Research visit to the Joint BioEnergy Institute CA

Lead Research Organisation: University of Glasgow


United States


10 25 50
Description The overarching aim was to develop new Synthetic Biology chassis strains for advanced metabolic engineering for production of biofuels and high value small molecules. In order to accomplish this as part of the proposed visit we demonstrated recombinase based gene deletion for metabolic pathway flux optimization. While at JBEI I learned cutting edge yeast synthetic biology techniques which I then took back to my own lab. As a result of this I developed projects in yeast synthetic biology which were subsequently funded in collaboration with industrial partners - Unilever and Croda funded by innovate UK. This initial grant also led on to a subsequent grant funded by the IBioIC. See funding section for details. In addition the contacts and academic discussions have been invaluable. The time away from my own lab environment allowed me to future focus rather than just dealing with the day to day.
Exploitation Route These preliminary findings have been used to develop projects with industrial collaborators such as Unilever and Croda.
Sectors Chemicals,Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology

Description 2014 Industrial Biotechnology Catalyst Round 2
Amount £440,217 (GBP)
Funding ID BB/M028860/1 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 04/2016 
End 04/2019
Description Industrial Biotechnology Innovation Centre - SynBio Accelerator project
Amount £200,393 (GBP)
Organisation IBioIC 
Sector Academic/University
Country United Kingdom
Start 05/2017 
End 05/2019
Title Novel methods for gene assembly 
Description We have developed (and are continuing to develop) new methods for rapid efficient assembly of DNA fragments using serine integrases. 
Type Of Material Technology assay or reagent 
Year Produced 2014 
Provided To Others? Yes  
Impact First version of the method is published (S.D. Colloms et al., Nucleic Acids Res. 42, e23).