Releasing natural variation in bread wheat by modulating meiotic crossovers

Lead Research Organisation: University of Bristol
Department Name: Biological Sciences

Abstract

In bread wheat, important agronomical traits are distributed along chromosomes. Traditionally, plant breeders cross high yielding parental lines and then select for progeny in subsequent generations that carry desirable attributes whist removing undesirable traits. However, the process of 'gene-shuffling' (meiotic recombination) is non-random and skewed towards the ends of the chromosomes. Therefore, desirable traits are often transmitted as a block together with undesirable traits. This is analogous to dealing a deck of cards where a significant proportion of the cards are tethered by an elastic band. In this case a desirable hand cannot be achieved until the elastic band is severed and the cards are able to segregate freely. In this proposal we aim to understand why desirable and undesirable traits in bread wheat are often tethered together, so that we can break this bond, and release the full potential of available natural variation. Then, we aim to modulate this process so that the plant breeder can decide which traits can be 'dealt' together in the same variety. This unlocking of wheat's natural variation will lead to the production, via classical plant breeding, of superior varieties with favourable agronomic traits such as increased yield and improved nutrient acquisition.

To provide direct evidence that our research has application we will work with two of the UK's largest wheat breeders KWS and RAGT to target chromosomal regions, which are known to be transmitted as blocks. We will show that by using novel procedures, we can increase the amount of recombination in these blocks. Increasing the amount of recombination in any of these regions will enable breeders to generate new gene combinations which will lead to new varieties with, for instance, increased protein content or pathogen resistance. Further down the breeder's pipeline our research will directly translate to new varieties with superior characteristics that will help maintain farm incomes and improve sustainability of the UK arable and milling industries. In addition high yielding varieties will reduce dependence on imported grain and associated transport and environmental costs and improved pipelines for the generation of new UK varieties that will enhance reliability and competitiveness in overseas markets.

Technical Summary

Meiotic recombination generates new alleles and new allelic combinations. Together with the ability of the wheat breeder to select desirable traits, the formation of new alleles and new allelic combinations determines the rate at which improved varieties are generated and they determine the extent of genetic gain. The products of recombination can be classified as being the result of crossovers (COs) or gene conversion. While both result in the formation of new alleles, CO's are essential for the formation of new allelic combinations. Unfortunately, in many species, COs are restricted in number (in wheat there are 1-3 per chromosome pair) and they are skewed in distribution to regions near the ends of chromosomes. As a result an estimated 30-50% of genes reside in recombination 'cold' regions. This creates the problem of linkage-drag in the cold centromere-proximal and interstitial regions where undesirable variation cannot be separated from useful traits. In effect, these regions become inaccessible to researchers and breeders alike. Thus, it is essential that we develop methods to manipulate the frequency and distribution of COs in species such as bread wheat and therefore aid the breeders in the generation of novel allelic combinations.

The aim of our five year work programme is to build upon our recent studies, and identify and modify the factors controlling CO frequency and distribution during meiosis via a range of complementary genetic and cytogenetic approaches. This knowledge will be used to manipulate CO formation in wheat, using synthetic approaches and targeting recombination using both a transgenic and non-transgenic approach.

Development of a set of tools and procedures which can be employed to manipulate both the rate and location of COs would revolutionise wheat breeding and they would lead to the rapid developments of a range of elite lines derived from novel germplasm.

Planned Impact

Recombination is important to the UK wheat harvest because recombination drives plant breeding. The generation, selection and characterisation of new allelic combinations are essential if wheat breeders are to develop new varieties with superior traits. Unfortunately, plant breeders have no control as to where recombination occurs and therefore regions with little or no recombination are effectively excluded from the breeding process. Genes in areas devoid of recombination generate few novel allele combinations and therefore have a propensity to become fixed within breeding populations. Breaking such linkage blocks is a significant target for wheat breeders, and would unlock a wealth of untapped genetic variation. Thus, research that leads to such 'breakage' will have a dramatic economic impact on the breeding industry, farmers and society, who consume the wheat crop.

Social impact over the timescale of the project will be achieved by dissemination of the results through peer reviewed journal publication as well as oral and poster presentations at national and international scientific conferences. Information generated by the program will be made available via CerealsDB, which has recently been funded by the BBSRC until at least 2018. The importance of the project will be highlighted during university open days as well as outreach collaborations such as the NIAB Innovation Farm. The economic impact over the timescale of the project will include benefits to the suppliers of scientific materials in the UK. The main benefits to the UK economy will come at the latter stages of the project and when outputs are translated into novel elite varieties.

In the BBSRC 5-year wheat research strategy point 37 describes the 'need for succession planning and new blood', as there is a risk that as senior wheat researchers approach retirement age there are few obvious successors to cover the broad spectrum of areas encompassing wheat research. A sustainable plan for maintaining and augmenting wheat research capability is required to ensure a continued stream of innovation in the sector and supply of key skills to industry. Our project will take advantage of 1. The molecular and genetic experience in wheat from the PI Prof Edwards and co-investigator Dr Uauy and 2. The molecular and cytogenetic skills of co-investigator's Prof Franklin and Dr's Higgins, Henderson and Sanchez-Moran, to train the next generation of wheat geneticists/molecular cytogeneticists, at the post-graduate and post-doctoral level, in a range of skills and knowledge from the model plant Arabidopsis to wheat and vice versa.

Who will benefit from the increased skills and capacity? 1. Farmers, plant breeders, millers/bakers: Establishing procedures to generate new combinations for key genomic regions conferring, for instance, drought or insect resistance will enable wheat breeders to generate and select improved lines from elite UK germplasm. When translated to new varieties with superior characteristics this will help maintain farm incomes and improve sustainability of the UK arable and milling industries. In addition this will reduce dependence on imported grain and associated transport and environmental costs. Improved pipelines for the generation of new UK varieties will enhance reliability and competitiveness in overseas markets. 2. Scientists and plant breeders: Identification of biological processes linked to recombination will have a major impact on UK researchers who work with UK plant breeders to generate novel lines carrying a number of useful traits.

Publications

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publication icon
Burridge AJ (2017) High-Density SNP Genotyping Array for Hexaploid Wheat and Its Relatives. in Methods in molecular biology (Clifton, N.J.)

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Choi K (2017) Quantification and Sequencing of Crossover Recombinant Molecules from Arabidopsis Pollen DNA. in Methods in molecular biology (Clifton, N.J.)

 
Description In wheat, the exchange of genetic material (recombination) during meiosis is restricted to 1-3 per chromosome and the events are skewed in distribution to regions near the ends of the chromosomes. As a result an estimated 30-50% of genes reside in recombination 'cold' regions. This creates the problem of linkage-drag in the cold centromere-proximal and interstitial regions where undesirable variation cannot be separated from useful traits. In effect, these regions become inaccessible to breeders. Thus, it is desirable to manipulate the frequency and distribution of recombination in bread wheat to generate novel allelic combinations.

Via the strategic lola, we have identified and modified several of the factors controlling recombination frequency and distribution during bread wheat meiosis via complementary genetic and cytogenetic approaches. The knowledge gained has already been published in several high impact journals and is currently being used, in collaboration with industry, in a Follow-on-Fund program to manipulate recombination using a synthetic approaches to targeting recombination, using for instance a modified gene editing approach. We believe that by working with the wheat breeders we should, with a few years, be able to target recombination to specific regions of the genome and hence unlock the full potential for yield gains in the UKs most important crop.
Exploitation Route While our work on studying and manipulating wheat recombination is ongoing, overall, our findings to date have significant relevance for wheat improvement through the deployment of genetic or epigenetic manipulations aimed at increasing crossover rates in recombination-suppressed chromo some compartments. For instance our work points to the facultative heterochromatic marker H3K27me3 as a potential target for increasing crossovers. This together with the deployment of various mutants such as fancm, msh4/5 and spo11-1, together with chromatin modifications could be combined with trans-acting loci that direct crossovers to various, currently recombination-cold spot regions, which have been mapped in wheat.
Sectors Agriculture, Food and Drink,Manufacturing, including Industrial Biotechology

 
Description Meiotic recombination generates genetic variation and provides physical links between homologous chromosomes (crossovers) essential for accurate segregation. In wheat we have shown that the distribution of crossovers, cytologically evident as chiasmata, is biased toward the distal regions of chromosomes. This creates a bottleneck for breeders in the development of varieties with improved agronomic traits, as genes situated in the interstitial and centromere proximal regions of chromosomes rarely recombine. As a basis for our early investigations, we carried out a detailed analysis of meiotic progression in hexaploid wheat (Triticum aestivum) using immunolocalization of chromosome axis, synaptonemal complex and recombination proteins. 5-Bromo-2'-deoxyuridine (BrdU) labelling was used to determine the chronology of key events in relation to DNA replication. Axis morphogenesis, synapsis and recombination initiation were found to be spatio-temporally coordinated, beginning in the gene-dense distal chromosomal regions, and later occurring in the interstitial/proximal regions. Moreover, we have found that meiotic progression in the distal regions was coordinated with the conserved chromatin cycles that are a feature of meiosis. This mirroring of the chiasma bias was also evident in the distribution of the gene-associated histone marks, H3K4me3 and H3K27me3; the repeat-associated mark, H3K27me1; and H3K9me3. Within the slola this study provided a cytogenetic framework for functional studies and ongoing initiatives to manipulate recombination in the wheat genome. In connection with the above we went on to identify a number of genes which evidence suggested might be useful in the manipulation of recombination in wheat. However, it should be noted that our research also indicated that the details of meiosis were significantly different in polyploid wheat compared to model species such as Arabidopsis and yeast. For once such gene, FANCM we have shown that wheat fancm mutants exhibited a reduction in fertility (36% in tetraploid and 15% in hexaploid wheat), due to loss of the obligate chiasma. This was consistent with a previous study utilising FANCM-VIGS on tetraploid wheat F1 hybrids that showed a significant reduction in fertility, but no differences in recombination on chromosome 1A53. The immunohistochemistry, cytological and molecular marker analysis revealed that loss of class I COs was offset by an increase of class II COs in the tetraploid, thus resulting in no net change. However, fewer HEI10 foci were reduced in the hexaploid wheat fancm mutants, compared to the tetraploid, leading to an overall increase of COs by 31%. Based on an increase of class II chiasmata detected in the tetraploid, it is likely that the increase in COs in the hexaploid arose via the class II CO pathway. The molecular marker data revealed that COs increased in the majority of intervals tested, thus providing an opportunity to modulate recombination in wheat breeding programs. Our data also revealed an association between the difference in wild type and fancm COs with DNA methylation, H3K27me1 and H3K27ac, suggesting that the chromatin environment influences this process and may provide a suitable target to modulate the position of additional COs. In addition, we have shown that allotetraploid (AABB) durum wheat (Triticum turgidum ssp. durum) utilizes two pathways of meiotic recombination. The class I pathway requires MSH4 and MSH5 (MutSg) to maintain the obligate CO/chiasma and accounts for ;85% of meiotic COs, whereas the residual ;15% are consistent with the class II CO pathway. Class I and class II chiasmata are skewed toward the chromosome ends, but class II chiasmata are significantly more distal than class I chiasmata. Chiasma distribution does not reflect the abundance of double-strand breaks, detected by proxy as RAD51 foci at leptotene, but only; 2.3% of these sites mature into chiasmata. MutSg maintains the obligate chiasma despite a 5.4-kb deletion in MSH5B rendering it non-functional, which occurred early in the evolution of tetraploid wheat and was then domesticated into hexaploid (AABBDD) common wheat (Triticum aestivum), as well as an 8-kb deletion in MSH4D in hexaploid wheat, predicted to create a non-functional pseudogene. Stepwise loss of MSH5B and MSH4D following hybridization and whole-genome duplication may have occurred due to gene redundancy (as functional copies of MSH5A, MSH4A, and MSH4B are still present in the tetraploid and MSH5A, MSH5D, MSH4A, and MSH4B are present in the hexaploid) or as an adaptation to modulate recombination in allopolyploid wheat. Finally, to understand the role that SPO11-1 plays in double strand break formation and as a prelude to its manipulation, we have used CRISPR/Cas9 to generate hexaploid wheat plants carrying edits in all three wheat SPO11-1 homoeologous genes. Characterisation of progeny derived from these lines shows that, while plants deficient in all six SPO11-1 gene copies are sterile, lines carrying just a single copy of any one of the three homoeologous are phenotypically indistinguishable from unedited plants both in terms of their growth and fertility. However, surprisingly, cytogenetic analysis of the edited plants suggests differences in the ability of the individual homoeologous to generate double strand breaks. In addition, we further show that direct transformation of sterile wheat plants, carrying six edited copies of TaSPO11-1, with an 8.3 kb fragment carrying the entire B-genome SPO11-1 gene, restores SPO11-1 activity and fertility. While our work on studying and manipulating wheat recombination is ongoing, overall, our findings to date have significant relevance for wheat improvement through the deployment of genetic or epigenetic manipulations aimed at increasing crossover rates in recombination-suppressed chromosome compartments. Our work also points to the facultative heterochromatic mark H3K27me3 as a potential target for increasing crossovers. Chromatin modifications could be combined with trans-acting loci that direct crossovers to interstitial regions, which have recently been mapped in wheat.
First Year Of Impact 2021
Sector Agriculture, Food and Drink,Environment,Manufacturing, including Industrial Biotechology
Impact Types Societal,Economic,Policy & public services

 
Description Bioinformatics Training Workshop pre-Monogram
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
Impact Bioinformatics Traning Workshop pre-Monogram
 
Description Problems caused by introgessions
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
Impact Wheat breeding companies were made aware about the effect that introgressions have on recombination and why this may lead to difficulties in the future, this has caused some companies to re-examine their breeding strategies
 
Description Visit by Adam Stains, Matt Freeman and Harriet Trewin, BBSRC: Discussion on latest developments in crop breeding techniques
Geographic Reach National 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Visit by Green Party Norfolk County Councillors
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Visit from Government Office of Science (Nancy Bailey, Neil Waby, Rebecca Nohl)- Discussion on CRISPR gene editing
Geographic Reach National 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Visit of Norman Lamb MP
Geographic Reach National 
Policy Influence Type Influenced training of practitioners or researchers
 
Description A pipeline for efficient recombination in wheat
Amount £200,364 (GBP)
Funding ID BB/W003317/1 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 09/2021 
End 03/2023
 
Description BBSRC Flexible Talent Mobility Award (FTMA)
Amount £25,000 (GGP)
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 07/2019 
End 12/2019
 
Description International workshops
Amount £10,000 (GBP)
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 06/2019 
End 08/2019
 
Title Breeders tool kit meeting 
Description Novel wheat lines and novel wheat molecular markers to be transferred to the commercial sector 
Type Of Material Biological samples 
Year Produced 2018 
Provided To Others? No  
Impact Novel materials and markers to be supplied to the wheat breeding community 
 
Title New markers and new genotyping platform for wheat breeding 
Description New Axiom markers for use in wheat breeding 
Type Of Material Technology assay or reagent 
Year Produced 2017 
Provided To Others? Yes  
Impact New markers and new GbyS genotyping platform for screening and genotyping wheat 
 
Title Use of Virus Induced Gene Silencing (VIGS) to down-regulate meiosis genes 
Description In collaboration with Dr Kostya Kanyuka (Rothamsted Research) we have applied the VIGS approach to transiently down-regulate meiosis genes in wheat. This provides a rapid means of testing the meiotic phenotype by altering expression of particular genes of interest. This is can be achieved in less than a month, compared to CRISPR/Cas and TILLING that takes 6-12 months. 
Type Of Material Biological samples 
Year Produced 2017 
Provided To Others? No  
Impact Other research groups are now considering adopting our VIGS strategy. 
 
Title CerealsDB 
Description The CerealsDB web-site was created by members of the Functional Genomics Group at the University of Bristol. The site provides a range of facilities for the study of the wheat genome. The site has been designed with breeders in mind, and we hope that is will be easy and straightforward to use. 
Type Of Material Database/Collection of data 
Year Produced 2017 
Provided To Others? Yes  
Impact There have been over 1,528,817 unique visits to the websites and our various datasets have been downloaded 48,295 times (35K Wheat breeders Array: 45,445 downloads and 820K High Density Wheat Array; 2,850 downloads). The trend of increased numbers of researchers visiting our web site shows no sign of slowing down; running as it is at greater than 50,000 unique visits per month. 
URL http://www.cerealsdb.uk.net/
 
Title Introgression plotter added to Cerealsdb 
Description Software to allow users to screen wheat germplasm for potential introgressions from wheat relative 
Type Of Material Data analysis technique 
Year Produced 2019 
Provided To Others? Yes  
Impact At the request of the wheat breeding companies we have made this tool available via Cerealsdb so that breeders can check on the presence of possible introgressed regions in the bread wheat genome 
 
Title QTL database 
Description Upload of QTL database to Cerealsdb 
Type Of Material Data analysis technique 
Year Produced 2019 
Provided To Others? Yes  
Impact Breeders and academics are now able to download/examine various QTL-based datasets 
 
Title Upgrade to cerealsdb (cerealsdb3) 
Description We have carried out a significant upgrade of cerealsdb to include new analytical tools and a much larger data set 
Type Of Material Database/Collection of data 
Year Produced 2019 
Provided To Others? Yes  
Impact Increased level of data downloads and use of tools to detect introgressions in wheat 
URL http://www.cerealsdb.uk.net/cerealgenomics/CerealsDB/indexNEW.php
 
Description Collaboartion with Syngenta to exchnage knowledge on trasformation and double haploid production 
Organisation Syngenta International AG
Department Syngenta Ltd (Bracknell)
Country United Kingdom 
Sector Private 
PI Contribution exchange of personal to improve our technology in double haploid production
Collaborator Contribution Spent time at Syngenta providing input into transformation technolgy
Impact Better transformation and double haploid technology available to Bristol
Start Year 2019
 
Description KWS 
Organisation KWS UK
Country United Kingdom 
Sector Private 
PI Contribution Genetics and genomics
Collaborator Contribution Breeder know how and germplasm
Impact joint projects
Start Year 2009
 
Description Leicester collaboration with Earlham Institute. James Higgins and Anthony Hall (Earlham Institute) have collaborated through this grant and have recently published a paper on recombination in wheat in Genome Biology (see publication list) 
Organisation Earlham Institute
Country United Kingdom 
Sector Academic/University 
PI Contribution The Leicester research team provided a cytological analysis to determine the number of recombination initiation sites in wheat.
Collaborator Contribution The Earlham institute provided QTL analysis to identify RECQ7 as a gene influencing gene conversion and crossover formation in wheat.
Impact BB/T011963/1 TRDF grant
Start Year 2018
 
Description RAGT 
Organisation RAGT Seeds
Country United Kingdom 
Sector Private 
PI Contribution Genetics and genomics
Collaborator Contribution Wheat germplasm and know how
Impact Shared projects
Start Year 2009
 
Title METHODS TO INCREASE MEIOTIC CROSSOVER FREQUENCY IN PLANTS 
Description The invention relates to methods and agents for increasing the frequency of crossover events during meiosis in plant cells. For this purpose, the method comprises the step of increasing the activity and/or levels of an HEI10 protein in the plant cell. 
IP Reference WO2018104724 
Protection Patent application published
Year Protection Granted 2018
Licensed Commercial In Confidence
Impact We recently published a follow-up publication combining HEI10 with recq4a recq4b mutations to further additively increase crossovers (Serra et al., 2018 PNAS).
 
Description A-Level Outreach workshop 'Meiosis and the Generation of Variation' 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact An outreach workshop was designed for Year 12/13 A-Level students to communicate some of the science involved in the project and it's potential impact. The workshop entitled 'Meiosis and the Generation of Variation' consisted of short talks, given by the project partners, and lots of experimental work for the students. This was offered to schools on the University's widening participation list. The workshops were attended by 30 students (plus teachers) and repeated the following day for an extra cohort of students. Following each workshop we gained feedback from students and staff. From this 94% of the students said that their knowledge of meiosis had increased and 88% understood that increasing the genetic variation of crop plants was important for food security. Comments from students/teachers:
• 'The students really enjoyed it and were amazed by the complexities of the subject' (Student, 2018).
• 'I enjoyed learning about current research and CRISPR-Cas 9 - that was really interesting' (Student, 2018).
• 'We would be keen for this again next year or anything similar you plan as it really is a great way to enrich the students and really stretch & challenge them' (Teacher, 2018).
The following link is to a blog written by one of the schools attending the 2019 workshop in Cambridge: https://www.longroad.ac.uk/noticeboard/modifying-dna-with-cambridge-university/
Year(s) Of Engagement Activity 2018,2019
URL https://biologicalsciences.blogs.bristol.ac.uk/2018/05/31/plant-science-outreach-meiosis-and-the-gen...
 
Description Academic visitor from the University of Salamanca 3/9/2018 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Academic visit from Javier Bobo Pinilla of the University of Salamanca. Visit was for training, data sharing and discussion of future collaboration opportunities
Year(s) Of Engagement Activity 2018
 
Description Bristol Plant Science Workshop, 2018-10-17 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Postgraduate students
Results and Impact Amanda Burridge attended the Bristol Plant Science Workshop and presented 'Using Ancient Grains to Improve Modern Bread Wheat'
Year(s) Of Engagement Activity 2018
 
Description British Meiosis Meeting Aberyswyth 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact British meiosis meeting in Aberystwyth
Year(s) Of Engagement Activity 2019
URL https://www.aber.ac.uk/en/ibers/news/events/britishmeiosismeeting/
 
Description CIMMYT visit to IWYP material Field Trials 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Amanda Burridge visited the Obregon CIMMYT site, specifically field sites used for IWYP projects.
Year(s) Of Engagement Activity 2017
 
Description Cereals 2017 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Indian delegates training at the University of Bristol were taken to 'Cereals 2017' in Boothby Graffoe, Lincolnshire to meet other researchers, farmers, breeders etc
Year(s) Of Engagement Activity 2017
 
Description Cereals Event 2020 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Cereals Event talk on plant breeding technologies
Year(s) Of Engagement Activity 2020
 
Description Cibus 2018, Salone internazionale dell'alimentazione 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact Cibus 2018, Salone internazionale dell'alimentazione
Year(s) Of Engagement Activity 2018
 
Description Co-Higgins is a member on the Research Oversight Committee for the Canadian Triticum Applied Genomics grant 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact For the large CTAG2 Canadian grant, advice is given about past and future experiments.
Year(s) Of Engagement Activity 2015,2016,2017,2018
URL https://www.genomecanada.ca/en/canadian-triticum-applied-genomics-ctag2
 
Description Conference Madrid 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact ITN meeting in El Escorial, Madrid June 2019 invited external speakers from academic and industry (plant breeders) talks about where meiosis recombination research is going in the future.
Year(s) Of Engagement Activity 2019
URL https://meicom-itn.com/meetings
 
Description Crop Genetics workshop 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact A workshop on nitrogen use efficiency and wheat genetics was held in New Delhi from 25th Feb-1st March 2019 for 20 Indian undergraduate and postgraduate students.
Year(s) Of Engagement Activity 2019
 
Description Discussion on gene editing and regulations with BSPB, Royal Society, UKPSF, breeders 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact Discussion on gene editing and regulations with BSPB, Royal Society, UKPSF, breeders
Year(s) Of Engagement Activity 2020
 
Description Discussion on gene editing with NFU East Anglia (full membership) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Discussion on gene editing with NFU East Anglia complete membership
Year(s) Of Engagement Activity 2021
 
Description Discussion on gene editing with NFU East Anglia Crop Board 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Policymakers/politicians
Results and Impact Discussion on gene editing with NFU East Anglia Crop Board
Year(s) Of Engagement Activity 2021
 
Description Discussion on gene editing with NFU East Midlands 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Policymakers/politicians
Results and Impact Discussion on gene editing with NFU East Midlands
Year(s) Of Engagement Activity 2021
 
Description Discussion on gene editing with NFU National Crops Board 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Discussion on gene editing with NFU National Crops Board
Year(s) Of Engagement Activity 2021
 
Description Discussion on gene editing with NFU National Regional Crops Board 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Discussion on gene editing with NFU National Regional Crops Board
Year(s) Of Engagement Activity 2021
 
Description Discussion on gene editing with NFU South West 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Policymakers/politicians
Results and Impact Discussion on gene editing with NFU South West
Year(s) Of Engagement Activity 2021
 
Description Discussion on gene editing with NFU West Midlands 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Policymakers/politicians
Results and Impact Discussion on gene editing with NFU West Midlands
Year(s) Of Engagement Activity 2021
 
Description Engagement with industry 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Meeting with technology provider regarding a new genotyping platform and its application
Year(s) Of Engagement Activity 2017
 
Description Engagement with industry 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Meeting with service providers for genotyping technical development
Year(s) Of Engagement Activity 2017
 
Description Engagement with industry 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Discussion with technology provider regarding optimisation of new technology for wheat
Year(s) Of Engagement Activity 2018
 
Description Engagement with industry 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Discussion with breeder regarding marker development for tracking introgressions
Year(s) Of Engagement Activity 2017
 
Description Engagement with industry 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Transfer of markers to technology provider to aid the development of a new genotyping platform
Year(s) Of Engagement Activity 2017
 
Description Engagement with industry 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Germplasm exchange for technical development
Year(s) Of Engagement Activity 2017
 
Description Exchange visit from Mohammed Shamshad, Punjab Agricultural University 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Mohammed visited the University of Bristol in September and October 2018 where he was trained in lab-based genotyping and bioinformatics. He participated fully in group meetings and gave a seminar in the Life Sciences building describing his project.
Year(s) Of Engagement Activity 2018
 
Description From Seed to Pasta III, Bologna, Italy, 2018-09-19 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Amanda Burridge attended and met delegates from From Seed to Pasta III, a conference that focused on durum wheat breeding and processing.
Year(s) Of Engagement Activity 2018
 
Description GARNet Gene Editing Workshop 26 -27 March 2018 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Plant gene editing workshop held at Bristol University.
Year(s) Of Engagement Activity 2018
 
Description Garnet York 2018 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Garnet York 2018
Year(s) Of Engagement Activity 2018
 
Description Gave seminar at Warwich University 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact The talk sparked questions and discussion afterwards with both academics and students.

After my talk I set up a collaboration with a researcher at Warwick.
Year(s) Of Engagement Activity 2015
 
Description German Plant Breeding Society 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact German Plant Breeding Society: keynote
Year(s) Of Engagement Activity 2020
 
Description INEW meeting attendance - London - 14/09/2018 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact Amanda Burridge and Sacha Przewieslik-Allen attended the annual review meeting for INEW. Data handling was discussed with plans made for future activities with co-ordinated experimental design. Plans were discussed for future training opportunities.
Year(s) Of Engagement Activity 2018
 
Description INEW meeting, London Sept 2018 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact Alexandra Przewieslik-Allen attended an INEW review meeting, London September 2018
Year(s) Of Engagement Activity 2018
 
Description IWGSC Webinar 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact IWGSC Webinar on new genomic tools in wheat
Year(s) Of Engagement Activity 2020
 
Description International Computation Biology Society: Africa meeting 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact International Computation Biology Society: Africa meeting
Year(s) Of Engagement Activity 2019
 
Description Invited Speaker for Society for Experimental Biology Annual Main Meeting Antwerp from June 29th - 2nd July 2021 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited speaker to SEB in Artwenp but now changed to an online meeting via Zoom.
Year(s) Of Engagement Activity 2021
URL https://www.sebiology.org/events/event/seb-conference-2021
 
Description Invited Talk at PAG XXV San Diego 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Research talk at the Cytogenetics workshop. Excellent questions and participation that showed a clear interest by different sectors (research and plant breeding companies). Title: "Control of meiotic recombination by the phosphorylation of ASY1" Authors: Heckman S, Martinez-Garcia M, West A, Osman K, Franklin C & Sanchez-Moran E. 2017
Year(s) Of Engagement Activity 2017
URL http://www.intlpag.org/
 
Description Invited seminar (Indian Agricultural Research Institute) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Invited talk on "Developments in wheat genetics and genotyping" at Indian Agricultural Research Institute including a detailed Q&A and visits to a number of key departments to discuss future collaborative opportunities.
Year(s) Of Engagement Activity 2016
 
Description JIC Open day 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact JIC Open Day
Year(s) Of Engagement Activity 2018
 
Description Jersey Farming Conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Jersey Farming Conference
Year(s) Of Engagement Activity 2019
 
Description Jesus College, Cambridge conference on Food, Farming and Climate Change 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Jesus College, Cambridge conference on Food, Farming and Climate Change
Year(s) Of Engagement Activity 2020
 
Description Keynote presentation at 2019 Monogram 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Keynote, plenary lecture at Monogram 2019
Year(s) Of Engagement Activity 2019
 
Description Life Sciences Symposium 2018-02-02 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Amanda Burridge presented work by the Bristol Cereal Genomics team.
Year(s) Of Engagement Activity 2018
 
Description Meeting with South African deligation to discuss meiosis, genotyping and wheat breeding 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Meeting with British Council lead South African delegation to discuss wheat breeding and possible further links
Year(s) Of Engagement Activity 2018
 
Description Meeting with international experts in wheat breeding and recombination 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Meeting of international experts in wheat breeding and recombination/marker development to consider future prospects
Year(s) Of Engagement Activity 2018
 
Description Monogram 2018 - John Innes Centre 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Amanda Burridge presented 'Rapid and Affordable Genotyping by Sequencing Optimised for Hexaploid Wheat' at Monogram 2018
Year(s) Of Engagement Activity 2018
 
Description ONLINE workshop in meiosis 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Several meetings were carried out to engage during the lockdown with plant meiosis groups. Carried out via Zoom. With presentations and discussions.
Year(s) Of Engagement Activity 2020
 
Description Open Visit Days University of Birmingham 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Taster Lecture for Open Visit Days at University of Birmingham: "Using genetics to feed the World". Talk about our research and its impact.
Different days during 2019 and 2020 to interested future students and their families/friends accompanying them. Around 100-250 people per day.
Year(s) Of Engagement Activity 2019,2020
 
Description Outreach activity for School visit to University of Birmingham 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact Genetic research outreach. Activities to show DNA extraction, DNA gel electrophoresis, mutation concept and evolution of mutations in agricultural interest vegetables (Brassica oleracea).
Year(s) Of Engagement Activity 2021
 
Description Outreach exercise as part of Dynamic DNA at the University of Leicester called 'Gene Shuffling' 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact Our outreach work for BBSRC funded projects aims to explain the process of meiotic recombination in wheat. We presented posters and the chromosome model at Dynamic DNA at the University of Leicester 7-8th September, 2016. Over 400 local school children mixed and matched the wheat chromosome agronomical traits using the model, to see if they could generate a new super variety of wheat.
Year(s) Of Engagement Activity 2016
URL http://www2.le.ac.uk/departments/genetics/people/dr-james-higgins-2/outreach
 
Description Oxford Farming Conference talk 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Oxford Farming Conference talk
Year(s) Of Engagement Activity 2019
URL https://www.youtube.com/watch?v=mp0QJDivWgA
 
Description Participation in a Meet The Scientist event at Thinktank, Science Museum, Birmingham. 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Part of MEICOM ITN network public engagement activity co-ordinated by the Sanchez-Moran/Franklin lab demonstrating fun science activities to families visiting Thinktank Science Museum during school half-term week. The emphasis was on the importance of plant meiosis research and issues of food security and climate change. Children and parents were able to participate in activities such as extraction of DNA from strawberries, loading a DNA gel, viewing plant chromosomes down a microscope and games involving learning about DNA sequencing and crop wild relatives & plant breeding. This generated plenty of questions and discussion and even quite young children were interested and able to engage in the activities.
Year(s) Of Engagement Activity 2019
URL https://twitter.com/biobosie/status/1098529947864444929
 
Description Participation in an open day or visit at my research institution - Outreach exercise as part of Dynamic DNA at the University of Leicester called 'Gene Shuffling' 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact We explained the process of meiotic recombination so that advantageous crop traits could be brought together from different chromosomes, thus providing new, better varieties. The impact was to present the concept of 'gene shuffling', which is why people (except twins) are genetically different, so that the students could understand that human and plant meiotic recombination is very similar.
Year(s) Of Engagement Activity 2017
 
Description PhD student visit to Bristol for training/exchange 3/9/18 - 15/10/18 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact One month training exchange visit by PhD student Mohammad Shamshad to Bristol University. Visit involved practical and bioinformatic training.
Year(s) Of Engagement Activity 2018
 
Description Plant Development and Evolution International Workshop 2018-02-22 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Amanda Burridge attended the Plant Development and Evolution International Workshop in Zurich with the presentation 'Improving Wheat Photosynthesis using Wild Relatives'
Year(s) Of Engagement Activity 2018
 
Description Plant and Animal Genomes (PAG) XXVI 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Amanda Burridge attended Plant and Animal Genomes (PAG) XXVI and presented 'CerealsDB Version 4.0: A Review of Tools and Data for Wheat Breeders and Research Scientists'
Year(s) Of Engagement Activity 2018
 
Description Poster EMBO Workshop in Meiosis in La Rochelle August 2019 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact EMBO0 Workshop on Meiosis in La Rochelle Poster presentation by Postdoc Pablo Parra
Year(s) Of Engagement Activity 2019
URL https://colloque.inrae.fr/embo_conference_on_meiosis2019/
 
Description Poster Presentation at Monogram Conference 2017 Bristol 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Poster Presentation at Monogram Conference Bristol 2017. Title: "Early meiotic progression in hexaploid bread wheat". Authors: Kim Osman, Eugenio Sanchez-Moran and F. Chris H. Franklin
Year(s) Of Engagement Activity 2017
URL http://www.monogram.ac.uk/MgNW2017.php
 
Description Poster Presentation at XXVI PAG San Diego 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Poster presentation at XXVI PAG conference in San Diego 2018. Title: "Spatio-temporal asymmetry of the meiotic pathway in hexaploid bread wheat". Authors: Kim Osman, Eugenio Sanchez-Moran and F. Chris H. Franklin
Year(s) Of Engagement Activity 2018
URL http://www.intlpag.org/
 
Description Poster presentation at PAG XXV San Diego 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Poster presentation at PAG XXV conference in San Diego 2017. Title: "Topoisomerase II is required for programmed chromosome reorganization during meiosis and mitosis in plants".
Authors: Marina Martínez García, Eugenio Sanchez-Moran, Chris Franklin.
Year(s) Of Engagement Activity 2017
URL http://www.intlpag.org/
 
Description Poster presentation: Recombination progression and chromatin architecture in hexaploid bread wheat. British Meiosis Meeting, 2018. University of Sussex, Brighton. 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact British Meiosis Community annual meeting to discuss current research across a range of organisms. Emphasis is on postgraduate & postdoctoral career development & networking opportunities. A mix of talks and poster presentations with opportunities for discussion of direction of meiotic research. Includes talks from invited international speakers.
Year(s) Of Engagement Activity 2018
URL http://www.sussex.ac.uk/lifesci/nealelab/research/bmm2018
 
Description Presentation at Monogram, Nottingham University, 2019 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Kim Osman presented a poster at Monogram, the annual meeting of UK based cereal researchers which provides a link between science and commercial exploitation.The presentation provoked interest and discussion and provided an opportunity to disseminate research data which has potential implications for plant breeding
Year(s) Of Engagement Activity 2019
 
Description Presentation at the British Meiosis Meeting, University of Aberystwyth, 2019 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Kim Osman gave a talk at the BMM which is attended by members of the British and European meiosis community. The BMM gives early career researchers, including doctoral students, a chance to participate in a conference and present their research in a supportive and friendly environment. The talk generated interest and discussion and led to the exchange of useful information between different areas of meiosis research.
Year(s) Of Engagement Activity 2019
 
Description Presentation at the EMBO Workshop on Meiosis, La Rochelle, France, 2019 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Kim Osman presented a research poster at EMBO 2019. This workshop brings together highly regarded researchers from across the international meiosis community, providing an opportunity for productive discussion, feedback and research advice from experts in their fields. Presenting here generated a lot of interest and led to new contacts and potential future collaborations.
Year(s) Of Engagement Activity 2019
 
Description Presentation at the Plant and Animal Genome Conference, San Diego 2020 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact James Higgins presented this project in the IWGSC workshop, which is one of the largest gatherings of wheat geneticists. It sparked questions and discussion and potentially new collaborations.
Year(s) Of Engagement Activity 2020
URL http://www.wheatgenome.org/Meetings-and-Workshops/PAG-2020/Speaker-Profiles/James-Higgins
 
Description Presentation at the Plant and Animal Genome Conference, San Diego, 2020 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Kim Osman presented a talk in the Plant Cytogenetics workshop and a poster at PAG, a large international conference which attracts wheat researchers from all over the world. The presentations generated questions and discussion and led to new contacts and possible future collaborations.
Year(s) Of Engagement Activity 2020
 
Description Presentation by hosted visitor as part of INEW project 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact As part of training exchange, Bristol University staff and PhD students were invited to a presentation by visitor Mohammad Shamshad of the Punjab Agricultural University, Ludhiana.
Year(s) Of Engagement Activity 2018
 
Description Progress meeting at Lancaster 2017-11-22 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Amanda Burridge attended and presented data at an IWYP meeting attended by delegates from Nottingham University, Lancaster University and Essex University
Year(s) Of Engagement Activity 2017
 
Description Public dialog and debate 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact A pint of science debate on the price of bread and wheat breeding
Year(s) Of Engagement Activity 2017
 
Description Radio broadcast Farming today 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact Interview for farming today on wheat breeding and its importance; 14th July 2017
Year(s) Of Engagement Activity 2017
 
Description Rank Prize acceptance speech 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Rank prize (2018) acceptance speech
Year(s) Of Engagement Activity 2017
URL http://www.rankprize.org/index.php/prizes/prizes-2018
 
Description Rank Symposium on "The shape of wheat to come" 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Study participants or study members
Results and Impact The Rank Symposium of "The shape of wheat to come" was a four day event organised by Edwards and Higgins to promote the area of recombination to a wide range of international scientists ranging from PhD students to retired professors
Year(s) Of Engagement Activity 2018
 
Description SIGA Congress Angelo Bianchi 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Over 100 attendants and discussion of new tools for wheat genomic research.
Year(s) Of Engagement Activity 2020
 
Description Seminar at the University of Birmingham "Manipulating meiotic recombination to produce the crops of the future" 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Postgraduate students
Results and Impact On line seminar via Zoom. Exposing our research in the lab.
Year(s) Of Engagement Activity 2021
 
Description Stakeholder Workshop: Social Responsibility and Wheat Research 13/9/18 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Stakeholders talked about their own interests (and/or those of their community) in relation to the many uses of wheat. The event also considered stakeholder responses as the basis for a report on social responsibility and wheat research targeted at policy audiences
Year(s) Of Engagement Activity 2018
 
Description THINK TANK MUSEUM BIRMINGHAM - MEET THE SCIENTIST EVENT 21st February 2019 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact The event involved the preparation of different activities (7) for the day. The whole lab participated and different colleagues from different labs in Europe came to support us. The event was organised at the Think Tank Museum at Birmingham and it run during the whole day. We prepared posters, leaflets, practical activities and show different results to the general public.
Year(s) Of Engagement Activity 2019
URL http://www.birminghammuseums.org.uk/thinktank/whats-on
 
Description Talk at Plant and Animal Genome Conference, San Diego 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Presentation by Dr Stuart Desjardins at the Plant and Animal Genome conference, San Diego to disseminate results to the scientific community for discussion.
Year(s) Of Engagement Activity 2018
URL https://pag.confex.com/pag/xxvi/meetingapp.cgi/Session/4843
 
Description Talk at Wheat Genome Initiative Network meeting by Co-I Higgins 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Talk at the WIGN meeting to disseminate aims and purpose of grant to the wheat community.
Year(s) Of Engagement Activity 2016
 
Description Taste Lecture during Open Day 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Presentation of a lecture to future applicants and family/friends. Recorded on Feb 2020 and used as a video online since then. Presenting part of the reasons of our research.
Year(s) Of Engagement Activity 2020,2021
 
Description University of Birmingham Open Day 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Showcase of the Plant Research carried out by our lab. Directed to the general public to outreach and explain what we do and its importance. Open days provide an opportunity to face big numbers of the general public, from future students to any member of their families. Including a huge age range from ~5-90 years old.
Year(s) Of Engagement Activity 2018
 
Description University of Birmingham Open Day 14th October 2017 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Presentation of our Research using posters, activities and workshops showing microscopes and plants. Supported by other members of staff.
Year(s) Of Engagement Activity 2017
 
Description University of Cambridge Science festival 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Laboratory members presented work on genetics to attendees for the Science festival.
Year(s) Of Engagement Activity 2011,2012,2013,2014,2015,2016,2017,2018
 
Description Velcourt Agronomist annual conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Velcourt Agronomist annual conference
Year(s) Of Engagement Activity 2020
 
Description Visitors from the University of Florence 2-6 July 2018 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Academic visit from Alberto Masoni and Massimo Gori of the University of Florence. Visit was for training, data sharing and discussion of future collaboration opportunities
Year(s) Of Engagement Activity 2018
 
Description Wheats and Women International Conference, National Research Council, Rome, 2018-06-14 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact Amanda Burridge attended and presented at the first Women in Wheat (Carlotta Award) conference in Rome.
Year(s) Of Engagement Activity 2018
 
Description media interest (New University of Leicester study to improve crop plants) 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Raised awareness of research that is current at the University of Leicester.

Other researchers and students knew what research I was doing.
Year(s) Of Engagement Activity 2015
URL http://www2.le.ac.uk/offices/press/press-releases/2015/august/new-university-of-leicester-study-to-i...