Exploiting synergies in barley research

Lead Research Organisation: University of Dundee
Department Name: School of Life Sciences

Abstract

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Description This is a partnering award that has allowed us to maintain and strengthen links with several groups in Australia. We have now published a raft of papers relating to genes involved in barley cell wall biosynthesis and a paper on transcriptional networks in the developing grain. The PI just received a collaborative award from the ARC (with Prof. Peter Langridge) that will extend their collaboration on recombination in large genome crops and have submitted an application to IWYP. The UUKi Rutherford fund will se a number of Australian ECRs from Perth, Sydney, Brisbane and Adelaide come to the university of Dundee for between 1 and 12 months. Several medium-high impact papers are being written for publication in peer reviewed journals and i expect these to emerge in press in the coming 12 months.
Exploitation Route I anticipate further bi-lateral exchange visits by young early career scientists in particular, with Matt Tucker proposing to visit and others from Rachel Burtons lab planning to spend some time in Dundee. the PDRA on the ARC discovery grant to myself and Peter Langridge will likely come to Dundee for 3 months in early summer 2018 and some of those from Dundee that have already benefitted from the award did return to complete work started when there previously (e.g. Ruth Hamilton).
Sectors Agriculture, Food and Drink,Education,Energy

 
Description Project has been extended and now has 10 months to go. Several members of the Dundee group (Houston, Zhang, Schreiber, Giminez, Waugh, Booth, Oakey, Hamilton) have benefitted from stays in Adelaide and Brisbane and R. Burton, M. Tucker, A. Hassan, G.Fincher, J. Schwerdt, P. Langridge, N. Betts, H. Collins time in Dundee. Further exchange visits are planned for the coming year. For everyone this has been a fantastic learning experience (especially the younger scientists) and we will build on these relationships to form new collaborations into the future. The relationships established over this period have led to Claire Halpin and I recently winning an UUKi Rutherford award worth £150K to allow ECRs from Australia to come and work in the UK for 1 - 12 months between march 2018 and march 2019
First Year Of Impact 2016
Sector Agriculture, Food and Drink,Education,Energy
Impact Types Economic

 
Description AHDB research call
Amount £65,000 (GBP)
Funding ID 21130015 Integrated platforms for barley breeding and genetic research (INTEGRA-2) 
Organisation Agricultural and Horticulture Development Board 
Sector Public
Country United Kingdom
Start 04/2016 
End 03/2017
 
Description ERC Advanced Grant
Amount € 2,500,000 (EUR)
Funding ID ERC-2014-ADG 669182 
Organisation European Research Council (ERC) 
Sector Public
Country European Union (EU)
Start 11/2016 
End 10/2020
 
Description UUKI Rutherford fund - strategic partner grants
Amount £150,000 (GBP)
Funding ID RF-2018-30 
Organisation Universities UK 
Sector Academic/University
Country United Kingdom
Start 03/2018 
End 03/2019
 
Description Barley Away Days 
Organisation University of Adelaide
Department School of Agriculture, Food and Wine
Country Australia 
Sector Academic/University 
PI Contribution We Hosted Prof Rachel Burton at our Barley Away Days in Dunkeld (3 day meeting) where she gave a talk about her latest research
Collaborator Contribution Rachel attended the BAD and interacted with students and postdocs. She gave an excellent presentation of current research in her group and judged the poster competition and short talks.
Impact Strengthened relationships with the cell walls group in Adelaide
Start Year 2017
 
Description CSLF activity 
Organisation University of Adelaide
Department School of Agriculture, Food and Wine
Country Australia 
Sector Academic/University 
PI Contribution Miriam Schreiber visited Adelaide for 2 months to test the activity of three new CslF genes she identified in the released barley genome assembly
Collaborator Contribution Hosted Miriam and taught her how to do transient assays in nicotiana and how to assay for mixed linkage beta glucan
Impact Outputs listed as Schreiber et al under BB/J014869/1 outputs
Start Year 2014
 
Description Cell Walls 2 
Organisation University of Adelaide
Department School of Agriculture, Food and Wine
Country Australia 
Sector Academic/University 
PI Contribution Kelly Houston spent 1 month in Adelaide completing work for a paper, interacting with joint students and planning further collaborative research
Collaborator Contribution Rachel Burton and Matt Tucker hosted Kelly Houston in Adelaide and worked on completing work for a paper, interacting with joint students and planning further collaborative research.
Impact paper outputs are listed under the submission for BB/J014869/1
Start Year 2014
 
Description Cell walls 1 
Organisation University of Adelaide
Department School of Agriculture, Food and Wine
Country Australia 
Sector Academic/University 
PI Contribution Kelly Houston spent 3 months in Adelaide in 2015 and 1 month in 2017. The visits allowed us to extend collaborative work on barley plant cell walls. New Joint Student between Kelly Houston (Dundee) and Matt Tucker/Rachel Burton (Adelaide) has recently been awarded.
Collaborator Contribution Hosted Kelly, gave access to all research facilities and resources, Jointly formulated PhD position, shared materials for joint publications
Impact We have published many joint papers listed under outputs of BB/J014869/1. We have collaborative grants currently under consideration in both UK (BBSRC) and Australia (ARC)
Start Year 2015
 
Description Centre of Excellence 
Organisation University of Melbourne
Department The Peter Cook Centre for Carbon Capture and Storage Research
Country Australia 
Sector Academic/University 
PI Contribution RW visited the Annual Cell Walls Conference in Hahndorf, gave a talk and planned joint research proposal for ARC.
Collaborator Contribution Joint sharing of unpublished data, writing ARC grant application with Houston and Waugh as Co-I's
Impact Grant submitted to ARC in Feb 2017
Start Year 2016
 
Description Exploiting synergies 
Organisation University of Adelaide
Department School of Agriculture, Food and Wine
Country Australia 
Sector Academic/University 
PI Contribution I jointly wrote a grant with Peter Langridge to ARC as a Co-Investigator. It was funded this year but has not yet started. We did this remotely and during face to face meetings in both Adelaide (funding for me by this award) and Europe (funding for Langridge from Adelaide)
Collaborator Contribution We jointly conceived and wrote the applicatioin
Impact A AU$570,000 ARC Grant to look at aspects of meiosis and recombination in wheat and barley
Start Year 2016
 
Description Network analysis 
Organisation University of Adelaide
Department School of Agriculture, Food and Wine
Country Australia 
Sector Academic/University 
PI Contribution Collaboration was to develop an understanding of gene networks involved in very early grain development - with a particular focus on the cellularisation of the barley endosperm. We did microarray and network analysis
Collaborator Contribution Provision of v. early cellular material, validation (qPCR) and biological interpretation of cellular networks, particularly in relation to the newly forming cell wall.
Impact Nice paper in Plant Physiology http://www.plantphysiol.org/content/170/3/1549.full.pdf
Start Year 2014
 
Description Phylogeny 
Organisation University of Adelaide
Department School of Agriculture, Food and Wine
Country Australia 
Sector Academic/University 
PI Contribution We trained and assisted Julian Schwerdt from Adelaide on Phylogenetic analysis
Collaborator Contribution Julian made several visits to Dundee where he worked with Houston, Marshall, Wright and Waugh on establishing robust sequence based molecular phylogenies
Impact http://www.plantphysiol.org/content/early/2015/05/21/pp.15.00140 Paper published from outcome of collaboration
Start Year 2014
 
Description Recombination in wheat and barley 
Organisation University of Adelaide
Department School of Agriculture, Food and Wine
Country Australia 
Sector Academic/University 
PI Contribution I was a Co-Investigator on a successful ARC discovery grant on meiosis and recombination in wheat and barley with Prof. Peter Langridge. The award will use resources generated in my research program for mutual benefit. It was developed largely through the funding awarded for an Australia partnering award which has seen multiple visits in each direction over the past 4 years.
Collaborator Contribution The partners will receive ALL of the funding save some money for travel to meetings throughout the project. The partners will provide lab, consumables funding and all administrative resources required to execute the project objectives. The funding allows the University of Adelaide to employ a PDRA and technician for three years.
Impact Still too early. Project only started a few months ago.
Start Year 2017
 
Description Speed Breeding 
Organisation University of Queensland
Country Australia 
Sector Academic/University 
PI Contribution Allan Booth (Dundee) spent three months working with Lee Hickey in UQ to learn the speed breeding technique (barley seed to seed in 60 days. He has now established a parallel facility in Dundee and this is being incorporated into on going projects and funding applications
Collaborator Contribution Lee hosted Allan for 3 months and kindly shared all steps of the speed breeding approach.
Impact Implementation of Speed Breeding in Dundee University and JHI
Start Year 2016
 
Description Student Placement 
Organisation University of Adelaide
Department School of Agriculture, Food and Wine
Country Australia 
Sector Academic/University 
PI Contribution Joint PhD student Guillermo Giminez spent 3 months working in the group of Matt Tucker in the cell walls centre of excellence building reported gene constructs for transformation and testing them in vivo
Collaborator Contribution Direct supervision of Guillermo in building reported gene constructs for transformation and how to test them in vivo
Impact Guillermo is still pursuing his PhD. Publications are planned but not yet written.
Start Year 2014