Sex differences in Cognitive Performance, Cognitive Decline, and Risk of Dementia: A Lifecourse Approach

Lead Research Organisation: University College London
Department Name: Epidemiology and Public Health

Abstract

Using data from the Whitehall II study, this project has two aims:
1. To investigate sex differences in cognitive performance, rate of cognitive decline, and
risk of dementia, with attention to cohort differences. There is some evidence that sex
differences in cognitive performance have been attenuated in more recent birth-cohorts
due to better access to education (Singh-Manoux 2010). How such differences are
reflected in rate of cognitive decline and risk of dementia is unclear.
2. To examine interactions between sex and risk factors (social, behavioural, and
biological) for their role in differences in cognitive performance, cognitive decline, and
risk of dementia. The study has a wide array of risk factors, listed in the table below.

Publications

10 25 50

Studentship Projects

Project Reference Relationship Related To Start End Student Name
ES/P000592/1 01/10/2017 30/09/2027
2248786 Studentship ES/P000592/1 01/10/2019 11/08/2022 Mikaela Bloomberg