Using metabolomics and tissue imaging to study metabolic interventions in ovarian high-grade serous carcinoma (HGSC).
Lead Research Organisation:
Imperial College London
Department Name: Surgery and Cancer
Abstract
Broadly the aims are
1. To characterise the metabolic response of HGSC to ADI PEG20 (with or without combination treatment) using metabolomics and imaging techniques in in vitro and in vivo studies.
2.To study metabolic response to ADI PEG20 (with or without combination treatment) in clinically relevant genetic backgrounds of HGSC.
3. To develop and optimise methodology and pipelines of analysis for metabolic imaging of in vivo tissues.
1. To characterise the metabolic response of HGSC to ADI PEG20 (with or without combination treatment) using metabolomics and imaging techniques in in vitro and in vivo studies.
2.To study metabolic response to ADI PEG20 (with or without combination treatment) in clinically relevant genetic backgrounds of HGSC.
3. To develop and optimise methodology and pipelines of analysis for metabolic imaging of in vivo tissues.
Organisations
People |
ORCID iD |
| Iain McNeish (Primary Supervisor) |
Studentship Projects
| Project Reference | Relationship | Related To | Start | End | Student Name |
|---|---|---|---|---|---|
| MR/W00710X/1 | 01/10/2022 | 30/09/2028 | |||
| 2749414 | Studentship | MR/W00710X/1 | 03/10/2022 | 30/03/2027 |