Japan Partnering Award: Gene regulatory networks in stem cells and primordial germ cells
Lead Research Organisation:
University of Edinburgh
Department Name: Sch of Biological Sciences
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Publications
Zhang M
(2019)
Segregation of the mouse germline and soma.
in Cell cycle (Georgetown, Tex.)
Zhang J
(2018)
OTX2 restricts entry to the mouse germline
in Nature
Vojtek M
(2021)
Loss of Resf1 reduces the efficiency of embryonic stem cell self-renewal and germline entry.
in Life science alliance
Zhang M
(2018)
Esrrb Complementation Rescues Development of Nanog-Null Germ Cells.
in Cell reports
Corsinotti A
(2017)
Distinct SoxB1 networks are required for naïve and primed pluripotency.
in eLife
Mullin NP
(2017)
Distinct Contributions of Tryptophan Residues within the Dimerization Domain to Nanog Function.
in Journal of molecular biology
Di Giovannantonio LG
(2021)
Direct repression of Nanog and Oct4 by OTX2 modulates the contribution of epiblast-derived cells to germline and somatic lineage.
in Development (Cambridge, England)
Vojtek M
(2022)
Differential repression of Otx2 underlies the capacity of NANOG and ESRRB to induce germline entry.
in Stem cell reports