Prevention & Control of Infectious Diseases: Understanding the basis of host resistance
Lead Research Organisation:
University of Edinburgh
Department Name: The Roslin Institute
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Technical Summary
This programme will reduce the burden of infectious diseases of farmed animals and zoonoses by dissecting host genetic contributions to resistance, resilience and transmission.
Planned Impact
unavailable
Organisations
- University of Edinburgh (Lead Research Organisation)
- Animal and Plant Health Agency (Collaboration)
- Genus plc (Collaboration)
- WorldFish (Collaboration)
- Cobb Vantress (Collaboration)
- Hendrix Genetics (Collaboration)
- International Livestock Research Institute (ILRI) (Collaboration)
- Zoetis (Collaboration)
- Friedrich Loeffler Institute (Collaboration)
- Scotland's Rural College (Collaboration)
- Bill & Melinda Gates Foundation (Collaboration)
- Oxitec Ltd (Collaboration)
Publications
Anagnostopoulos A
(2024)
Association between a genetic index for digital dermatitis resistance and the presence of digital dermatitis, heel horn erosion and interdigital hyperplasia in Holstein cows.
in Journal of dairy science
Chase-Topping M
(2023)
The WUR0000125 PRRS resilience SNP had no apparent effect on pigs' infectivity and susceptibility in a novel transmission trial
in Genetics Selection Evolution
Doeschl-Wilson A
(2023)
Evolutionary Dynamics of the Highly Recombinant Avian Coronavirus, Infectious Bronchitis Virus
in SSRN Electronic Journal
Fraslin C
(2023)
Potential of low-density genotype imputation for cost-efficient genomic selection for resistance to Flavobacterium columnare in rainbow trout (Oncorhynchus mykiss).
in Genetics, selection, evolution : GSE
Ghaderi Zefreh M
(2023)
Exploring the value of genomic predictions to simultaneously improve production potential and resilience of farmed animals.
in Frontiers in genetics
Houaga I
(2023)
Livestock phenomics and genetic evaluation approaches in Africa: current state and future perspectives.
in Frontiers in genetics
Ichikawa K
(2024)
Innovations in poultry reproduction using cryopreserved avian germ cells.
in Reproduction in domestic animals = Zuchthygiene
Idoko-Akoh A
(2023)
Creating resistance to avian influenza infection through genome editing of the ANP32 gene family.
in Nature communications
Kartsonaki C
(2023)
Characteristics and outcomes of an international cohort of 600 000 hospitalized patients with COVID-19
in International Journal of Epidemiology
Matika O
(2023)
Investigating volatile semiochemical production from Bos taurus and Bos indicus as a novel phenotype for breeding host resistance to ixodid ticks.
in Ticks and tick-borne diseases
| Description | EU H2020 collaborative project ECO-READY- Achieving Ecological Resilient Dynamisms for the European food system through consumer-driven policies, socio-ecological challenges, biodiversity, data-driven policy, sustainable futures |
| Amount | € 14,948,450 (EUR) |
| Funding ID | 101084201 - ECO-READY |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | 12/2022 |
| End | 11/2025 |
| Description | New social phenotypes from automated computer vision systems for reducing harmful social interactions and disease transmission in pigs through selective breeding |
| Amount | £54,900 (GBP) |
| Funding ID | BBSRC IAA PIII108 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2023 |
| End | 10/2023 |
| Description | TRAnsforming the DEbate about livestock systems transformation (TRADE) |
| Amount | £677,397 (GBP) |
| Funding ID | BB/W018152/1 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2022 |
| End | 05/2025 |
| Description | roslin foundation phd studentships-rf2023/001 |
| Amount | £560,000 (GBP) |
| Organisation | The Roslin Foundation |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 09/2023 |
| End | 09/2027 |
| Title | Single cell sequencing |
| Description | Highly reliable single cell or nucleus sequencing using 10X Genomics or Parse Biosciences Platform, available to researchers at the University of Edinburgh and externally through a Genomics Facility established at the Roslin Institute. |
| Type Of Material | Technology assay or reagent |
| Year Produced | 2022 |
| Provided To Others? | Yes |
| Impact | Since we established the Genomics Facility at the Roslin Institute, we have enabled approximately 20 different research groups to uptake transformative single cell sequencing technologies in their research, including a range of model and non model species (to date: human, mouse, pig, chicken, sheep, cattle, Atlantic salmon, oyster, shrimp, dog, zebrafish, medaka, among others). |
| URL | https://www.ed.ac.uk/roslin/facilities-resources/genomics-platform |
| Description | Centre for Tropical Livestock Genetics & Health |
| Organisation | Bill and Melinda Gates Foundation |
| Country | United States |
| Sector | Charity/Non Profit |
| PI Contribution | We recently renewed $10M investment from the Bill & Melinda Gates Foundation to sustain the Centre for Tropical Livestock Genetics & Health to 2027. CTLGH involves collaboration between The Roslin Institute, ILRI and SRUC and aims to drive genetic gain in poultry and cattle indigenous to sub-Saharan Africa. It involves contributions from researchers funded by this programme and adds significant value to its objectives. |
| Collaborator Contribution | Collaborative research. |
| Impact | Significant progress is being made in dissecting the genomic architecture of production and health traits in farmed animals indigenous to sub-Saharan Africa, as well as the basis of adaptation to different environments. This will inform the design of breeding strategies that aim to bring lasting genetic improvements. |
| Start Year | 2015 |
| Description | Centre for Tropical Livestock Genetics & Health |
| Organisation | International Livestock Research Institute (ILRI) |
| Country | Kenya |
| Sector | Charity/Non Profit |
| PI Contribution | We recently renewed $10M investment from the Bill & Melinda Gates Foundation to sustain the Centre for Tropical Livestock Genetics & Health to 2027. CTLGH involves collaboration between The Roslin Institute, ILRI and SRUC and aims to drive genetic gain in poultry and cattle indigenous to sub-Saharan Africa. It involves contributions from researchers funded by this programme and adds significant value to its objectives. |
| Collaborator Contribution | Collaborative research. |
| Impact | Significant progress is being made in dissecting the genomic architecture of production and health traits in farmed animals indigenous to sub-Saharan Africa, as well as the basis of adaptation to different environments. This will inform the design of breeding strategies that aim to bring lasting genetic improvements. |
| Start Year | 2015 |
| Description | Centre for Tropical Livestock Genetics & Health |
| Organisation | Scotland's Rural College |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | We recently renewed $10M investment from the Bill & Melinda Gates Foundation to sustain the Centre for Tropical Livestock Genetics & Health to 2027. CTLGH involves collaboration between The Roslin Institute, ILRI and SRUC and aims to drive genetic gain in poultry and cattle indigenous to sub-Saharan Africa. It involves contributions from researchers funded by this programme and adds significant value to its objectives. |
| Collaborator Contribution | Collaborative research. |
| Impact | Significant progress is being made in dissecting the genomic architecture of production and health traits in farmed animals indigenous to sub-Saharan Africa, as well as the basis of adaptation to different environments. This will inform the design of breeding strategies that aim to bring lasting genetic improvements. |
| Start Year | 2015 |
| Description | Development and evaluation of sterile ticks for control of vector-borne diseases. |
| Organisation | Oxitec Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | We are working with Oxitec to genetically alter Rhipicephalus ticks that transmit Theileria, the causative agent of East Coast Fever in cattle in sub-Saharan Africa. The aim is to render ticks sterile, such that when introduced into populations it causes reproductive failure and collapse of tick numbers. |
| Collaborator Contribution | Oxitec contribute their expertise in genetic modification of insects and staff will be located in laboratories close to the Institute. They provide significant funding for studies that interact modified ticks with cattle at a high level of biosecurity. |
| Impact | Ongoing. |
| Start Year | 2023 |
| Description | Editing for Classical Swine Fever resistance in pigs |
| Organisation | Genus plc |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Editing of a candidate gene for resistance to Classical Swine Fever in pigs (target confidential). This was supported partly by a £30k award from the BBSRC Impact Accelerator Account to the Institute and University of Edinburgh in 2023. |
| Collaborator Contribution | Confidential. |
| Impact | Ongoing. |
| Start Year | 2020 |
| Description | Evaluation of edits for Classical Swine Fever Resistance in pigs |
| Organisation | Animal and Plant Health Agency |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Provision of genome-edited pig cells to APHA. |
| Collaborator Contribution | Testing the impact of specific mutations on resistance to Classical Swine Fever Virus. |
| Impact | Ongoing. |
| Start Year | 2023 |
| Description | Genome editing trout for resistance to infectious pancreatic necrosis |
| Organisation | Hendrix Genetics |
| Country | Netherlands |
| Sector | Private |
| PI Contribution | Editing of NAE1 in rainbow trout to determine if this confers resistance to infectious pancreatic necrosis virus. |
| Collaborator Contribution | Hendrix provided the funding for this project (confidential). This was supplemented by £30k from the BBSRC Impact Accelerator Award to the Institute and University of Edinburgh in 2023. Editing and challenge performed via a contract with the Centre for Aquaculture Technologies in Canada. |
| Impact | Ongoing. |
| Start Year | 2020 |
| Description | Genome-scale mutagenesis to identify host genes required for African Swine Fever Virus replication |
| Organisation | Genus plc |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | We plan a genome-wide sgRNA:Cas9 mutagenesis screen to identify host genes required for replication of African Swine Fever Virus in pig macrophages. |
| Collaborator Contribution | Confidential. |
| Impact | Ongoing. |
| Start Year | 2023 |
| Description | Genome-scale mutagenesis to identify host genes required for influenza virus replication |
| Organisation | Cobb Vantress |
| Country | United States |
| Sector | Private |
| PI Contribution | Genome-wide sgRNA:Cas9 screen for avian genes required for replication of influenza A virus. |
| Collaborator Contribution | Provision of funding (confidential). |
| Impact | Ongoing. |
| Start Year | 2020 |
| Description | Genomic selection for resistance to viral aquatic diseases. |
| Organisation | Worldfish |
| Country | Malaysia |
| Sector | Charity/Non Profit |
| PI Contribution | We have partnered with WorldFish, a CGIAR organisation, to study the genomic architecture of resistance of aquatic species to viral diseases. A major recent achievement was the identification of a major quantitative trait locus underlying resistance of Nile tilapia to tilapia lake virus, which can devastate aquaculture systems in low- and middle-income countries (https://pubmed.ncbi.nlm.nih.gov/34262170/). We are working with WorldFish to further understand the basis of resistance and to inform selective breeding strategies to instil resistance into farmed tilapia populations. |
| Collaborator Contribution | Funding and access to resources and expertise. |
| Impact | Ongoing. Once implemented, TilV resistant tilapia are likely to achieve significant societal and economic benefits, particularly for low- and middle-income countries. |
| Start Year | 2020 |
| Description | Identification of candidate genes associated with resistance to African Swine Fever Virus. |
| Organisation | Friedrich Loeffler Institute |
| Country | Germany |
| Sector | Academic/University |
| PI Contribution | We collaborated with FLI to conduct a genome-wide mutagenesis screen for pig genes influencing replication of African Swine Fever Virus (https://pubmed.ncbi.nlm.nih.gov/37604847/). We have sought to protect aspects of the Intellectual Property. |
| Collaborator Contribution | Collaborative research (https://pubmed.ncbi.nlm.nih.gov/37604847/). |
| Impact | We are exploring options to fund the generation of edited pigs to establish the role of candidate genes in ASFV resistance. |
| Start Year | 2021 |
| Description | Option to licence Intellectual Property related to a genome edit that confers resistance to African Swine Fever Virus |
| Organisation | Genus plc |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | This relates to a joint discovery made in this theme of the programme in 2023: Pannhorst K, Carlson J, Hölper JE, Grey F, Baillie JK, Höper D, Wöhnke E, Franzke K, Karger A, Fuchs W, Mettenleiter TC. 2023. The non-classical major histocompatibility complex II protein SLA-DM is crucial for African swine fever virus replication. Sci Rep. 13:10342. doi: 10.1038/s41598-023-36788-9. |
| Collaborator Contribution | Confidential. |
| Impact | Ongoing. |
| Start Year | 2022 |
| Description | Understanding resistance to viral diseases in fish. |
| Organisation | Zoetis |
| Country | United States |
| Sector | Private |
| PI Contribution | With an iCASE studentship funded by the BBSRC we have partnered with Zoetis to understand genetic and immunological factors contributing to the resistance of fish to viral diseases. |
| Collaborator Contribution | Funding and in-kind support. The project is envisaged to include a placement by the doctoral student with Zoetis. |
| Impact | Ongoing. |
| Start Year | 2023 |
| Description | "Oysters in Edinburgh" at Edinburgh Science Festival 2024 (food, drink and science event) |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Evening event for adults at the 2024 Edinburgh Science Festival, combining talks on RI research in oyster biology/natural history, genetics, disease resistance, native oyster conservation projects, social history of oysters in Edinburgh, food (five types of oysters) and matching drinks, with small group discussions and audience Q&A. Supported by RI oyster scientists and PE team. |
| Year(s) Of Engagement Activity | 2023 |
| Description | A paper-based PCR simulation activity |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Schools |
| Results and Impact | A paper-based PCR simulation activity to reinforce how PCR works aimed at S6 secondary school pupils, college students and their teachers |
| Year(s) Of Engagement Activity | 2023,2024 |
| Description | DNA & the Genome | PCR Masterclass: A Question of Taste. A full-day PCR workshop |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Schools |
| Results and Impact | A full-day PCR workshop that aims to engage and inspire final and penultimate high school biology pupils, giving them the opportunity to work with real lab equipment and reagents, supported by RI academic/scientific staff and PGRs, who also discuss their own research and career paths. |
| Year(s) Of Engagement Activity | 2024 |
| Description | Gel Electrophoresis Wall Tank. A classroom resource to support teachers to explore how gel electrophoresis works with their pupils. |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Schools |
| Results and Impact | A classroom resource to support teachers to explore how gel electrophoresis works with their pupils. |
| Year(s) Of Engagement Activity | 2023,2024 |
| Description | Invited Departmental Seminar: "All things fish: genomic perspectives from food security to evolution". |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | Invited Departmental Seminar: Trinity College Dublin (Smurfit Institute of Genetics). 12th Jan 2024. Hosted by Prof. Aoife McLysaght |
| Year(s) Of Engagement Activity | 2024 |
| Description | Invited Lecture: Functional annotation of fish genomes: towards precision aquaculture breeding founded on biological understanding |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited online lecture -'Functional annotation of fish genomes: towards precision aquaculture breeding founded on biological understanding' at the 1st aquaculture seed industry professional forum. 30th China Beijing seed Industry Conference. 11th Sept 2023. Provided audience with overview of latest status of genomic technologies for aquaculture breeding. |
| Year(s) Of Engagement Activity | 2023 |
| Description | Invited Webinar: 'Functional annotation of fish genomes: towards more precise breeding in aquaculture' |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited talk at the 2023 (Qingdao) Conference on International Cooperation for Future Production, Education, Research and Application of the Ocean Industry. Provided audience with overview of latest status of genomic technologies for aquaculture breeding. |
| Year(s) Of Engagement Activity | 2023 |
| Description | Invited Webinar: 'Harnessing single cell transcriptomics to understand and improve salmon performance and health'. Webinar: Understanding and improving salmon performance. Blue Economy Cooperative Research Centre. 21st June 2023. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Invited webinar: 'Harnessing single cell transcriptomics to understand and improve salmon performance and health'. Webinar: Understanding and improving salmon performance. Blue Economy Cooperative Research Centre. 21st June 2023. Provided an overview of the transformative potential of single cell transcriptomic technologies to understanding and improve the welfare, health and performance of farmed salmon. |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://blueeconomycrc.com.au/webinar-understanding-and-improving-salmon-performance/ |
| Description | Invited talk: "AQUA-FAANG: decoding genome function to enhance genotype-to-phenotype prediction in farmed finfish" EAAP Session - EuroFAANG: Genotype-to-phenotype research across Europe and beyond. 31.08.2023, Lyon, France |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Invited talk: "AQUA-FAANG: decoding genome function to enhance genotype-to-phenotype prediction in farmed finfish" EAAP Session - EuroFAANG: Genotype-to-phenotype research across Europe and beyond. 31.08.2023, Lyon, France. Part of a session that included an industry panel session -"How European animal breeding sector can use EuroFAANG Research Infrastructure and knowledge developed so far" Opportunities and barriers for uptaking the results, with 4 panellists coming from industry. |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.gene-switch.eu/uploads/1/2/6/6/126678735/agenda_-_eurofaang_eaap_2025.pdf |
| Description | Lab Techniques: Gel Electrophoresis in Action. Video designed to support Higher Biology and Higher Human Biology learners to develop their knowledge and understanding of PCR. |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Schools |
| Results and Impact | This video has been designed to support Higher Biology and Higher Human Biology learners to develop their knowledge and understanding of PCR. |
| Year(s) Of Engagement Activity | 2023,2024 |
| Description | Lab Techniques: PCR in Action. Video designed to support Higher Biology and Higher Human Biology learners to develop their knowledge and understanding of gel electrophoresis. |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Schools |
| Results and Impact | This video has been designed to support Higher Biology and Higher Human Biology learners to develop their knowledge and understanding of gel electrophoresis. |
| Year(s) Of Engagement Activity | 2023,2024 |
| Description | Meet a Roslin Scientist - Free downloadable resources created to engage and inspire upper primary pupils, secondary pupils and teachers |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Schools |
| Results and Impact | Free downloadable resources created to engage and inspire upper primary pupils, secondary pupils and teachers, based on our collection of "Meet a Roslin Scientist" short videos and scientist profiles that explore what scientists do, who they are and how they got into science. |
| Year(s) Of Engagement Activity | 2023,2024 |
| Description | Science @Home- Marvellous Mixtures. 'Science @Home' investigation (designed for families to use with young learners aged 9-14) used to explore the question "Can I separate my leafy mixture?". |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Schools |
| Results and Impact | This 'Science @Home' investigation (designed for families to use with young learners aged 9-14) is used to explore the question "Can I separate my leafy mixture?". The investigation builds confidence in using the scientific method and reveals RI research using chromatography to analyse metabolites. |
| Year(s) Of Engagement Activity | 2023,2024 |
| Description | article outlining how Epigenetic markers aid understanding of cattle immunity |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | article outlining how Epigenetic markers aid understanding of cattle immunity, it also appears in efeedlink, Dairy Global |
| Year(s) Of Engagement Activity | 2023 |
| Description | article outlining how Cost-efficient analysis helps breed disease-resistant fish |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | the article shows how a Genetic technique makes breeding healthy animals more accessible to small and medium-scale fish farming producers and is A cost-effective method for breeding rainbow trout to be resistant to a common bacterial infection which has been developed by scientists. |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.ed.ac.uk/roslin/news-events/latest-news-2023/cost-efficient-analysis-helps-breed-disease... |
| Description | article outlining how Gene-edited chickens take a significant step in bird flu fight plus associated news coverage |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | report shows how Alterations to key gene associated with infection offer partial protection and suggest path to flu-resistant poultry where Scientists have used gene-editing techniques to identify and change parts of chicken DNA that could limit the spread of the bird flu virus in the animals and Researchers were able to restrict - but not completely block - the virus from infecting chickens by altering a small section of their DNA. The birds showed no signs that the change in their DNA had any impact on their health or wellbeing. This also appeared in |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.ed.ac.uk/roslin/news-events/latest-news-2023/gene-edited-chickens-are-significant-step-i... |
| Description | article outlining how Wild red deer gene analysis informs management plans |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | article reporting that Genetic studies highlight the species' genetic diversity and population structure, with implications for conservation and wildlife management. Insights into the genetic diversity of wild red deer populations in France may inform plans to further develop how they are managed. |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.ed.ac.uk/roslin/news-events/latest-news-2023/wild-red-deer-gene-analysis-informs-managem... |
| Description | article outlining how a Key gene blocks spillover of avian flu to humans |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | the article explains how Newly identified gene shown to prevent most strains of bird flu from causing infection in humans. Understanding the genetic make-up of currently circulating avian flu strains may offer one of the best lines of defence against widespread human transmission according to new research that has found a key human gene responsible for blocking most avian flu viruses from spilling over into people. |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.ed.ac.uk/roslin/news-events/latest-news-2023/key-gene-blocks-spillover-of-avian-flu-to-h... |
| Description | article outlining how a Project aims to curb losses from major cattle pest |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | article outlining how Roslin experts join collaboration to mitigate impact of Asian blue tick on herds around the world noting that Scientists are working with commercial partners to tackle the world's most devastating cattle tick, which causes billions of dollars of losses to farmers worldwide and reporting that Researchers at the Roslin Institute are working with partners Oxitec to develop a method of managing the invasive Asian blue tick, Rhipicephalus microplus, which spreads diseases through biting cattle. Article also appears in Overblog, The Cattle Site, The Beef Site, The Dairy Site |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.ed.ac.uk/roslin/news-events/latest-news-2023/project-aims-to-curb-losses-from-major-catt... |
| Description | article outlining how a particular Pig gene is critical for African Swine Fever infection |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | article reporting how a Lab study pinpoints immunity-linked gene in pigs that is required for African Swine Fever virus to replicate. Scientists have pinpointed a gene in the DNA of pigs that is needed by a deadly virus to cause infection. Their discovery could inform the development of pigs resistant to African Swine Fever (ASF), a swift acting, severe condition that causes widespread illness and death, incurring high losses for the pork industry. Also appears in "Rurales El Pais, The Pig Site, Head Topics Switzerland, aiz.info, Pig World, Time News, Proplanta, Agriwatch, Interempresas Scottish Farmer, VetCommunity, MRCVS Online, Texas Agriculture Daily, Fleischwirtschaft, Ontario Farmer, Agrarheute, Zooinform.ru" |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.ed.ac.uk/roslin/news-events/latest-news-2023/pig-gene-is-critical-for-african-swine-feve... |
| Description | article outlining that the University and ILRI renew livestock research partnership |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | article around the Renewed Memorandum of Understanding creating research alliance to transform food systems and enhance sustainable livestock production. Article also appeared in Why Africa, Ghana News Online, Research Professional News |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.ed.ac.uk/roslin/news-events/latest-news-2023/university-and-ilri-renew-livestock-researc... |
| Description | article reporting on a Summer school focussing on infectious disease research |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | article outlining how an international initiative helps early career scientists develop their skills in studying infectious diseases where An international summer school in Sweden has enabled early career scientists to develop valuable skills in infectious disease modelling and control. |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.ed.ac.uk/roslin/news-events/latest-news-2023/summer-school-focuses-on-infectious-disease... |
| Description | web article outlining how a Multi-species study aids understanding of bird flu |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | news reports about a study how the Response to infection in birds from chickens to crows points to biological factors linked to disease resistance. Investigations of how various bird species respond to avian flu have enabled insights into the disease. The findings, from a study by Roslin scientists, point towards immune processes and key genes that may play a part in how various species respond to infection. Outcomes from the study may help inform development of commercial poultry that are resistant to the disease. Article also appears in vnonline, mrcvsonline, efeedlink |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.ed.ac.uk/roslin/news-events/latest-news-2023/multi-species-study-aids-understanding-of-b... |