Molecular assembly using gold catalysis
Lead Research Organisation:
University of St Andrews
Department Name: Chemistry
Abstract
The development of catalytic methods leading to little or no waste is an area of crucial importance in terms of energy and materials economy. The present proposal presents strategies to assemble complex molecular architectures or value-added compounds using simply synthesized organogold complexes. The proposal adopts a two-prong approach. On the one side the design and synthesis of organogold catalysts are proposed and on the other some of the catalysts already synthesized by our group and the novel ones are proposed to enable important chemical transformations. These range from hydration reactions to tandem reactions leading to multiple bond formations in a single step. The aim of the proposal is to develop useful synthetic tools, readily usable by synthetic chemists permitting facile protocols enabling the synthesis of complex molecular assemblies.
Organisations
People |
ORCID iD |
Steven Nolan (Principal Investigator) |
Publications
Gaillard S
(2009)
Synthetic and Structural Studies of [AuCl 3 (NHC)] Complexes
in Organometallics
Ramón R
(2010)
Gold-Catalyzed Meyer-Schuster Rearrangement: Application to the Synthesis of Prostaglandins
in Organometallics
Diebolt O
(2010)
Mixed Phosphite/ N -Heterocyclic Carbene Complexes: Synthesis, Characterization and Catalytic Studies
in Organometallics
Fortman GC
(2010)
A versatile gold synthon for acetylene C-H bond activation.
in Dalton transactions (Cambridge, England : 2003)
Fortman G
(2010)
Solution Calorimetric Study of Ligand Exchange Reactions in the [Au(L)Cl] System (L = Phosphine and Phosphite)
in Organometallics
Nun P
(2010)
Ligand influence in the selective gold-mediated synthesis of allenes.
in Chemical communications (Cambridge, England)
Boogaerts II
(2010)
Carboxylation of C-H bonds using N-heterocyclic carbene gold(I) complexes.
in Journal of the American Chemical Society
Ramón RS
(2010)
Au/Ag-cocatalyzed aldoximes to amides rearrangement under solvent- and acid-free conditions.
in The Journal of organic chemistry
Gaillard S
(2010)
Development of versatile and silver-free protocols for gold(I) catalysis.
in Chemistry (Weinheim an der Bergstrasse, Germany)
Fortman G
(2010)
A Versatile Cuprous Synthon: [Cu(IPr)(OH)] (IPr = 1,3 bis(diisopropylphenyl)imidazol-2-ylidene)
in Organometallics