📣 Help Shape the Future of UKRI's Gateway to Research (GtR)

We're improving UKRI's Gateway to Research and are seeking your input! If you would be interested in being interviewed about the improvements we're making and to have your say about how we can make GtR more user-friendly, impactful, and effective for the Research and Innovation community, please email gateway@ukri.org.

Modernising resistance testing for an era of antimicrobial resistance

Lead Participant: PUBLIC HEALTH ENGLAND

Abstract

We seek to revolutionise high quality AMR testing in Public Health England (PHE) with cutting-edge new robotics for antimicrobial susceptibility testing (AST). The improved data reproducibility will set a new international standard, better support patient management with faster and more accurate results, and improve the information gained via surveillance programs. This supports PHE’s priority of providing robust laboratory-based surveillance of AMR (one of the goals of the UK 5-year AMR strategy). A new rapid AST platform will be installed in two PHE labs to provide new dimensions to AST data from healthcare-associated, high containment and biothreat organisms. Triangulation of automated high quality AST, genetic (Whole Genome Sequence based) AST results and the new data dimensions (above) will build a peerless understanding and knowledge base of AMR and create a showcase, next-generation AMR pheno- and genotyping facility that will be unparalleled globally. It will be a new gold-standard in AST that will encourage further collaboration with PHE from the academic, public and industrial sectors and benefit the UK’s reputation as a world leader for AMR detection and surveillance.

Lead Participant

Project Cost

Grant Offer

PUBLIC HEALTH ENGLAND £299,496 £ 299,496

Publications

10 25 50