines and ß-amino-d-hydroxy esters.
in Chemistry (Weinheim an der Bergstrasse, Germany)
Malkov AV
(2014)
Palladium-catalyzed stereoselective intramolecular oxidative amidation of alkenes in the synthesis of 1,3- and 1,4-amino alcohols and 1,3-diamines.
in Chemistry (Weinheim an der Bergstrasse, Germany)
Loponov K
(2014)
Optimization of a Scalable Photochemical Reactor for Reactions with Singlet Oxygen
in Organic Process Research & Development