Research visit to the Joint BioEnergy Institute CA
Lead Research Organisation:
University of Glasgow
Abstract
United States
People |
ORCID iD |
| Susan Rosser (Principal Investigator) |
Publications
Colloms SD
(2014)
Rapid metabolic pathway assembly and modification using serine integrase site-specific recombination.
in Nucleic acids research
| Description | The overarching aim was to develop new Synthetic Biology chassis strains for advanced metabolic engineering for production of biofuels and high value small molecules. In order to accomplish this as part of the proposed visit we demonstrated recombinase based gene deletion for metabolic pathway flux optimization. While at JBEI I learned cutting edge yeast synthetic biology techniques which I then took back to my own lab. As a result of this I developed projects in yeast synthetic biology which were subsequently funded in collaboration with industrial partners - Unilever and Croda funded by innovate UK. This initial grant also led on to a subsequent grant funded by the IBioIC. See funding section for details. In addition the contacts and academic discussions have been invaluable. The time away from my own lab environment allowed me to future focus rather than just dealing with the day to day. |
| Exploitation Route | These preliminary findings have been used to develop projects with industrial collaborators such as Unilever and Croda. |
| Sectors | Chemicals,Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology |
| Description | 2014 Industrial Biotechnology Catalyst Round 2 |
| Amount | £440,217 (GBP) |
| Funding ID | BB/M028860/1 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2016 |
| End | 04/2019 |
| Description | Industrial Biotechnology Innovation Centre - SynBio Accelerator project |
| Amount | £200,393 (GBP) |
| Organisation | IBioIC |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 05/2017 |
| End | 05/2019 |
| Title | Novel methods for gene assembly |
| Description | We have developed (and are continuing to develop) new methods for rapid efficient assembly of DNA fragments using serine integrases. |
| Type Of Material | Technology assay or reagent |
| Year Produced | 2014 |
| Provided To Others? | Yes |
| Impact | First version of the method is published (S.D. Colloms et al., Nucleic Acids Res. 42, e23). |