Enhanced Biofuel Production via Integrated Microbubble Technology

Lead Research Organisation: University of Sheffield
Department Name: Molecular Biology and Biotechnology

Abstract

As described in proposal submitted to Innovate UK.

Planned Impact

As described in proposal submitted to Innovate UK.

Publications

10 25 50

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Al-Yaqoobi A (2016) Microbubble Distillation for Ethanol-Water Separation in International Journal of Chemical Engineering

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Calverley J (2021) Continuous removal of ethanol from dilute ethanol-water mixtures using hot microbubbles. in Chemical engineering journal (Lausanne, Switzerland : 1996)

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Calverley J (2020) Hot Microbubble Air Stripping of Dilute Ethanol-Water Mixtures in Industrial & Engineering Chemistry Research

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Chaffin S (2018) Carreau fluid in a wall driven corner flow in Journal of Non-Newtonian Fluid Mechanics

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Chaffin S (2018) Viscoelastic Hele-Shaw flow in a cross-slot geometry in European Journal of Mechanics - B/Fluids

 
Description We have characterized the responses of yeast cells during propagation and fermentation to produce ethanol under conventional and microbubble sparging at laboratory scale. We have completed experiments both wet and computational to better understand the the interactions of microbubbles in biological fermentations to aid the design of a pilot scale demonstration facility, which has now been constructed. Several papers have been been published describing the work undertaken in this project.
Exploitation Route The consortium has an exploitation plan that is discussed with the Monitoring Officer at regular meetings.
Sectors Agriculture

Food and Drink

Chemicals

Energy

Manufacturing

including Industrial Biotechology

 
Description The research undertaken in this project is being discussed with a range of possible users of the technology.
First Year Of Impact 2017
Sector Agriculture, Food and Drink,Chemicals,Energy
 
Description Detoxification and Multi-Resource Recovery from Landfill Leachate
Amount £95,078 (GBP)
Funding ID NE/P016820/1 
Organisation Natural Environment Research Council 
Department NERC Catalyst Grant
Sector Public
Country United Kingdom
Start 03/2017 
End 06/2018
 
Description Energy Catalyst Round 4
Amount £299,848 (GBP)
Funding ID 81773-494638 TS/P007848/1 
Organisation Innovate UK 
Sector Public
Country United Kingdom
Start 03/2017 
End 02/2018
 
Description c1net Proof of Concept Microbubble enhanced gas exchange in a methanotroph gas fermenter
Amount £50,000 (GBP)
Funding ID POC-19-zimmerman-C1net 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 02/2017 
End 05/2018
 
Description Collaboration with 3FBio on Fermentation and Distillation Processes 
Organisation 3f bio
Country United Kingdom 
Sector Private 
PI Contribution Liaison on microbubble mediated aerobic fermentation for bioethanol and protein production with 3FBio's proprietary microorganism and system.
Collaborator Contribution Liaison on microbubble mediated aerobic fermentation for bioethanol and protein production with 3FBio's proprietary microorganism and system.
Impact Still ongoing.
Start Year 2018
 
Description Collaboration with Ensus on Fermentation and Distillation Processes 
Organisation Ensus (Crop Energies)
Country United Kingdom 
Sector Private 
PI Contribution Liaised on recipes for wheat mash production, enzyme addition, and scaling of unit operations to model the Ensus bioethanol process.
Collaborator Contribution Liaised on recipes for wheat mash production, enzyme addition, and scaling of unit operations to model the Ensus bioethanol process.
Impact Ongoing multidisciplinary activity involving microbubble mediated fermentation and distillation processes.
Start Year 2016
 
Description Collaboration with Heineken on Fermentation and Distillation Processes 
Organisation Heineken
Country Netherlands 
Sector Private 
PI Contribution Liasion on microbubble mediated fermentation and distillation processes.
Collaborator Contribution Liasion on microbubble mediated fermentation and distillation processes.
Impact Still ongoing.
Start Year 2018
 
Title FLUIDIC OSCILATORS 
Description A new fluidic oscillator is described comprising at least one inlet port (57) in communication with at least two outlets (61) via a nozzle region A and two outlet conduits (58, 62), the two outlet conduits being separated from each other by a splitter region and each outlet conduit comprising a resonance chamber (60) in fluid communication with the conduit. The resonance chambers are key in controlling the oscillation of the device and the fluidic oscillator is operated through a new acoustic switching mode. 
IP Reference WO2020208250 
Protection Patent application published
Year Protection Granted 2020
Licensed Commercial In Confidence
Impact This new oscillator has been demonstrated to achieve very rapid removal of ammonia from wastewaters and digester centrates, with tuneable liquid volumes, via microbubble distillation. A waste management company has supported pilot scale trials for landfill leachate remediation with this oscillator making the liquid treatment volumes readily engineered via conventional size plumbing.
 
Description Feature Article in the Times of London based on my interview, by Tom Whipple, Science writer 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Feature Article in The Times of London 13 April 2021 by Tom Whipple, science writer, explaining how our work on microbubble mediated heat transfer explained the previously unexplained original Mpemba effect experiments.

The Mpemba effect has baffled scientists and the general public since it was popularized by Mpemba and Osborne in 1969. The Royal Society of Chemistry conducted an international competition in 2012 for the best solution to this mystery, known to have puzzled Aristotle and commented on by da Vinci. My study of microbubble mediated heat transfer gave a constructive model that correlated the original experiments, which have otherwise never been explained. More can be found about the first paper, sequels and a keynote address at the 15th International Conference on Heat Transfer, Fluid Mechanics, and Thermodynamics (2021) where the role of microbubbles is explained.
Year(s) Of Engagement Activity 2021
URL https://www.sheffield.ac.uk/cbe/news/cracked-cold-case-why-boiling-water-freezes-faster
 
Description Outreach activity 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Pint of Science on 16 May 2018
Title: A paradigm shift: ethanol from woody plants
Talk description: We need a paradigm shift in our approach towards the pretreatment of plant biomass to produce products of interest, at high titre, rate and yield. By taking a road less travelled by, perhaps we might be able to become a bio-based society sooner.
Year(s) Of Engagement Activity 2018
 
Description Outreach activity 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Pride in STEM Out Thinkers on 15 November 2018
Title: Unlocking the carbon treasure held within plants through industrial biotechnology
Talk description: The unbridled progress since the industrial revolution and our penchant for petrochemicals has also increased the levels of carbon-dioxide in the planet. Climate change is happening; we must take measures to minimise its impact. Perhaps ethanol, that yeasts happily produce from sugars, offers the solution. Integration of various technologies to make the cost of bioethanol comparable to petrol was discussed in the context of sustainablity.
Year(s) Of Engagement Activity 2018
 
Description Participation in Industry / Academia / Government Workshop on Modelling of Cleaning and Decontamination (ModCaD) leading to a roadmap report 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Please see www.modcad.org

The intended purpose was to quantify the need across practically all sectors of the economy for quantitative modelling of cleaning and decontamination to inform best practise in this highly multidisciplinary sector, underpin innovation (particularly with scientific and engineering based design), and address new challenges such as sustainability, risk, diversity, networking, training, sensors and supporting sciences. From that quantification, the workshop developed a roadmap to tackle strateic investment in communication, community, training and features of the sceince base.
From the point of view of nbic and my feasibility study, my contribution to the roadmap was to highlight the innovations explored with biofilm removal, the need for further development work under conditions appropriate for endusers, and engineering science based modelling for design and understanding of fundamental mechanisms. A similar effort was extended to plasma activated microbubbles to underscore its potential and needs for development.
Year(s) Of Engagement Activity 2021
URL http://www.modcad.org
 
Description Yeast propagation using microbubbles for cost effective bioethanol production 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact 7th Conference on Physiology of Yeasts and Filamentous Fungi
Year(s) Of Engagement Activity 2019