Development of a high-throughput perfused three dimensional cell culture platform for stem cell study and drug testing

Lead Research Organisation: University of Oxford
Department Name: Engineering Science


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Description Through the project, we improved two aspects related to microbioreactor technology - (i) increased throughput, so to increase productivity, (ii) introduced automation, to make the equipment more user friendly. Case studies using different cell platforms were published to show the efficacy.
Exploitation Route Industry in Taiwan and China are exploring to commercialise the technology.
Sectors Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology

Description A new drug testing platform based on advanced cell based assays was established and ready to be used in industry. The project also promoted collaboration between UK and Taiwan.
First Year Of Impact 2014
Sector Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology
Impact Types Economic

Description MeStar 
Organisation Oxford MeStar Limited
Country United Kingdom 
Sector Private 
PI Contribution I/my team are conducting research projects in translational and regenerative medicine, in particular developing enabling technologies for stem cell therapy.
Collaborator Contribution My partner, Oxford MeStar Limited has contributed 90,000 pounds for research that develops enabling technologies for tissue engineering and stem cell therapy. This company has core technical expertise in bioprocessing, bioengineering and bio-manufacture.
Impact PMID: 24184152 PMID: 23977329 PMID: 21976446
Start Year 2013