Social, psychological and genetic resilience to adversity in bipolar disorder

Lead Research Organisation: King's College London
Department Name: Social Genetic and Dev Psychiatry Centre

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Publications

10 25 50
 
Description The results of this fellowship covered two themes. First, the fellowship research demonstrated the association between stressful life events and bipolar disorder, including their interaction with genetic factors for bipolar depression. Second, was the link between adversity in childhood and adverse health outcomes in adulthood (e.g., cardiovascular disorder) especially among people with bipolar disorder.
Exploitation Route The outcome of this work highlight the importance of life stress on the course and onset of bipolar disorder and need to target these factors in intervention efforts.
Sectors Healthcare

 
Description Clinical Preceptorship for Consultant Psychiatrists
Geographic Reach National 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Paper included in systematic review
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in systematic reviews
URL http://bmcmedicine.biomedcentral.com/articles/10.1186/1741-7015-12-7
 
Description APPA travel award
Amount $533 (USD)
Organisation National Institutes of Health (NIH) 
Department National Institute on Drug Abuse (NIDA)
Sector Public
Country United States
Start 03/2014 
End 03/2014
 
Description Research Grant
Amount £385,265 (GBP)
Funding ID ES/K00638X/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 01/2014 
End 01/2017
 
Description Collaborations with Prof Antonia Bifulco 
Organisation Middlesex University
Country United Kingdom 
Sector Academic/University 
PI Contribution Georgina Hosang worked with Prof Antonia Bifulco and her team whilst she was an ESRC/MRC Interdisciplinary Postdoctoral Fellow. One of the outcomes of this work was a grant application to continue working together. This application to the ESRC was successful, and the project has been on-going since January 2014.
Collaborator Contribution Prof Antonia Bifulco has led the project with her team at Middlesex University
Impact Although the project is on-going and the data is currently being collected the outputs are limited, however the team have published a paper describing the methodology and the rationale for this approach (see Spence et al., 2015).
Start Year 2012
 
Description Bipolar UK Charity magazine article: Are we genetically sensitive to life stress? 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Patients, carers and/or patient groups
Results and Impact Based on Dr Hosang's research on life events and bipolar disorder an article for the Bipolar UK Charity magazine: Pendulum was written and published in 2012. The aim of the article was to disseminate the findings of research and highlight the importance life stress is for bipolar disorder, a condition which many argue is biologically driven.
Year(s) Of Engagement Activity 2012
 
Description Bipolar disorder and ADHD : why the confusion? 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact Seminar to the Institute of Psychiatry's weekly grand Round Series. Audience includes academics and clinicans (including trainees) alike.
Year(s) Of Engagement Activity 2010
 
Description IBF webinar 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Patients, carers and/or patient groups
Results and Impact This webinar was delivered to members of the International Bipolar Foundation from across the world. Members include patients and their carers as well as practitioners, academics and third sector organisations. The webinar was designed to inform the audience about the role of life stress in bipolar disorder to raise awareness and promote better care for sufferers of the illness.
Year(s) Of Engagement Activity 2014
URL https://vimeo.com/83696649
 
Description Life stress and bipolar disorder 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Other audiences
Results and Impact Lecture delivered to the Psychosis Interest Group at Liverpool University
Year(s) Of Engagement Activity 2012
 
Description Research methods and mental health 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Presented to A-Level students on mental health and how it can be investigated using research methods (using my own work as an example).
Year(s) Of Engagement Activity 2011