Pericyte-mediated vasoconstriction and hypoperfusion in Alzheimer's disease (AD)"

Lead Research Organisation: University of Bristol
Department Name: Bristol Medical School

Abstract

To clarify the mechanisms of pericyte-mediated cerebral hypoperfusion in AD, pericyte content and activation will be assessed immunohistochemically and biochemically in human brain tissue, and by multiphoton imaging and electrophysiology in cultured human cells and transgenic mouse models under conditions stimulating AD and chronic hypoperfusion."

Publications

10 25 50

Studentship Projects

Project Reference Relationship Related To Start End Student Name
MR/N013794/1 30/09/2016 29/09/2025
2131961 Studentship MR/N013794/1 30/09/2018 30/03/2022 Elliott Hibbs