Constructive lifecycle assessment: implementing a responsible research and innovation approach for synthetic biology
Lead Research Organisation:
University of Manchester
Department Name: Alliance Manchester Business School
Abstract
The doctoral research will explore the sustainability implications of innovation in biotechnology, specifically the case of synthetic biology products. The research focus will be on developing and testing a constructive and anticipatory approach to the assessment of synthetic biology application building on life cycle assessments (LCA). LCA is already widely used to assess environmental impacts throughout all stages of a product's life. However, the anticipatory application of LCA to emerging technologies in order to inform innovation policies and strategies, is a relatively novel approach. This approach would go beyond anticipatory LCA to also consider the wide range of societal, technical and environmental aspects of synthetic biology necessary for achieving responsible research and innovation (RRI) in the field. Drawing on multi-stakeholder reflection and deliberation, the research would explore the interplay between these aspects and how they can be integrated to inform governance and decision-making in synthetic biology, culminating with the development of a framework for constructive LCA. The research would build on research previously funded by EPSRC developing LCA frameworks for emerging technologies.
Organisations
People |
ORCID iD |
Philip Shapira (Primary Supervisor) | |
Nicholas Matthews (Student) |
Publications
Matthews N
(2019)
The role of charitable funding in university research
in Science and Public Policy
Matthews NE
(2019)
Aligning sustainability assessment with responsible research and innovation: Towards a framework for Constructive Sustainability Assessment.
in Sustainable production and consumption
Matthews NE
(2019)
Chromatin Architecture in the Fly: Living without CTCF/Cohesin Loop Extrusion?: Alternating Chromatin States Provide a Basis for Domain Architecture in Drosophila.
in BioEssays : news and reviews in molecular, cellular and developmental biology
Matthews NE
(2019)
Collaborating constructively for sustainable biotechnology.
in Scientific reports
Studentship Projects
Project Reference | Relationship | Related To | Start | End | Student Name |
---|---|---|---|---|---|
EP/N509565/1 | 30/09/2016 | 29/09/2021 | |||
1885346 | Studentship | EP/N509565/1 | 30/09/2017 | 30/03/2021 | Nicholas Matthews |
Description | We have developed and published a framework for constructive sustainability assessment (CSA) which aims to help innovators working on emerging technologies to integrate sustainability considerations into their work. This framework has been applied in practice in a research establishment and a leading synthetic biology company. Both organisations have benefitted from the application of the framework and we have also published another literature article reporting on the process and results of applying CSA in the company. In addition, we have gathered data concerning the challenges and opportunities for innovators trying to integrate sustainability considerations into their operations and plan to publish on this also. |
Exploitation Route | We hope that the individuals who have been engaged with the research, primarily innovators in the field synthetic biology in academic and industry contexts, will take forward the lessons learned from the constructive sustainability assessment processes we have implemented with them. We also hope that they will continue to embed sustainability considerations into their work. |
Sectors | Manufacturing including Industrial Biotechology |
URL | https://www.research.manchester.ac.uk/portal/n.matthews.html |
Description | Through this research we have worked directly with companies and academic researchers involved in developing the field of synthetic biology. We have undertaken sustainability assessments and run workshops with these innovators to help them to understand the sustainability implications of their work and how they might be able to integrate this understanding into their development processes. We hope that this will result in more sustainable outcomes from synthetic biology. |
First Year Of Impact | 2018 |
Sector | Manufacturing, including Industrial Biotechology |
Impact Types | Societal |
Title | SustAssessR |
Description | An integrated codebase for sustainability assessment using R |
Type Of Technology | Software |
Year Produced | 2019 |
Open Source License? | Yes |
Impact | This codebase was used for and is made available alongside the following publication: Matthews, N. E., Cizauskas, C. A., Layton, D. S., Stamford, L., & Shapira, P. (2019). Collaborating constructively for sustainable biotechnology. Scientific Reports. https://doi.org/10.1038/s41598-019-54331-7 |
URL | https://doi.org/10.5281/zenodo.3560207 |