EzMol and BioBlox: Assessing the commercial opportunities and societal benefits of protein modelling resources in industry, schools and museums
Lead Research Organisation:
Imperial College London
Department Name: Life Sciences
Abstract
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Organisations
People |
ORCID iD |
| Michael Sternberg (Principal Investigator) |
| Description | This grant supported a market survey into the viability and strategy to translate the web-based molecular graphics program EzMol and the protein docking games BioBlox into either commercial and/or educational resources. |
| Exploitation Route | Private report |
| Sectors | Agriculture Food and Drink Creative Economy Digital/Communication/Information Technologies (including Software) Education Manufacturing including Industrial Biotechology Pharmaceuticals and Medical Biotechnology |
| Description | Development and marketing of protein docking games for the educational sector |
| Amount | £200,844 (GBP) |
| Funding ID | BB/R01955X/1 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2018 |
| End | 09/2019 |
| Title | BioBlox2.5 |
| Description | This is a game to dock ligands into proteins. Itis availablefrom Google Play and can be played on line. |
| Type Of Technology | Webtool/Application |
| Year Produced | 2019 |
| Impact | Not known |
| URL | http://www.bioblox.org/ |
| Title | BioBlox2D |
| Description | a computer game modelling protein/ligand docking. A fun to play game with an educational component |
| Type Of Technology | Webtool/Application |
| Year Produced | 2017 |
| Impact | Available for mobile devices on App Store and Google play |
| URL | http://www.bioblox.org |
| Title | BioBlox3D |
| Description | A web-based serious computer game to dock proteins. |
| Type Of Technology | Webtool/Application |
| Year Produced | 2017 |
| Impact | Public engagement via users of the game |
| URL | http://www.bioblox3d.org |
| Title | BioBloxVR |
| Description | A virtual reality tool to explore protein/protein docking |
| Type Of Technology | Webtool/Application |
| Year Produced | 2017 |
| Impact | Software used at outreach events to engage public with science. Also used to direct public to play BioBlox2D and BioBlox3D. |
| URL | http://www.bioblox.org |
| Title | EzMol - a web-based wizard-driven program for the display of protein and nucleic acid structures |
| Description | A very simple-to-use web-based molecular visualisation tool developed by our group. It works via most browsers and is driven by a wizard interface. The program is web-based and works with most common browsers so there is no need for any installation or a licence. It is driven a wizard that directs the user through a focussed set of options with no need for any commands to be typed. It supports cartoon, stick and space-filling visualisation options for the protein chains, and the user selects residues for display, colouring and labelling from a presented list, similar to date selection tools on many web sites. The final visualisation model can be downloaded for publication or saved for subsequent use. The interface is particularly designed for the occasional user who does not want to remember command syntax or have to cope with a large number of menu options. Available at http://www.sbg.bio.ic.ac.uk/~ezmol/ |
| Type Of Technology | Webtool/Application |
| Year Produced | 2018 |
| Impact | None yet as just launched |
| URL | http://www.sbg.bio.ic.ac.uk/~ezmol/ |
| Description | Imperial Festival |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | We presented protein modelling. In 2016 and 2017 we also presented the protein docking game BioBlox. |
| Year(s) Of Engagement Activity | 2014,2016,2017 |
| Description | New Scientist Live - stand presentation |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Over 300 visitors to the stand saw protein modelling. |
| Year(s) Of Engagement Activity | 2016,2017 |
| URL | https://live.newscientist.com/ |
| Description | Presentation of protein modelling resources at the Bett - An Educational show at Excel |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Prof Sternberg group together with members of Goldsmiths College exhibited at the Bett Show at the Excel Centre (23-26 January 2019) presenting molecular resources for educational use in schools. Two resources were presented i) EzMol: a web-based program to display protein and nucleic acid structures linked to a teaching portal and ii) BioBlox2D: a mobile game based on docking shapes linked to an A-level syllabus quiz. Imperial issued a press release about these resources. As a result discussion have started with educational tools providers. |
| Year(s) Of Engagement Activity | 2019 |