Towards an understanding of cytoskeletal dynamics: coupling systematic fly genetics with computational modelling
Lead Research Organisation:
University of Manchester
Department Name: School of Biological Sciences
Abstract
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Publications
De Moura, Carlos
Computational modeling of cytoskeletal dynamics through particle-in cell
in XVII Convención de Ingeniería y Arquitectura (CCIA-14) - ISBN 978-959-261-467-3
Leal, T. F.
(2018)
Plasmatic membrane response to actin filaments dynamics
Pearce S
(2017)
Microtubule Curling
Pearce S
(2017)
Microtubule Rings
Pearce S
(2017)
Modelling Microtubule Rings
Pearce S
(2017)
Modelling Microtubule Rings
Pearce SP
(2018)
Curvature-Sensitive Kinesin Binding Can Explain Microtubule Ring Formation and Reveals Chaotic Dynamics in a Mathematical Model.
in Bulletin of mathematical biology
Pearce, S. P.
(2015)
A mathematical model of neuronal axon loss in ageing and neurodegeneration
Description | A novel concept for filopodial dynamics. The mathematical model has now been shown to work and publication is being prepared. |
Exploitation Route | I am member of a new Wellcome Trust PhD scheme of quatitative biology within the framework of which we continue to work on this problem. The OOP strategy of programming offers new opportunities to biological modelling. |
Sectors | Digital/Communication/Information Technologies (including Software),Education |
URL | http://www.springer.com/cda/content/document/cda_downloaddocument/9783319388687-c2.pdf?SGWID=0-0-45-1580468-p179979730 |
Description | A mathematical model of neuronal axon loss in ageing and neurodegeneration |
Amount | £150,000 (GBP) |
Funding ID | ECF-2015-229 |
Organisation | The Royal Society |
Department | Royal Society Leverhulme Trust Senior Research Fellowship |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 07/2015 |
End | 06/2018 |