Studies of spider silk for biotechnology: From natural to synthetic fibres

Lead Research Organisation: University of Nottingham
Department Name: School of Life Sciences

Abstract

Spider silk has many properties that are advantageous to a biomaterial. In addition to having remarkable tensile strength it is also biocompatible, which makes it an interesting candidate for both bioengineering and medical applications. Due to this, and the relative difficulty of farming spiders due to their cannibalistic nature, much interest has focussed on the recombinant production of synthetic spider silk. Optimisation of the design of recombinant silk proteins relies on our understanding not only of what is transcribed, but of translation and assembly of native silk proteins. Understanding the importance of each of these processes will allow a rational design approach to recombinant silks. This project will aim to shed light on the complex genetic regulation of spider silk genes and use this information to create synthetic silk proteins.

Publications

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Studentship Projects

Project Reference Relationship Related To Start End Student Name
BB/M008770/1 01/10/2015 31/03/2024
1944186 Studentship BB/M008770/1 01/10/2017 30/09/2021
 
Description Open Days 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Increased interest in the research and encouraged more students to study research based subjects.
Year(s) Of Engagement Activity 2018,2019,2020
 
Description Pint of Science 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Pint of Science event - linking animals to research and opening up debate about harnessing the power of natural materials in biotechnology.
Year(s) Of Engagement Activity 2019
 
Description University of the Third Age 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Presentation on research area and focus on biotechnological research - leading to more interest in science and research.
Year(s) Of Engagement Activity 2018