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Supplementary funding to support the extension of the EDCTP-funded ETEC Vaccine Efficacy study

Lead Research Organisation: European Developing Countries
Department Name: UNLISTED

Abstract

"Supplementary funding to support the extension of the EDCTP-funded trial ""Field studies of an oral whole cell ETEC vaccine candidate in African toddlers and children: Assess efficacy and set parameters for pivotal Phase 3 trials (ETEC Vaccine Efficacy)"" held by Mr Björn Sjöstrand (Scandinavian Biopharma Holding AB, Sweden). Study delayed due to the negative impacts of the Covid-19 pandemic.

ETVAX® is a killed whole-cell oral vaccine against ETEC. ETVAX® produces immunity by preventing ETEC bacteria from adhering to cells of the small intestine and interfering with the effects of ETEC toxins on these cells. Scientists recognize ETVAX as the most clinically advanced ETEC vaccine. The results of the Phase 1 study support the safety, tolerability, and immunogenicity of ETVAX® in adults and children in Zambia. https://scandinavianbiopharma.se/studies/study-oev-124-phase-i-descending-age-study-in-a-lmic/ and https://scandinavianbiopharma.se/studies/oev-128-phase-iib-study-in-children-6-18-months-in-a-lmic/"

Technical Summary

"Supplementary funding to support the extension of the EDCTP-funded trial ""Field studies of an oral whole cell ETEC vaccine candidate in African toddlers and children: Assess efficacy and set parameters for pivotal Phase 3 trials (ETEC Vaccine Efficacy)"" held by Mr Björn Sjöstrand (Scandinavian Biopharma Holding AB, Sweden). Study delayed due to the negative impacts of the Covid-19 pandemic.

ETVAX® is a killed whole-cell oral vaccine against ETEC. ETVAX® produces immunity by preventing ETEC bacteria from adhering to cells of the small intestine and interfering with the effects of ETEC toxins on these cells. Scientists recognize ETVAX as the most clinically advanced ETEC vaccine. The results of the Phase 1 study support the safety, tolerability, and immunogenicity of ETVAX® in adults and children in Zambia. https://scandinavianbiopharma.se/studies/study-oev-124-phase-i-descending-age-study-in-a-lmic/ and https://scandinavianbiopharma.se/studies/oev-128-phase-iib-study-in-children-6-18-months-in-a-lmic/
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