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Maximising patient benefit: Leeds’ Interdisciplinary approach to translation

Lead Research Organisation: University of Leeds
Department Name: UNLISTED

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Technical Summary

The Confidence in Concept scheme is a key part of MRC’s translational research strategy and provides annual awards to institutions, to be used flexibly to support the earliest stages of multiple translational research projects. The award can be used by the institution to support a number of preliminary-stage translational projects. The projects supported should aim to provide sufficient preliminary data to establish the viability of an approach –– before seeking more substantive funding.  It is intended to accelerate the transition from discovery research to translational development projects by supporting preliminary work or feasibility studies to establish the viability of an approach.

Publications

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Yin J (2021) Hierarchically Assembled Type I Collagen Fibres as Biomimetic Building Blocks of Biomedical Membranes. in Membranes

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Jenkinson C (2016) High throughput LC-MS/MS method for the simultaneous analysis of multiple vitamin D analytes in serum. in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

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Weigel M (2017) Immediate versus modified release hydrocortisone in mitotane-treated patients with adrenocortical cancer in Clinical Endocrinology

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Arafat M (2019) In-situ crosslinked wet spun collagen triple helices with nanoscale-regulated ciprofloxacin release capability in Materials Letters

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Owston HE (2020) Induced Periosteum-Mimicking Membrane with Cell Barrier and Multipotential Stromal Cell (MSC) Homing Functionalities. in International journal of molecular sciences

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Schiffer L (2023) Inhibition of the glucocorticoid-activating enzyme 11ß-hydroxysteroid dehydrogenase type 1 drives concurrent 11-oxygenated androgen excess

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Schiffer L (2024) Inhibition of the glucocorticoid-activating enzyme 11ß-hydroxysteroid dehydrogenase type 1 drives concurrent 11-oxygenated androgen excess in The FASEB Journal

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Larner D (2016) Male 11ß-HSD1 Knockout Mice Fed Trans-Fats and Fructose Are Not Protected From Metabolic Syndrome or Nonalcoholic Fatty Liver Disease in Endocrinology

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Clayton RN (2016) Mortality in patients with Cushing's disease more than 10 years after remission: a multicentre, multinational, retrospective cohort study. in The lancet. Diabetes & endocrinology

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Mahmoud K (2017) Musculoskeletal manifestations of systemic lupus erythmatosus. in Current opinion in rheumatology