Establishment of a National Network on Musculoskeletal Ageing
Lead Research Organisation:
University of Southampton
Department Name: UNLISTED
Abstract
Our overall aim is to establish a new national network which will underpin a step change in musculoskeletal ageing research capacity and strategy, by identifying: key tractable research priorities; developing an integrated multi-disciplinary grouping to address the identified research gaps; providing a platform to disseminate best practice; supporting Early Career Researchers (ECRs) to build research capacity and ensure longevity to current UKRI investments; and coordinating an ongoing programme of innovative studies to identify, develop and translate findings from our discovery science to clinical impact. Crucially the network will contribute to delivering the government āGrand Challengeā target of 5 more years of independent living by 2035, by identifying approaches to maintain mobility in old age. The network will bring together the scientific excellence of the three principal applicants. Focusing on the leading chronic non-communicable disorders of bone, muscle and joint (osteoporosis, sarcopenia, rheumatoid arthritis and osteoarthritis), the integration of these groups will galvanize a truly bench to bedside approach to provide a strong evidence base for health policy, underpinning a step change in UK musculoskeletal ageing research capability/capacity, and promoting increased healthspan.
Technical Summary
Our overall aim is to establish a new national network which will underpin a step change in musculoskeletal ageing research capacity and strategy, by identifying: key tractable research priorities; developing an integrated multi-disciplinary grouping to address the identified research gaps; providing a platform to disseminate best practice; supporting Early Career Researchers (ECRs) to build research capacity and ensure longevity to current UKRI investments; and coordinating an ongoing programme of innovative studies to identify, develop and translate findings from our discovery science to clinical impact. Crucially the network will contribute to delivering the government āGrand Challengeā target of 5 more years of independent living by 2035, by identifying approaches to maintain mobility in old age. The network will bring together the scientific excellence of the three principal applicants. Focusing on the leading chronic non-communicable disorders of bone, muscle and joint (osteoporosis, sarcopenia, rheumatoid arthritis and osteoarthritis), the integration of these groups will galvanize a truly bench to bedside approach to provide a strong evidence base for health policy, underpinning a step change in UK musculoskeletal ageing research capability/capacity, and promoting increased healthspan.
Organisations
- University of Southampton (Lead Research Organisation)
- University of Leeds (Collaboration)
- UNIVERSITY OF NOTTINGHAM (Collaboration)
- UNIVERSITY OF BIRMINGHAM (Collaboration)
- University of Bristol (Collaboration)
- NEWCASTLE UNIVERSITY (Collaboration)
- Royal Osteoporosis Society (Collaboration)
- UNIVERSITY OF LIVERPOOL (Collaboration)
- University of Manchester (Collaboration)
- Edith Cowan University (Collaboration)
- UNIVERSITY OF SHEFFIELD (Collaboration)
People |
ORCID iD |
| Cyrus Cooper (Principal Investigator) |
Publications
Lorentzon M
(2022)
Menopausal hormone therapy reduces the risk of fracture regardless of falls risk or baseline FRAX probability-results from the Women's Health Initiative hormone therapy trials.
in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Abdulla N
(2022)
Epidemiology of hip fracture in Qatar and development of a country specific FRAX model.
in Archives of osteoporosis
Burton MA
(2023)
Adiposity is associated with widespread transcriptional changes and downregulation of longevity pathways in aged skeletal muscle.
in Journal of cachexia, sarcopenia and muscle
Kanis JA
(2023)
The need to distinguish intervention thresholds and diagnostic thresholds in the management of osteoporosis.
in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Sing CW
(2023)
Global Epidemiology of Hip Fractures: Secular Trends in Incidence Rate, Post-Fracture Treatment, and All-Cause Mortality.
in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Dennison EM
(2023)
Do lifestyle, anthropometric and demographic factors associated with muscle strength differ in a UK and Japanese cohort? An exploratory analysis.
in Aging clinical and experimental research
Burton MA
(2023)
DNA methylation of insulin signaling pathways is associated with HOMA2-IR in primary myoblasts from older adults.
in Skeletal muscle
Sharif N
(2023)
Machine learning for abdominal aortic calcification assessment from bone density machine-derived lateral spine images
in eBioMedicine
Honvo G
(2023)
Measures of attributes of locomotor capacity in older people: a systematic literature review following the COSMIN methodology.
in Age and ageing
| Title | International Osteoporosis Foundation Advanced Osteoporosis Course Welcome Video |
| Description | Welcome video for Advanced Osteoporosis Course |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2025 |
| Impact | Ongoing |
| Title | Introduction for New Zealand Parliament Osteoporosis Celebration |
| Description | Video recorded as Pres of International Osteoporosis Foundation to introduce session. |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2025 |
| Impact | Ongoing |
| Title | Introductory video for Ukraine Osteoporosis Society conference |
| Description | Prof Harvey gave welcome introductory video for conference on behalf of International Osteoporosis Foundation |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2024 |
| Impact | Ongoing |
| Description | Co-authorship of European guidance on osteoporosis in men (ESCEO) |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | Co-authorship of European position on Real World Evidence in osteoporosis |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | Co-authorship of Royal Osteoporosis Society APPG enquiry into Primary fracture prevention(NCH) 2022 |
| Geographic Reach | National |
| Policy Influence Type | Contribution to a national consultation/review |
| Description | Co-authorship of Royal Osteoporosis Society APPG enquiry into Primary fracture prevention(NCH) 2022 |
| Geographic Reach | National |
| Policy Influence Type | Contribution to a national consultation/review |
| Description | ESCEO guidance on neurological disease and bone health |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | ESCEO position paper on osteoporosis and osteoarthritis in the oldest old |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | European guidance on very high fracture risk (NCH, CC) |
| Geographic Reach | Europe |
| Policy Influence Type | Membership of a guideline committee |
| Description | International Osteoporosis Foundation Working Group on equitable access to optimal bone health management |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | International guidance on anabolic therapy for osteoporosis |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | Led European Recommendations on management of male osteoporosis |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Contribution to new or improved professional practice |
| Description | National Osteoporosis Guideline Group Advisory Committee (NCH, CC) |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | UK Biobank Frailty and Ageing Working Group (Chair) |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | British Society for Paediatric Endocrinology and Diabetes Research & Innovation Award 2024 |
| Amount | Ā£15,000 (GBP) |
| Organisation | Royal College of Paediatrics and Child Health (RCPCH) |
| Department | British Society for Paediatric Endocrinology and Diabetes (BSPED) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2025 |
| End | 01/2027 |
| Description | Capital equipment grant (DXA scanner) |
| Amount | Ā£142,000 (GBP) |
| Organisation | National Institute for Health and Care Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2024 |
| End | 03/2025 |
| Description | Does pregnancy vitamin D supplementation alter trajectories of body composition and bone mineralisation from early childhood to adolescence? Follow-up of a randomised placebo-controlled trial. |
| Amount | Ā£187,294 (GBP) |
| Funding ID | GN2969 |
| Organisation | Action Medical Research |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 05/2023 |
| End | 06/2026 |
| Description | Does pregnancy vitamin D supplementation alter trajectories of body composition and bone mineralisation from early childhood to adolescence? Follow-up of a randomised placebo-controlled trial. |
| Amount | Ā£187,294 (GBP) |
| Funding ID | GN2969 |
| Organisation | Action Medical Research |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2023 |
| End | 03/2026 |
| Description | NIHR Clinical Lectureship |
| Amount | Ā£250,000 (GBP) |
| Funding ID | CL-2020-26-002 |
| Organisation | National Institute for Health and Care Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2021 |
| End | 11/2026 |
| Description | NIHR Southampton BRC PhD studentship |
| Amount | Ā£70,000 (GBP) |
| Organisation | National Institute for Health and Care Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 08/2024 |
| End | 09/2027 |
| Description | Nutritional determinants of skeletal development and bone loss: an investigation using a novel computer vision assessment of bone microarchitecture |
| Amount | Ā£36,000 (GBP) |
| Organisation | University of Southampton |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 08/2022 |
| End | 09/2025 |
| Description | PhD studentship (Computer vision in bone develoment) |
| Amount | Ā£35,000 (GBP) |
| Organisation | University of Southampton |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 09/2022 |
| End | 10/2025 |
| Description | Preventing broken bones in older people: from research to policy to practice |
| Amount | Ā£29,566 (GBP) |
| Funding ID | MRF-145-0011-DG-HARV-C0913 |
| Organisation | Medical Research Council (MRC) |
| Department | Medical Research Foundation |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2022 |
| End | 09/2022 |
| Title | Dataset for paper :Maternal and fetal genetic variation in vitamin D metabolism and umbilical cord blood 25-hydroxyvitamin D - Supplemental Tables and Figures |
| Description | Supplemental tables and figures to accompany the paper "Maternal and fetal genetic variation in vitamin D metabolism and umbilical cord blood 25-hydroxyvitamin D" by RJ Moon, LDF Cooke, S D'Angelo, EM Curtis, P Titcombe, JH Davies, KM Godfrey, JK Cleal, RM Lewis, C Cooper & NC Harvey |
| Type Of Material | Database/Collection of data |
| Year Produced | 2022 |
| Provided To Others? | Yes |
| Impact | Supplemental tables and figures to accompany the paper "Maternal and fetal genetic variation in vitamin D metabolism and umbilical cord blood 25-hydroxyvitamin D" by RJ Moon, LDF Cooke, S D'Angelo, EM Curtis, P Titcombe, JH Davies, KM Godfrey, JK Cleal, RM Lewis, C Cooper & NC Harvey |
| URL | https://eprints.soton.ac.uk/455706/ |
| Description | AUGMENT UK Biobank collaboration |
| Organisation | University of Bristol |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | AUGMENT UK Biobank collaboration |
| Collaborator Contribution | AUGMENT UK Biobank collaboration |
| Impact | AUGMENT UK Biobank collaboration |
| Start Year | 2017 |
| Description | AUGMENT UK Biobank collaboration |
| Organisation | University of Manchester |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | AUGMENT UK Biobank collaboration |
| Collaborator Contribution | AUGMENT UK Biobank collaboration |
| Impact | AUGMENT UK Biobank collaboration |
| Start Year | 2017 |
| Description | Abdominal Aortic Calcification Collaboration |
| Organisation | Edith Cowan University |
| Country | Australia |
| Sector | Academic/University |
| PI Contribution | Collaboration using AI techniques to detect abdominal aortic calcification. Collaboration between Edith Cowan University and University of Western Australia; McMaster University; University of Manitoba; University of Southampton. Southampton providing UK biobank expertise. |
| Collaborator Contribution | Collaboration using AI techniques to detect abdominal aortic calcification. Collaboration between Edith Cowan University and University of Western Australia; McMaster University; University of Manitoba; University of Southampton. Southampton providing UK biobank expertise. |
| Impact | Ongoing |
| Start Year | 2021 |
| Description | Arthroplasty prediction Collaboration |
| Organisation | University of Bristol |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Leadership of international consortium to develop risk model for arthroplasty |
| Collaborator Contribution | Leadership |
| Impact | Initial stages |
| Start Year | 2024 |
| Description | Arthroplasty prediction Collaboration |
| Organisation | University of Leeds |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Leadership of international consortium to develop risk model for arthroplasty |
| Collaborator Contribution | Leadership |
| Impact | Initial stages |
| Start Year | 2024 |
| Description | Arthroplasty prediction Collaboration |
| Organisation | University of Sheffield |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Leadership of international consortium to develop risk model for arthroplasty |
| Collaborator Contribution | Leadership |
| Impact | Initial stages |
| Start Year | 2024 |
| Description | EU PROBE Osteoarthritis collaboration |
| Organisation | University of Leeds |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Multi-partner international collaboration focused on EU call for osteoarthritis. |
| Collaborator Contribution | Grant co-applicant focused on risk assessment for osteoarthritis |
| Impact | In initial stages |
| Start Year | 2024 |
| Description | MRC National Musculoskeletal Ageing Network |
| Organisation | Newcastle University |
| Country | United Kingdom |
| PI Contribution | MRC National Musculoskeletal Ageing Network, Comprising MRC Lifecourse Epidemiology Centre, MRC-Versus Arthritis Centre for Integrated research in Musculoskeletal Ageing (CIMA), MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research (CMAR), MRC Epidemiology Unit, MRC Integrative Epidemiology Unit, and MRC Unit for Lifelong Health and Ageing. Together these span the Universities of Southampton, Sheffield, Liverpool, Newcastle, Nottingham, Birmingham, Oxford, Bristol, Cambridge and UCL, with further links to associated NIHR Biomedical Research Centres. |
| Collaborator Contribution | Development of novel strategy to address frailty transition in older age |
| Impact | Publish strategy paper, workshops, seminars, grant applications. |
| Start Year | 2022 |
| Description | MRC National Musculoskeletal Ageing Network |
| Organisation | University of Birmingham |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | MRC National Musculoskeletal Ageing Network, Comprising MRC Lifecourse Epidemiology Centre, MRC-Versus Arthritis Centre for Integrated research in Musculoskeletal Ageing (CIMA), MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research (CMAR), MRC Epidemiology Unit, MRC Integrative Epidemiology Unit, and MRC Unit for Lifelong Health and Ageing. Together these span the Universities of Southampton, Sheffield, Liverpool, Newcastle, Nottingham, Birmingham, Oxford, Bristol, Cambridge and UCL, with further links to associated NIHR Biomedical Research Centres. |
| Collaborator Contribution | Development of novel strategy to address frailty transition in older age |
| Impact | Publish strategy paper, workshops, seminars, grant applications. |
| Start Year | 2022 |
| Description | MRC National Musculoskeletal Ageing Network |
| Organisation | University of Liverpool |
| Department | School of Medicine Liverpool |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | MRC National Musculoskeletal Ageing Network, Comprising MRC Lifecourse Epidemiology Centre, MRC-Versus Arthritis Centre for Integrated research in Musculoskeletal Ageing (CIMA), MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research (CMAR), MRC Epidemiology Unit, MRC Integrative Epidemiology Unit, and MRC Unit for Lifelong Health and Ageing. Together these span the Universities of Southampton, Sheffield, Liverpool, Newcastle, Nottingham, Birmingham, Oxford, Bristol, Cambridge and UCL, with further links to associated NIHR Biomedical Research Centres. |
| Collaborator Contribution | Development of novel strategy to address frailty transition in older age |
| Impact | Publish strategy paper, workshops, seminars, grant applications. |
| Start Year | 2022 |
| Description | MRC National Musculoskeletal Ageing Network |
| Organisation | University of Nottingham |
| Department | School of Biology Nottingham |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | MRC National Musculoskeletal Ageing Network, Comprising MRC Lifecourse Epidemiology Centre, MRC-Versus Arthritis Centre for Integrated research in Musculoskeletal Ageing (CIMA), MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research (CMAR), MRC Epidemiology Unit, MRC Integrative Epidemiology Unit, and MRC Unit for Lifelong Health and Ageing. Together these span the Universities of Southampton, Sheffield, Liverpool, Newcastle, Nottingham, Birmingham, Oxford, Bristol, Cambridge and UCL, with further links to associated NIHR Biomedical Research Centres. |
| Collaborator Contribution | Development of novel strategy to address frailty transition in older age |
| Impact | Publish strategy paper, workshops, seminars, grant applications. |
| Start Year | 2022 |
| Description | MRC National Musculoskeletal Ageing Network |
| Organisation | University of Sheffield |
| Department | Sheffield Biorepository |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | MRC National Musculoskeletal Ageing Network, Comprising MRC Lifecourse Epidemiology Centre, MRC-Versus Arthritis Centre for Integrated research in Musculoskeletal Ageing (CIMA), MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research (CMAR), MRC Epidemiology Unit, MRC Integrative Epidemiology Unit, and MRC Unit for Lifelong Health and Ageing. Together these span the Universities of Southampton, Sheffield, Liverpool, Newcastle, Nottingham, Birmingham, Oxford, Bristol, Cambridge and UCL, with further links to associated NIHR Biomedical Research Centres. |
| Collaborator Contribution | Development of novel strategy to address frailty transition in older age |
| Impact | Publish strategy paper, workshops, seminars, grant applications. |
| Start Year | 2022 |
| Description | ROS MRF APPG collaboration |
| Organisation | Royal Osteoporosis Society |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Collaboration on developing policy for primary fracture prevention with Royal Osteoporosis Society, University of Southampton and University of Sheffield |
| Collaborator Contribution | Collaboration on developing policy for primary fracture prevention with Royal Osteoporosis Society, University of Southampton and University of Sheffield |
| Impact | As per publications and APPG report |
| Start Year | 2022 |
| Description | ROS MRF APPG collaboration |
| Organisation | University of Sheffield |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration on developing policy for primary fracture prevention with Royal Osteoporosis Society, University of Southampton and University of Sheffield |
| Collaborator Contribution | Collaboration on developing policy for primary fracture prevention with Royal Osteoporosis Society, University of Southampton and University of Sheffield |
| Impact | As per publications and APPG report |
| Start Year | 2022 |
| Description | A talk at CIMA/CMAR Joint Meeting, Birmingham |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | CIMA/CMAR Network Meeting/Presentation |
| Year(s) Of Engagement Activity | 2023 |
| Description | ACCIA 2022 Committee Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | This meeting was held via Zoom on 9th June 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Abstract Writing Masterclass |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Nick Harvey presented the MRC National Musculoskeletal Ageing Network abstract writing seminar, which took place on December 13th 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Article for University of Southampton Medically Speaking Blog |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Article witten for Medically Speaking Blog, University of Southampton |
| Year(s) Of Engagement Activity | 2023 |
| Description | Article written by Nick Harvey in UoS Enews |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Nick Harvey wrote an article for the University of Southampton Enews in which he wrote about the welcome return to face-face- meetings; the opportunity for in-person participation in the American Society for Bone and Mineral Research Annual Scientific Conference in Austin, Texas and to be able to catch up with colleagues and friends from all over the world. He also mentioned that the new term brings progression of a major initiative in UK musculoskeletal science with the consolidation of the strategic framework for our UKRI MRC National Musculoskeletal Ageing Network. The network will be led by the University of Southampton. He also added that it was great to see the exciting news of the UK Biobank Repeat Imaging Study recently made public. |
| Year(s) Of Engagement Activity | 2022 |
| Description | BRS ECTS Liverpool |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Speech at BRS ECTS Liverpool |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://boneresearchsociety.org/meetings/198/ |
| Description | BSRA MRC National Musculoskeletal Ageing Network joint symposium 2023 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | BSRA MRC National Musculoskeletal Ageing Network joint symposium 2023 |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://bsra.org.uk/events/bsra-asm-2023/ |
| Description | Blog and E News |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Schools |
| Results and Impact | Professor Nicholas Harvey has been appointed as Director of the MRC LEC. He takes over from Cyrus Cooper on 1st April 2023 |
| Year(s) Of Engagement Activity | 2023 |
| Description | Centre of Excellence Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on 7th June 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | DOHAD Conference 2022 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus attended the DOHAD International Conference. This was held between 27th-31st August 2022. Over 1,000 people attended. |
| Year(s) Of Engagement Activity | 2022 |
| Description | DOHAD Society webinar |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | DOHAD Society webinar |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://dohadsoc.org/webinars/ |
| Description | ESCEO Working Group |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended the ESCEO Working Group on September 9th 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Editorial Team invite |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Kate Ward and Nick Harvey joined the editorial team of the journals of osteoporosis international and archives of osteoporosis |
| Year(s) Of Engagement Activity | 2023 |
| Description | European Geriatric Medical Society |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | speech/presentation for EUGMS |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://eugms2023.com/ |
| Description | Expert Health Article in The Telegraph |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Kate Ward gave an interview for the Expert Health feature in the Telegraph newspaper. |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.telegraph.co.uk/health-fitness/conditions/bones-joints/im-a-bone-health-expert-and-this-... |
| Description | External Meeting at The Usher Institute, Edinburgh |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus attended the NINE Edinburgh BioQuater meeting on 24th May 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Gestational vitamin D supplementation: observation mechanism and intervention in the MAVIDOS trial. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Nick Harvey gave a talk at the BSR Science Forum on 18th February 2022. Up to 50 people attended. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Hosting MRC National Musculoskeletal Ageing Network Webinar series |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | MRC LEC hosts and leads the MRC National Musculoskeletal Ageing Network Webinar series |
| Year(s) Of Engagement Activity | 2023,2024 |
| Description | IOF symposium at DVO Congress, Salzburg |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | IOF at DVO conference |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.emedevents.com/c/medical-conferences-2023/annual-congress-dvo-osteology-2023 |
| Description | Launch of the MRC Lifecourse Epidemiology Centre & MRC National Musculoskeletal Group |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | The launch of the MRC Lifecourse Epidemiology Centre and the MRC National Musculoskeletal Ageing Network was an online event. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://us06web.zoom.us/rec/play |
| Description | Lay presentation |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Nick Harvey delivered a lay presentation on Osteoporosis to the Patient Partner Group at the St Francis Surgery in Hedge End, Southampton. Around 100 people attended. |
| Year(s) Of Engagement Activity | 2023 |
| Description | Lectures for IOF Advance Osteoporosis Course |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | MRC LEC team members recorded lectures for the new online International Osteoporosis Foundation Advanced Osteoporosis Course |
| Year(s) Of Engagement Activity | 2024 |
| Description | MRC LEC Research review panel |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Meetings of the MRCLEC Patient led Research Review Panel |
| Year(s) Of Engagement Activity | 2024 |
| Description | MRC National Musculoskeletal Ageing Network ECR/MCR developmental sessions |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | MRC National Musculoskeletal Ageing Network ECR/MCR developmental sessions |
| Year(s) Of Engagement Activity | 2022 |
| Description | MRC National Musculoskeletal Ageing Network Seminars |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | MRC National Musculoskeletal Ageing Network Seminars |
| Year(s) Of Engagement Activity | 2022 |
| Description | MyAge London |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | MyAge published a roadmap to help shape the future of muscle resilience research |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.ukanet.org.uk/myage/news-events/ |
| Description | Osteoarthritis focus groups |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Undertook focus groups for an osteoarthritis project in Southampton and Leeds and Sheffield. |
| Year(s) Of Engagement Activity | 2024 |
| Description | Participant in Committee Meeting HDR UK QQR Research Driver Programmes Sub-committee meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper was part of this meeting which took place on 25 May 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Presentation at Prizegiving event |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper presented a prize at the Rank Prize 50th Anniversary event. This took place on 4th July 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Presentation given at ESCEO Meeting |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus gave a presentation entitled "Optamising the prescription of oral Bisphosphonates" |
| Year(s) Of Engagement Activity | 2022 |
| Description | Presentation to Royal Osteoporosis Society Southampton Group |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Presentation to Osteoporosis Society Southampton Group |
| Year(s) Of Engagement Activity | 2024 |
| Description | Press Release and publication of paper |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Press release for the paper entitled "Is the skull responsive to bone mineralisation stimuli in children? published in the journal Bone. There was some media attention following the publication of this paper. The press release was entitled "Skulls stay strong despite worse diets" |
| Year(s) Of Engagement Activity | 2022 |
| Description | Press Release of published paper |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | There were a number of online citings following a press release entitled "Three coffees a day could help keep the doctor away." This was to do with an article published in European Journal of Preventive Cardiology entitled: Light to moderated coffee consumption is associated with lower risk of death: UK Biobank Study. Simon J, Fung K, et al. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Press release for published paper |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | A press release came out on 12th August 2022 for the paper entitled "Menopausal hormone therapy reduces the risk of fracture regardless of falls risk or baseline FRAX probability - results from the Women's Health Initiative hormone therapy trials." The paper was published in Osteoporosis International. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Preventing broken bones in older people: from research to policy to practice |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | The University Faculty of Medicine print a Research Roundup Newsletter. These newsletters aim to celebrate success, provide research updates and give information on upcoming opportunities. The second of these newsletters was written by Professor Nick Harvey. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Public engagement session on osteoporosis with primary care patients |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Speech on Osteoporosis to St Thomas's Practice |
| Year(s) Of Engagement Activity | 2019,2023 |
| Description | REF 2021 University Results Presentation |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus attended the REF2021 University Results Presentation meeting on 9th May 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | ROS APPG Report |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Royal Osteoporosis Society All Party Parliamentary Group in Osteoporosis Enquiry into primary fracture prevention, partly supported by MRF grant |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://strwebprdmedia.blob.core.windows.net/media/vxuhotlh/appg-on-osteoporosis-and-bone-health-inq... |
| Description | Royal Osteoporosis Society |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | speech and presentation |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://theros.org.uk/healthcare-professionals/courses-and-cpd/osteoporosis-conference/ |
| Description | Saudi NH first advisory Committee Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus attended this meeting on 18th May 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Southampton Women's Survey Celebration Event |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | As part of the 50th Anniversary of the NIHR BRC, the Southampton Women's Survey were chosen to represent some of the research that has taken place in Southampton. The BRC funded an evening at the City Art Gallery in Southampton for 50 SWS participants and their family or friends. The speakers who talked about the study findings were Prof. Cyrus Copper, Prof Keith Godfrey, Prof Janis Baird and Prof Hazel Inskip who wrote and sang a song at the end of the presentation whilst playing her ukulele. SWS staff in attendance and who organised the logistics for the event were research nurses, Julia Hammond, Nicole Minette, Karen McGill and Tina Horsfall. They received requests about further participation or involvement, the audience reported change in views, opinions or behaviours, requests for further information. Children were also recruited for PPI for the BRC. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Talk at Cafe Scientifique |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Presentation by Prof Nicholas Harvey on osteoporosis to the Chandlers Ford Cafe Scientifique |
| Year(s) Of Engagement Activity | 2024 |
| Description | The American Society for Bone and Mineral Research |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation The American Society for Bone and Mineral Research |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.asbmr.org/annual-meeting |
| Description | UKRI MyAge launch event (Muscle resilience across the life course: from cells to Society. |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus attended this event on 24th May 2022 |
| Year(s) Of Engagement Activity | 2022 |
| Description | University Hospital Southampton Members Webinar |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | University Hospital Southampton Members Webinar (N Harvey presented) |
| Year(s) Of Engagement Activity | 2024 |
| Description | University of Southampton Science and Engineering Day |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Nick Harvey was part of a team from the MRC LEU that took part in this event. The event was well attended with members of the public showing great interest. |
| Year(s) Of Engagement Activity | 2022 |
| Description | WCO-IOF-ESCEO Conference - Virtual |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Nick Harvey, Deputy Director of MRC LEU gave the Plenary Lecture 2 entitled 'Update of the management of patients at imminent fracture risk at the WCO-IOF-ESCEO conference on 24th March 2022, which was held virtually. This was attended by over 1,000 people. |
| Year(s) Of Engagement Activity | 2022 |
| Description | WHO and Osteoporosis meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus attended this meeting on 28th June 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | WORLD CONGRESS ON OSTEOPOROSIS, OSTEOARTHRITIS AND MUSCULOSKELETAL DISEASES |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentaiton of IOF Presidents Award |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.wco-iof-esceo.org/ |
| Description | online interview |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Nick Fuggle gave an interview about the highlights of the WCO IOF ESCEO meeting i.e. risk prediction, machine learning and computer vision. This was published by touch immunology on 12th June 2023 |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.touchimmunology.com/osteoarthritis/conference-hub/wco-iof-esceo-meeting-highlights-2023-... |