Sub-second function imaging with MRI: a new window on brain dynamics and its relation to structural connectvity

Lead Research Organisation: King's College London
Department Name: Neuroimaging

Abstract

Collating information

Publications

10 25 50

Studentship Projects

Project Reference Relationship Related To Start End Student Name
MR/N013700/1 01/10/2016 30/09/2025
1856390 Studentship MR/N013700/1 01/10/2016 26/05/2019 Marina Rakic
 
Title An optimising feature in StarTrack software for analysing diffusion MRI data 
Description StarTrack is a program developed in Matlab to analyse diffusion imaging data using DTI, spherical deconvolution (SD) and tractography. At its core, it computes diffusion tensors or fibre orientation distributions (FOD) and performs whole-brain tractography using different algorithms to map the human white matter anatomy. A part of my project was to implement a gradient optimisation method in finding the local maxima of these 3D spherical functions (FODs) within the StarTrack software and assist the implementation of 2 different bootstrapping methods for uncertainty calculations in the analysis. 
Type Of Technology Software 
Year Produced 2018 
Open Source License? Yes  
Impact The optimisation algorithm added to the software allows for for a more precise estimation of the directionality of fibre organization on a sub-voxel level in diffusion MRI data and therefore outputting more precise structural connectivity measures. 
URL https://www.mr-startrack.com/
 
Description Conference presentations (ISMRM 2017, ISMRM 2018, OHBM 2018) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact A talk presentation and poster presentations have been done at 2 different international conferences - International Society for Magnetic Resonance in Medicine (ISMRM) in 2017 and 2018, and Organisation for Human Brain Mapping (OHBM) in 2018. The attendance at the talk was 50-100 people. The questions after the presentations started debated and triggered ideas for future research. Multiple people approached me after the talk to get more information on the results of my research.
Year(s) Of Engagement Activity 2017,2018
URL https://www.humanbrainmapping.org/files/2018/Oral%20Session/Mod%20I.pdf