Molecular dams: de-repression mechanisms in plant temperature sensing (DEAN_J17DTP)
Lead Research Organisation:
University of East Anglia
Department Name: Graduate Office
Abstract
The project will exploit the power of Arabidopsis genetics to identify and analyse regulators of temperature dependent gene expression. We will focus on cold induction of a gene called VIN3 - that is required for plants to sense and respond to winter. The project will dissect how this gene is kept off transcriptionally in the warm and allowed to be expressed only when temperatures become cold. Understanding from this project is likely to be widely relevant to chromatin regulation and environmental sensing across a wide range of organisms.
Organisations
People |
ORCID iD |
Publications
Zhao Y
(2020)
Publisher Correction: Temperature-dependent growth contributes to long-term cold sensing.
in Nature
Franco-EchevarrÃa E
(2022)
Plant vernalization proteins contain unusual PHD superdomains without histone H3 binding activity.
in The Journal of biological chemistry
Fiedler M
(2022)
Head-to-tail polymerization by VEL proteins underpins cold-induced Polycomb silencing in flowering control.
in Cell reports
Mattick J
(2023)
Long non-coding RNAs: definitions, functions, challenges and recommendations
in Nature Reviews Molecular Cell Biology
Studentship Projects
| Project Reference | Relationship | Related To | Start | End | Student Name |
|---|---|---|---|---|---|
| BB/M011216/1 | 30/09/2015 | 31/03/2024 | |||
| 1937483 | Studentship | BB/M011216/1 | 30/09/2017 | 29/09/2021 |
| Description | Visits to Laboratory of Molecular Biology, Cambridge |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Postgraduate students |
| Results and Impact | Mathias Nielson visited Laboratory of Molecular Biology to get training in specific protein biochemistry techniques and discuss research strategies |
| Year(s) Of Engagement Activity | 2019 |