Hardware accelerated data processing pipeline for proteomics

Lead Research Organisation: University of Sheffield
Department Name: Automatic Control and Systems Eng


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Hubbard, Simon; Jones, Andy (2009) Proteome Bioinformatics

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Coca D (2010) A high-performance reconfigurable computing solution for Peptide mass fingerprinting. in Methods in molecular biology (Clifton, N.J.)

Description Developed a web-based user software interface to enable fast processing (on specialized hardware architecture-FPGA) of MALDI-TOF mass spectrometry data for protein mass fingerprinting.
Exploitation Route Can be used to perform analysis of large MS data sets efficently.
Sectors Aerospace, Defence and Marine,Healthcare,Pharmaceuticals and Medical Biotechnology

Description This work has informed the development of new approaches for analyzing raw mass spectrometry data by Shimadzu.
First Year Of Impact 2011
Sector Pharmaceuticals and Medical Biotechnology
Impact Types Economic

Description TDRI
Amount £356,480 (GBP)
Funding ID BB/F004893/1 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 03/2008 
End 02/2012
Title Peptide mass fingerprinting server 
Description PC incorporating FPGA co-processing board for peptide mass fingerprinting. Web-based distributed software application which allows users to submit PMF data to be processed on the server and retrieve the results. 
Type Of Technology New/Improved Technique/Technology 
Year Produced 2008 
Impact No actual Impacts realised to date