University of Sheffield – Confidence in Concept 2019
Lead Research Organisation:
University of Sheffield
Department Name: UNLISTED
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Technical Summary
The Confidence in Concept (CIC) scheme is a key part of MRC’s translational research strategy and provides annual awards to institutions to flexibly support a portfolio of early stage translational research projects. CIC is designed to accelerate the transition from discovery research to viable translational projects by supporting preliminary studies to establish proof-of-concept so that the approach will then become competitive for more substantial translational funding.
Publications
Childs C
(2023)
Cutaneous Perfusion Dynamics of the Lower Abdomen in Healthy Normal Weight, Overweight and Obese Women: Methods Development Using Infrared Thermography with Applications for Future Wound Management after Caesarean Section
in International Journal of Environmental Research and Public Health
Giles J
(2022)
A Transfer Learning Algorithm to Reduce Brain-Computer Interface Calibration Time for Long-Term Users
in Frontiers in Neuroergonomics
Mansour S
(2022)
Exploring the ability of stroke survivors in using the contralesional hemisphere to control a brain-computer interface.
in Scientific reports
Ramlakhan S
(2022)
Understanding and interpreting artificial intelligence, machine learning and deep learning in Emergency Medicine.
in Emergency medicine journal : EMJ
Ramlakhan SL
(2022)
Building artificial intelligence and machine learning models : a primer for emergency physicians.
in Emergency medicine journal : EMJ
Shobayo O
(2022)
Infrared Thermal Imaging and Artificial Neural Networks to Screen for Wrist Fractures in Pediatrics
in Technologies
| Description | Regulatory Horizons Council: the regulation of neurotechnology |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| URL | https://www.gov.uk/government/publications/regulatory-horizons-council-the-regulation-of-neurotechno... |
| Description | Research Ethics Training |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Title | Machine learning algorithms for stroke rehabilitation |
| Description | Machine learning algorithms for reducing calibration time and number of electrodes for Brain Computer Interface treatment when used for stroke rehabilitation. |
| Type Of Material | Physiological assessment or outcome measure |
| Year Produced | 2023 |
| Provided To Others? | No |
| Impact | Unknown |
| Title | Secondary Electron Hyperspectral Imaging (SEHI) validation |
| Description | This project aims to reduce the risks and accelerate development of biomaterials for use in the pelvic floor by introducing a new surface imaging technique. We have been able to validate the sensitivity of the SEHI technique by recording its ability to respond to macrophages which become activated to a pro-inflammatory phenotype when cultured on the stretched and oxidised mesh. This has not been achieved before and is only possible because of the extreme sensitivity of the technique. |
| Type Of Material | Biological samples |
| Year Produced | 2023 |
| Provided To Others? | No |
| Impact | Our impact pathway is ongoing. We have developed a collaboration with a group in Germany who have explanted human tissues and are willing to conduct collaborative research. We are preparing a submission to BBSRC to take this work further. |
| Title | In vitro model for biomaterial testing |
| Description | We have developed an in vitro model that could potentially help reduce animal testing of biomaterials. |
| Type Of Material | Computer model/algorithm |
| Year Produced | 2023 |
| Provided To Others? | No |
| Impact | None yet. |
| Description | MRC Confidence in Concept Sheffield Consortium |
| Organisation | Sheffield Children's Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Sheffield provides an excellent translational environment for healthcare research with close collaboration between scientists and clinicians at the University of Sheffield, Sheffield Hallam University, Sheffield Teaching Hospitals NHS Foundation Trust and Sheffield Children's NHS Foundation Trust. The University of Sheffield leads the established Sheffield consortium application to the MRC Confidence in Confidence scheme. The receipt of MRC CiC monies in 2016-2018 has facilitated new collaborations in common areas of research including neuroscience, pain, infection control and medical technologies and all partners involved in projects contributed either financially or in-kind. There is continued strong demand across the partners for funds to accelerate the development of early stage healthcare projects. The Sheffield CiC consortium has established robust and successful processes using external industry experts to rapidly distribute funding and support translation of projects into impact. |
| Collaborator Contribution | Institutional contributions to add value to the funding provided: Reflecting the importance of the MRC CiC scheme to Sheffield, financial contributions to a CiC award was made by TUOS (£80K) and SHU (£30K). Both NHS Foundation Trusts also contribute financially or in-kind up to 10% of the cost of their research activity to projects that they are involved in. TUOS maintains overall administrative responsibility for any potential award, utilises the good practice established in previous CiC rounds and provides significant operational support, overseeing CiC processes, IP arrangements, eligibility, partner contributions, reporting etc which are all captured by formal agreement. This CiC support is augmented by University of Sheffield Knowledge Exchange Commercialisation business managers, many of whom are funded by the Higher Education and Innovation Fund. Our partner institutions similarly support projects they lead on. |
| Impact | All as the full ResearchFish return for this award. |
| Start Year | 2014 |
| Description | MRC Confidence in Concept Sheffield Consortium |
| Organisation | Sheffield Hallam University |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Sheffield provides an excellent translational environment for healthcare research with close collaboration between scientists and clinicians at the University of Sheffield, Sheffield Hallam University, Sheffield Teaching Hospitals NHS Foundation Trust and Sheffield Children's NHS Foundation Trust. The University of Sheffield leads the established Sheffield consortium application to the MRC Confidence in Confidence scheme. The receipt of MRC CiC monies in 2016-2018 has facilitated new collaborations in common areas of research including neuroscience, pain, infection control and medical technologies and all partners involved in projects contributed either financially or in-kind. There is continued strong demand across the partners for funds to accelerate the development of early stage healthcare projects. The Sheffield CiC consortium has established robust and successful processes using external industry experts to rapidly distribute funding and support translation of projects into impact. |
| Collaborator Contribution | Institutional contributions to add value to the funding provided: Reflecting the importance of the MRC CiC scheme to Sheffield, financial contributions to a CiC award was made by TUOS (£80K) and SHU (£30K). Both NHS Foundation Trusts also contribute financially or in-kind up to 10% of the cost of their research activity to projects that they are involved in. TUOS maintains overall administrative responsibility for any potential award, utilises the good practice established in previous CiC rounds and provides significant operational support, overseeing CiC processes, IP arrangements, eligibility, partner contributions, reporting etc which are all captured by formal agreement. This CiC support is augmented by University of Sheffield Knowledge Exchange Commercialisation business managers, many of whom are funded by the Higher Education and Innovation Fund. Our partner institutions similarly support projects they lead on. |
| Impact | All as the full ResearchFish return for this award. |
| Start Year | 2014 |
| Description | MRC Confidence in Concept Sheffield Consortium |
| Organisation | Sheffield Teaching Hospitals NHS Foundation Trust |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Sheffield provides an excellent translational environment for healthcare research with close collaboration between scientists and clinicians at the University of Sheffield, Sheffield Hallam University, Sheffield Teaching Hospitals NHS Foundation Trust and Sheffield Children's NHS Foundation Trust. The University of Sheffield leads the established Sheffield consortium application to the MRC Confidence in Confidence scheme. The receipt of MRC CiC monies in 2016-2018 has facilitated new collaborations in common areas of research including neuroscience, pain, infection control and medical technologies and all partners involved in projects contributed either financially or in-kind. There is continued strong demand across the partners for funds to accelerate the development of early stage healthcare projects. The Sheffield CiC consortium has established robust and successful processes using external industry experts to rapidly distribute funding and support translation of projects into impact. |
| Collaborator Contribution | Institutional contributions to add value to the funding provided: Reflecting the importance of the MRC CiC scheme to Sheffield, financial contributions to a CiC award was made by TUOS (£80K) and SHU (£30K). Both NHS Foundation Trusts also contribute financially or in-kind up to 10% of the cost of their research activity to projects that they are involved in. TUOS maintains overall administrative responsibility for any potential award, utilises the good practice established in previous CiC rounds and provides significant operational support, overseeing CiC processes, IP arrangements, eligibility, partner contributions, reporting etc which are all captured by formal agreement. This CiC support is augmented by University of Sheffield Knowledge Exchange Commercialisation business managers, many of whom are funded by the Higher Education and Innovation Fund. Our partner institutions similarly support projects they lead on. |
| Impact | All as the full ResearchFish return for this award. |
| Start Year | 2014 |