Immunology: Understanding the molecular and cellular basis of Immunity: The Persistence of Humoral Memory
Lead Research Organisation:
Babraham Institute
Department Name: UNLISTED
Abstract
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Technical Summary
Mechanisms determining how B cells become long lived antibody secreting cells are addressed
Planned Impact
unavailable
Organisations
| Description | Our work on responses to antigen variation has been reported on plenary session talks at major international conferences and seminar presentations in Europe and Japan. It has been widely cited and led to current collaborations with Univ. Basel and the Pirbright Institute. Our interest in vaccination led to a project on generating vaccines inducing self-reactive responses to cancer. This led to a patent and downstream funding applications, partly with industry (current funding application for collaboration with Alchemab). Expertise on antibody responses led to membership in the Scientific Advisory Board of Alloy Therapeutics, advising on generation of transgenic animals that can be used as tools for the generation of new monoclonal antibody drugs |
| Exploitation Route | Immunotherapy |
| Sectors | Manufacturing including Industrial Biotechology |