Macrophage WNT signalling in liver disease and regeneration
Lead Research Organisation:
University of Edinburgh
Department Name: MRC Centre for Reproductive Health
Abstract
Hypothesis & Aims of the project:
Wnt signalling in macrophages can be modulated to improve tissue repair and reduce tumour load.
AIM 1. To investigate whether macrophage Wnt signalling is required for liver regeneration
AIM 2. To investigate the role of macrophage Wnt signalling in primary tumours and metastasis
AIM 3. To modulate Wnt signalling pathway in order to reprogram macrophages in repair and cancer
Wnt signalling in macrophages can be modulated to improve tissue repair and reduce tumour load.
AIM 1. To investigate whether macrophage Wnt signalling is required for liver regeneration
AIM 2. To investigate the role of macrophage Wnt signalling in primary tumours and metastasis
AIM 3. To modulate Wnt signalling pathway in order to reprogram macrophages in repair and cancer
Organisations
People |
ORCID iD |
| Marta Horcas Lopez (Student) |
Studentship Projects
| Project Reference | Relationship | Related To | Start | End | Student Name |
|---|---|---|---|---|---|
| MR/P502030/1 | 30/09/2016 | 29/09/2022 | |||
| 2815715 | Studentship | MR/P502030/1 | 30/06/2017 | 29/09/2017 | Marta Horcas Lopez |