Renewal and Development of the Leeds EPSRC Nanoscience and Nanotechnology Equipment Facility (LENNF)
Lead Research Organisation:
University of Leeds
Department Name: Chemical and Process Engineering
Abstract
This proposal aims to provide significant external access (a total of 140 days over 3 years) to state-of-the-art instrumentation as well as appropriate expertise for nanotechnology researchers specialising in both inorganic nanosystems and also in hybrid inorganic/ organic systems / i.e. bionanotechnology. Accessible facilities will include a synergistic ("one stop shop") combination of inter-related basic techniques for both characterisation and structural and device fabrication: environmental and low voltage scanning electron microscopy (ESEM and LVSEM); atomic force microscopy (AFM); transmission electron microscopy (TEM); X-ray photoelectron spectroscopy (XPS); focused ion beam (FIB) and electron beam lithography (EBL) together with associated cleanroom access. We believe that this integrated analytical approach will ultimately provide a much more productive service both in terms of overall scientific understanding and also productivity, as opposed to the piecemeal provision of many separate specialist activities. We also believe that, as a grouping, we possess the combined experience and facilities to deliver this fully integrated service successfully and efficiently. In addition we would also offer access to some unique specialist facilities such as: a variable temperature, UHV STM: a combined SEM and 4 STM Nanoprober for four point electrical measurements: a combined TEM-STM holder (Nanofactory): a Nanoman virtual reality AFM/ Nanomanipulator: and Magnetic tweezers.
Planned Impact
The provision of funding to support a free-at-point-of-access user facility will ensure a high external utilisation factor for existing, high-value, capital equipment at Leeds, with the income ensuring that this equipment is well supported in terms of staff, and well maintained and upgraded where appropriate. The impact of the investment for UK users would be monitored by an external Steering Committee using a set of key performance indicators and impact would be maximised via our active advertising and outreach campaign targeting, for instance, workshops for DTCs in Nanoscience, Energy, Materials as well as advertising at appropriate conferences. Training events would be continued. The combined facilities would be coordinated actively to attract the best science and that which is most relevant to the RCUK thematic areas, and to act as a "feeder" for larger, more specialised characterisation facilities such as SuperSTEM, NEXUS (XPS), Diamond and ISIS. Hence, the activity will be designed to be complementary to, not competing with, medium scale facilities. To help promote access to its facilities, Leeds has made all its >1000 pieces of equipment (>£25k) externally visible through: https://esms.leeds.ac.uk/, and is currently populating this with technical descriptions/photographs - this will draw additional users into LENFF. The University is also working with regional partners in the N8 to develop methodologies for improved asset sharing.
Publications
Adams SJ
(2014)
Luminescent gold surfaces for sensing and imaging: patterning of transition metal probes.
in ACS applied materials & interfaces
Akhtar M
(2016)
Phase controlled synthesis of copper sulfide nanoparticles by colloidal and non-colloidal methods
in Materials Chemistry and Physics
Alotaibi KM
(2017)
Iron supported on bioinspired green silica for water remediation.
in Chemical science
Bayati M
(2016)
Synthesis and Activity of A Single Active Site N-doped Electro-catalyst for Oxygen Reduction
in Electrochimica Acta
Bear JC
(2014)
Copper-doped CdSe/ZnS quantum dots: controllable photoactivated copper(I) cation storage and release vectors for catalysis.
in Angewandte Chemie (International ed. in English)
Besselink R
(2020)
Mechanism of Saponite Crystallization from a Rapidly Formed Amorphous Intermediate
in Crystal Growth & Design
Brown AR
(2014)
The impact of ? radiation on the bioavailability of Fe(III) minerals for microbial respiration.
in Environmental science & technology
Costa L
(2017)
Liquid-Liquid Interfacial Imaging Using Atomic Force Microscopy
in Advanced Materials Interfaces
Crick C
(2013)
A general method for the incorporation of nanoparticles into superhydrophobic films by aerosol assisted chemical vapour deposition
in Journal of Materials Chemistry A
Description | Original LENNF grant 2008-2013 promoted collaborative research via free at point of use access to specialist equipment and expertise at the University of Leeds: the initial 3.5 years of LENNF led to: a total of 156 (68 unique) users, from > 25 institutions and an allocation of over 400 instrument days; support for over 110 EPSRC grants of facility users; a total of 48 journal publications with users (including the Nature, ACS, J. Phys Chem and Acta groups); a total of 11 joint grant applications with users with specific access costs included; training of ca. 40 Ph.D. students in related DTCs across the UK through student workshops in 2010 & 2011. This continued during the LENNF renewal 2013-2016 with over 40 plus more papers (many more in the pipeline), two further LENNF schools covering > 40 students and many many more external users form across UK academia. The grant has allowed the development of expertise in materials characterisation and has cemented longstanding collaborations with users. |
Exploitation Route | It depends on individual user |
Sectors | Aerospace Defence and Marine Chemicals Digital/Communication/Information Technologies (including Software) Electronics Energy Environment Healthcare Manufacturing including Industrial Biotechology Culture Heritage Museums and Collections Pharmaceuticals and Medical Biotechnology Transport |
URL | http://www.nanotechnology.leeds.ac.uk/lennf/ |
Description | The original LENNF grant has a good track record of promoting collaborative research: the initial 3.5 years of LENNF led to: a total of 156 (68 unique) users, from > 25 institutions and an allocation of over 400 instrument days; support for over 110 EPSRC grants of facility users; a total of 48 journal publications with users (including the Nature, ACS, J. Phys Chem and Acta groups); a total of 11 joint grant applications with users with specific access costs included; training of ca. 40 Ph.D. students in related DTCs across the UK through student workshops in 2010 & 2011. This continued during the LENNF renewal 2013-2016 with over 40 plus more papers (many more in the pipeline), two further LENNF schools covering > 40 students and many many more external users form across UK academia. Following the end of the grant, many collaborators continued to use the facility and we covered some of this usage with some Sir Henry Royce Institute recurrent funding in 2017/18. In late 2017 we submitted a successful proposal to the EPSRC equipment sharing scheme which has awarded a further 2 years of funding for access to Electron Microscopy, XPS and Cleanroom activities under the LENNF umbrella. This new grant (EP/R02863X/1) commenced in 2018 and finished in 2020. Overall the LENNF scheme has provided £1.4M of external access to >200 users since 2008, with a further £15k pa of pump-priming access via Royce Institute recurrent funding between April 2019-2020. |
First Year Of Impact | 2008 |
Sector | Aerospace, Defence and Marine,Agriculture, Food and Drink,Chemicals,Construction,Digital/Communication/Information Technologies (including Software),Electronics,Energy,Environment,Healthcare,Manufacturing, including Industrial Biotechology,Culture, Heritage, Museums and Collections,Pharmaceuticals and Medical Biotechnology,Transport |
Impact Types | Societal Economic |
Description | 3D Nanoscale chemical analysis: a FIBSEM-SIMS facility optimised for soft and composite materials |
Amount | £1,726,123 (GBP) |
Funding ID | EP/V028855/1 |
Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
Sector | Public |
Country | United Kingdom |
Start | 06/2021 |
End | 06/2025 |
Description | Cryogenic electron microscopy for native state analysis of nanoparticles in liquids |
Amount | £196,879 (GBP) |
Funding ID | EP/R043388/1 |
Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
Sector | Public |
Country | United Kingdom |
Start | 08/2018 |
End | 02/2021 |
Description | The Leeds EPSRC Nanoscience and Nanoequipment User Facility |
Amount | £201,946 (GBP) |
Funding ID | EP/R02863X/1 |
Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
Sector | Public |
Country | United Kingdom |
Start | 05/2018 |
End | 11/2021 |
Title | Data associated with 'Liquid-liquid interfacial imaging using atomic force microscopy' |
Description | Dataset associated with the publication "Effect of heparin and heparan sulphate on open promoter complex formation for a simple tandem gene model system using ex-situ atomic force microscopy". The dataset includes the raw AFM images and statistical analysis. It is divided into six parts associated with the following AFM imaging data collected on: 1) cleaved mica; 2) polysaccharide heparin deposited on mica; 3) polysaccharide heparan sulphate deposited on mica; 4) the DNA template with and without the polysaccharides; 5) RNA polymerase with and without the polysaccharides; 6) Open promoter complexes with and without the polysaccharides. |
Type Of Material | Database/Collection of data |
Year Produced | 2017 |
Provided To Others? | Yes |
Description | Quorum Cryo-liftout |
Organisation | Quorum Review- Independent Review Board |
Country | United States |
Sector | Private |
PI Contribution | Collaboration with company Quorum on in-situ liftout of frozen TEM samples |
Collaborator Contribution | Collaboration with company Quorum on in-situ liftout of frozen TEM samples |
Impact | none so far |
Start Year | 2017 |
Description | Annual Royal Microscopical Society School in Elecron Microscopy - every Spring or Summer 2008 onwards |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Postgraduate students |
Results and Impact | Week long Training School for users of the technique |
Year(s) Of Engagement Activity | 2008,2009,2010,2011,2012,2013,2014,2015,2016,2017,2018,2019,2020,2021 |
Description | BBC Radio 4 interview |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | Interview on Nanogold on BBC Radio 4 Inside Science Broadcast 5 March at 16.30 GMT |
Year(s) Of Engagement Activity | 2020 |
URL | https://www.bbc.co.uk/programmes/m000fw1n |
Description | Be Curious Science Outreach event |
Form Of Engagement Activity | Participation in an open day or visit at my research institution |
Part Of Official Scheme? | No |
Geographic Reach | Regional |
Primary Audience | Schools |
Results and Impact | Microscopy Talk, Activities and Display at Be Curious Festival at University of Leeds, Annual event every March |
Year(s) Of Engagement Activity | 2016,2017,2018,2019,2020 |
URL | http://www.leeds.ac.uk/info/4000/around_campus/460/be_curious_festival-about_leeds_and_yorkshire |
Description | Co-organisation of Royal Society Discussion Meeting, Dynamic in-situ microscopy relating structure and function |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Fast-track discussion meeting organised by Dame Pratibha Gai FREng FRS, Professor Edward Boyes, Professor Rik Brydson and Professor Richard Catlow FRS. October 21-22 2019 This meeting evidenced and advanced development in dynamic in-situ environmental electron, scanning probe, optical and fast time resolved microscopy and computer modelling studies of vital interest in the chemical, physical and life sciences, underpinning technologies of high commercial and societal value. It focused on the pivotal role of imaging and spectroscopy for dynamic processes across the sciences to access previously invisible aspects of real world processes. An accompanying journal issue for this meeting was published in Philosophical Transactions of the Royal Society A. |
Year(s) Of Engagement Activity | 2019 |
URL | https://royalsociety.org/science-events-and-lectures/2019/10/in-situ-microscopy/ |
Description | Royce Institute Workshop for PhD students |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Postgraduate students |
Results and Impact | A three day residential workshop for 15-20 PhD students, particularly targeted at those in CDTs, to showcase (mostly) Royce facilities at Leeds. Basic structure was lectures then demonstrations. |
Year(s) Of Engagement Activity | 2020 |
Description | Scientific Organisation of Microscience Microscience Microscopy Congresses MMC2013, 2015, 2017, 2019, 2021 |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Attendance and presentation at conferences |
Year(s) Of Engagement Activity | 2013,2015,2017,2019,2021 |
URL | https://www.mmc-series.org.uk/ |