Mitochondiral dysfunction and the evolution of brain damage after netional hypoxic-ischaemic insult
Lead Research Organisation:
King's College London
Department Name: Imaging & Biomedical Engineering
Abstract
Aims to:
Explore the effect of HI injury on mitochondrial dynamics
develop small-molecule modulators to maximise mitochondrial function after HI
Explore the effect of HI injury on mitochondrial dynamics
develop small-molecule modulators to maximise mitochondrial function after HI
Organisations
People |
ORCID iD |
| Adam Jones (Student) |
Publications
Faccenda D
(2021)
The ATPase Inhibitory Factor 1 (IF1) regulates the expression of the mitochondrial Ca2+ uniporter (MCU) via the AMPK/CREB pathway.
in Biochimica et biophysica acta. Molecular cell research
Jones A
(2022)
Mitochondrial dynamics in the neonatal brain - a potential target following injury?
in Bioscience reports
Thornton C
(2018)
Mitochondrial dynamics, mitophagy and biogenesis in neonatal hypoxic-ischaemic brain injury.
in FEBS letters
Studentship Projects
| Project Reference | Relationship | Related To | Start | End | Student Name |
|---|---|---|---|---|---|
| MR/N013700/1 | 30/09/2016 | 29/09/2025 | |||
| 1935843 | Studentship | MR/N013700/1 | 30/09/2017 | 29/09/2021 | Adam Jones |