Genetic markers for flesh quality in farmed fish

Lead Research Organisation: University of St Andrews
Department Name: Biology

Abstract

Genetic markers are widely used in livestock breeding programs to select animals with superior production traits, e.g. meat quality. Fish aquaculture is a global growth industry with farmed salmon now a major UK food export. Compared with traditional livestock, fish species are relatively undomesticated and the use of genetic markers to produce superior strains for farming is in its infancy. The aim of this follow-on funding project is to strengthen a patent application for single nucleotide polymorphisms markers in Atlantic salmon that were found to be significantly associated with superior fillet yield and improved flesh quality. Studies with larger populations of fish and of the association between the genetic polymorphisms and quality traits in families of known pedigree are required for the commercial validation of the markers. The project will also screen a pipeline of other genetic markers for enhanced flesh quality and extend the approach to other farmed fish species.

Publications

10 25 50
 
Description The project validated genetic assays to select Atlantic salmon with a higher meat yield. The genetic assays detect naturally occurring variations in the sequence of two genes involved with muscle accretion and breakdown. Using the assays offspring can be produced with 4% more fillet worth around £600 per tonne at current market prices. The work done on the grant strengthened a patent application and led to an investment and the formation of a spin-out company Xelect Ltd in February 2013. The company has subsequently licensed the technology to 2 major salmon breeding companies in Europe and Chile. Commercial trials are now well underway and we anticipate marketing of high yield fish and a royalty stream from 2017.
Exploitation Route Our research has led to a commercial project which is available for licensing to improve the profitability of salmon farming.
Sectors Agriculture, Food and Drink

URL http://www.bbsrc.ac.uk/news/food-security/2013/130318-pr-quality-fish-from-lab-to-plate.aspx
 
Description Our findings have been used to develop and successfully market genetic assays to select Atlantic salmon with a higher fillet yield. Currently licensees are SalmoBreed A/S and Landcatch Natural Selection. see also BBSRC Impact CASE study http://www.bbsrc.ac.uk/news/impact/salmon-genetics-technology-xelect-boosts-global-aquaculture-industry/
First Year Of Impact 2013
Sector Agriculture, Food and Drink
Impact Types Economic

 
Description SMART: SCOTLAND
Amount £100,000 (GBP)
Funding ID SMART/13/063 
Organisation Scottish Enterprise 
Sector Public
Country United Kingdom
Start 02/2014 
End 01/2015
 
Title FISH SELECTION FOR IMPROVED TRAITS BASED ON THE DETECTION OF SEQUENCE VARIATIONS IN GENES 
Description The present invention is based on the identification of a number of genetic markers that segregate, or are associated with flesh quality in fish. In particular, the inventors have determined that variations in the sequence of several genes are associated with flesh quality in fish. 
IP Reference WO2013054107 
Protection Patent application published
Year Protection Granted 2013
Licensed Yes
Impact Commercial validation trials are being conducted in Norway and Chile prior to the marketing of ova from high fillet yield lines in 2016.
 
Company Name Xelect Ltd 
Description Xelect develops and licensed genetic markers for broodstock selection in farmed fish. The company also provides a range of genetic services to the aquaculture industry worldwide. 
Year Established 2013 
Impact The company has licensed genetic assays for high fillet yield in Atlantic salmon and Nile Tilapia to major breeding companies in Europe, Chile and SE Asia.
Website http://www.xelect.co.uk/