A complete transcriptional map of the human body: systems biology in toto
Lead Research Organisation:
University of Edinburgh
Department Name: The Roslin Institute
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Publications
Andersson R
(2014)
An atlas of active enhancers across human cell types and tissues.
in Nature
Davis MR
(2014)
Transcriptional profiling of the human fibrillin/LTBP gene family, key regulators of mesenchymal cell functions.
in Molecular genetics and metabolism
De Rie D
(2017)
An integrated expression atlas of miRNAs and their promoters in human and mouse.
in Nature biotechnology
FANTOM Consortium And The RIKEN PMI And CLST (DGT)
(2014)
A promoter-level mammalian expression atlas.
in Nature
Schmidl C
(2014)
Transcription and enhancer profiling in human monocyte subsets.
in Blood
Schroder K
(2012)
Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages.
in Proceedings of the National Academy of Sciences of the United States of America
Shukla R
(2013)
Endogenous retrotransposition activates oncogenic pathways in hepatocellular carcinoma.
in Cell
Summers KM
(2017)
Identification of the macrophage-specific promoter signature in FANTOM5 mouse embryo developmental time course data.
in Journal of leukocyte biology
Description | This award was a travel award to support interactions with the FANTOM Consortium, in Japan. The outcomes provided an unprecedented detail of the way in which human and animal genomes are regulated during development. |
Exploitation Route | The methods developed in this consortium are being applied in our ongoing annotation of multiple livestock species |
Sectors | Agriculture Food and Drink Healthcare |