Development of NanoKick Bioreactor

Lead Research Organisation: University of Glasgow
Department Name: College of Medical, Veterinary &Life Sci

Abstract

Bone graft is the most transplanted tissue after blood. It is in short supply and demand is increasing with the aging population. Taking graft from a patient to transplant back to the patient is possible but results in morbidity of the donor site (normally the pelvis). We have developed a novel bioreactor, called Nanokick, which can be used to efficiently and effectively convert mesenchymal stem cells (MSCs - the bones natural stem cell supply) into osteoblasts (bone building cells). It works by supplying tiny kicks to cells. Our approach will provide technology that enables provision of 3D living bone derived from a patients own cells that produces effective repair. Areas this would be useful would include all bone reconstructions, spinal fusion and joint replacement. These in no need for chemicals and associated side effects (e.g. widely used bone morphogenic protein is now associated with adverse effects). In this work we will develop our technology towards a commercial product.

Publications

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Donnelly H (2018) Current approaches for modulation of the nanoscale interface in the regulation of cell behavior. in Nanomedicine : nanotechnology, biology, and medicine

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Robertson SN (2018) Control of cell behaviour through nanovibrational stimulation: nanokicking. in Philosophical transactions. Series A, Mathematical, physical, and engineering sciences

 
Description We have developed a bioreactor that can be used to engineer 3D bone that could be used for drug testing instead of animals. The bioreactor could also be used to produce e.g. tissue engineered bone graft.
Exploitation Route We are moving towards spin-out formation
Sectors Healthcare,Pharmaceuticals and Medical Biotechnology

 
Description The results are being used in outreach e.g. Royal Society Summer Exhibition 2018. Also, we are building an impact case around our bone technologies of which nanokicking is one. Cell produced by the bioreactor will be used in a human trial in 2021 for bone repair.
Sector Healthcare
Impact Types Societal

 
Description training of practioners and researchers
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
 
Description BCRT grant awarded to Dr P.M. Tsimbouri
Amount £30,000 (GBP)
Organisation Bone Cancer Research Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 02/2015 
End 07/2015
 
Description Early diagnosis and intervention of osteoporosis using nanovibrational stimulation
Amount £480,000 (GBP)
Funding ID ST/S000852/1 
Organisation Science and Technologies Facilities Council (STFC) 
Sector Academic/University
Country United Kingdom
Start 11/2018 
End 10/2020
 
Description Engineering growth factor microenvironments - a new therapeutic paradigm for regenerative medicine
Amount £3,661,144 (GBP)
Funding ID EP/P001114/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Academic/University
Country United Kingdom
Start 10/2016 
End 09/2021
 
Description Impact Acceleration Account (IAA)- Consultant to advise on pharmaceutical industry market for Nanokick technology
Amount £20,000 (GBP)
Organisation Science and Technologies Facilities Council (STFC) 
Sector Academic/University
Country United Kingdom
Start 01/2017 
End 02/2017
 
Description Impact Acceleration Account (IAA)- Nanokicking: Expanding the proposition for the Pharma industry
Amount £10,000 (GBP)
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 01/2018 
End 12/2018
 
Description Wellcome Trust ISSF Early Career Researcher Fund
Amount £18,350 (GBP)
Organisation Wellcome Trust 
Department Wellcome Trust Institutional Strategic Support Fund
Sector Charity/Non Profit
Country United Kingdom
Start 03/2018 
End 12/2018
 
Title Use of NanoKick Bioreactor for chondrogenic differentiation of MSCs 
Description Modification of cell culture method to induce chondrogenic differentiation of MSCs when using the NanoKick Bioreactor. 
Type Of Material Model of mechanisms or symptoms - in vitro 
Year Produced 2017 
Provided To Others? No  
Impact Preliminary data obtained further funding from a Wellcome Trust ISSF Early Career Catalyst Fund (~£18300). 
 
Title Control of cell behaviour through nanovibrational stimulation: nanokicking 
Description  
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? Yes  
 
Description Collaboration for Synthesis of Osteogenic Metabolites and Chemical Derivatives 
Organisation University of Glasgow
Department School of Chemistry
Country United Kingdom 
Sector Academic/University 
PI Contribution Identification of interesting metabolites in osteogenesis and in vitro testing of osteogenic potential
Collaborator Contribution Chemical synthesis of metabolite molecules
Impact We will shortly publish results from this collaboration.
Start Year 2017
 
Description Collaboration with Anacail (Spin off) 
Organisation Anacail Ltd
PI Contribution We have stabilized a collaboration with Anacail to sterilize protein coating preserving the bioactivity. This will allow the commercialization of future implants in sterilize conditions.
Collaborator Contribution The have been performing the sterilization of the samples and given ideas.
Impact We have been able to find a range of doses to preserve the bioactivity of the big protein coatings and sterilize the samples at the same time. In the future we are going to be working towards finding the right amount of doses to preserve the bioactivity of smaller molecules (such as growth factors).
Start Year 2017
 
Description Collaboration with Dr Lee Buttery, University of Nottingham 
Organisation University of Nottingham
Country United Kingdom 
Sector Academic/University 
PI Contribution Provision of a Nanokick bioreactor
Collaborator Contribution Testing of the device and expertise in chemotaxis/osteogenic culture.
Impact Disciplines: Physics, cell engineering
Start Year 2017
 
Description Collaboration with Dr Paul Brennan, University of Edinburgh 
Organisation University of Edinburgh
Country United Kingdom 
Sector Academic/University 
PI Contribution Provision of a Nanokick bioreactor
Collaborator Contribution Device testing and expertise in glialblastoma stem cells.
Impact Disciplines: Neuro oncology, cell engineering
Start Year 2018
 
Description Collaboration with Dr. Manus Biggs in National University of Ireland, Galway to creat Dual Piezoelectric/Nanovibration system for rapid bone regeneration 
Organisation National University of Ireland, Galway
Country Ireland 
Sector Academic/University 
PI Contribution Combining piezoelectric scaffold provided by Dr Manus group with our nanovibrator for MSCs osteogenic stimulation.
Collaborator Contribution Synthesizing piezoelectric scaffold.
Impact The collaboration just started recently. We will publish a paper in near future.
Start Year 2017
 
Description Collaboration with Geistlich 
Organisation Geistlich
Country Switzerland 
Sector Private 
PI Contribution Testing of in vitro cell culture on Geistlich implant materials
Collaborator Contribution Contribution of implant materials from Geistlich
Impact Disciplines involved - Dentistry, cell engineering, materials
Start Year 2018
 
Description Collaboration with Prof Bo Su, University of Bristol 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Provision of a Nanokick bioreactor
Collaborator Contribution Testing of the device and expertise in bacterial culture.
Impact Disciplines: Cell engineering, biomaterials
Start Year 2018
 
Description Collaboration with Prof Godfrey Smith, University of Glasgow 
Organisation University of Glasgow
Country United Kingdom 
Sector Academic/University 
PI Contribution Provision of a Nanokick bioreactor
Collaborator Contribution Testing of the device and experience with cardiomyocyte culture.
Impact Disciplines: cell engineering, cardio physiology, physics.
Start Year 2018
 
Description Collaboration with Prof Stuart Reid, University of Strathclyde 
Organisation University of Strathclyde
Country United Kingdom 
Sector Academic/University 
PI Contribution Together, we have designed a new bioreactor and consumables for it.
Collaborator Contribution They design and build the bioreactors.
Impact THis is a long standing collaboration in which we designed and build the nanovibrational bioreactor (originally Nanoforce, now Nanokick). We have worked togther, produced patents and publications as well as securing further funding.
Start Year 2011
 
Description Collaboration with the Scottish National Blood Transfusion Service 
Organisation NHS National Services Scotland (NSS)
Department Scottish National Blood Transfusion Service
Country United Kingdom 
Sector Public 
PI Contribution Provision of technology for osteogenic cell culture.
Collaborator Contribution Expertise in GMP manufacture of cellular therapies.
Impact Disciplines: GMP manufacture, cell engineering, physics
Start Year 2016
 
Description Souhtampton Collaboration 
Organisation University of Southampton
Department Bone and Joint Research Group
Country United Kingdom 
Sector Academic/University 
PI Contribution This is a long term collaboration where cells, materials and expertise are shared to drive research
Collaborator Contribution This is a long term collaboration where cells, materials and expertise are shared to drive research
Impact A large number of papers, grants and IP.
 
Title Mechanical Bioreactor 
Description Design of a novel nanovibrational bioreactor for bone graft production 
IP Reference WO2017029393A1 
Protection Patent application published
Year Protection Granted 2017
Licensed No
Impact None yet
 
Description FEBS Workshop Biological Surfaces and Interfaces: Interface Dynamics, 2nd-7th July 2017, Sant Feliu de Guixols, Catalonia, Spain 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Mr W. Orapiriyakul had a Poster presentation at FEBS Workshop Biological Surfaces and Interfaces: Interface Dynamics, 2nd-7th July 2017, Sant Feliu de Guixols, Catalonia, Spain
Year(s) Of Engagement Activity 2017
 
Description Glasgow Orthopaedic Research Initiative (GLORI 2018), 23d February 2018, Glasgow, UK. 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Mr W. Orapiriyakul had a Poster presentation at Glasgow Orthopaedic Research Initiative (GLORI 2018), 23th Febuary 2018, Glasgow, UK.
Year(s) Of Engagement Activity 2018
 
Description 28th Annual Conference of the European Society for Biomaterials (ESB) 4-8th September 2017, Athens, Greece. 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Mr W. Orapiriyakul: Oral presentation at 28th Annual Conference of the European Society for Biomaterials (ESB) 4-8th September 2017, Athens, Greece.
Year(s) Of Engagement Activity 2017
 
Description 29th European Conference on Biomaterials (ESB 2018), 9-13th September 2018, Maastricht, Netherlands. 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Mr W. Orapiriyakul had a Poster presentation in 29th European Conference on Biomaterials (ESB 2018), 9-13th September 2018, Maastricht, Netherlands.
Year(s) Of Engagement Activity 2018
 
Description 5th TERMIS World Congress 2018, 4-7th September 2018, Kyoto, Japan. 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact mr W.Orapiriyakul had a Poster presentation in 5th TERMIS World Congress 2018, 4-7th September 2018, Kyoto, Japan.
Year(s) Of Engagement Activity 2018
 
Description BCRT annual conference July 2017 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Dr Tsimbouri was asked to have a public exhibition at the BCRT annual conference in Birmingam international in July 2017,about the Nanokicking Bioreactor and its potential uses in bone regeneration.
Year(s) Of Engagement Activity 2017
URL https://www.bcrt.org.uk/get-involved/events-and-challenges/bone-cancer-conference-2017
 
Description BLOG CeMi: NANOKICKING STEM CELLS TO GROW NEW BONE 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Dr Monica P. Tsimbouri wrote a blog about the people, work and challenges involved for the recent paper
Tsimbouri, Childs et al. Stimulation of 3D osteogenesis by mesenchymal stem cells using a nanovibrational bioreactor. Nat. Biomed. Eng. http://doi.org/10.1038/s41551-017-0127-4 (2017).
Year(s) Of Engagement Activity 2017
URL https://www.gla.ac.uk/research/az/thecemi/blog/nanokickingstemcellstogrownewbone/
 
Description BORS 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact We organised the British Orthopedic Society annual conference in Glasgow. The conference sparked discussion after every talk and new collaborations were initiated between research and clinical groups.
Year(s) Of Engagement Activity 2016
 
Description Biomaterials seminar 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact Mr W Orapiriyakul gave a talk at the Biomaterials seminars session on 13/11/18
Year(s) Of Engagement Activity 2018
 
Description Biomaterials seminar 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact Wich Orapiriyakul, Oral presentation, Biomaterial seminar, University of Glasgow, 1st Nov, 2016
Year(s) Of Engagement Activity 2016
 
Description Conference - Oral Presentation - BORS 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact 2016 BORS conference was organized in Glasgow, were I gave a talk with the title 'Engineering osteogenic coatings' and new collaborations were initiated between research and clinical groups afterwards.
Year(s) Of Engagement Activity 2016
 
Description Conference Talk, GLORI 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact GLORI conference meeting, presenting research outcome on bone tissue regeneration with questions and discussion afterwards.
Year(s) Of Engagement Activity 2016
 
Description Conference presentation 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Wich Orapiriyakul Poster presentation, British Orthopaedic research Society (BORS), UK, 5-6th September 2016, Glasgow, UK
Year(s) Of Engagement Activity 2016
URL https://www.uofgcce.org/bors-2016
 
Description Conference presentation 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Wich Orapiriyakul Poster presentation in 10th UK Mesenchymal Stem Cell Meeting, 5th December 2016 York, UK.
Year(s) Of Engagement Activity 2017
 
Description Conference presentation 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Wich Orapiriyakul Poster presentation at FEBS Workshop Biological Surfaces and Interfaces: Interface Dynamics, 2nd-7th July 2017, Sant Feliu de Guixols, Catalonia, Spain
Year(s) Of Engagement Activity 2017
URL https://mimeresearch.com/biointerfaces2017/
 
Description GLORI at the CeMi 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Mr Ian Kennedy presented a talk on
"Nanoscale vibrations to modulate osteogenesis"
Glasgow Orthopedic Research Initiative 2018
23rd November 2018
Year(s) Of Engagement Activity 2018
 
Description GLORI at the CeMi 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Tom Hodgkinson, Talk
"Identification and in vitro screening of osteogenic metabolites through supplement-free
nanovibration-driven mesenchymal stem cell differentiation"
Glasgow Orthopedic Research Initiative 2018
23rd November 2018
Year(s) Of Engagement Activity 2018
 
Description GLORI conference organisation 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Planning and Organisation of Dr Monica P Tsimbouri the scientific mentor of the Glasgow Orthopaedic Research Initiative (GLORI). GLORI has been established to encourage collaboration between the basic sciences, applied sciences, engineering and clinic. This has the aim of bringing the latest ideas in basic materials research into use to deliver the next-generation of orthopaedic care. It combines expertise from orthopaedic surgeons, biologists, engineers and chemists not only from Glasgow and Strathclyde Universities but the rest of Scotland too and also with the view to expand to the rest of the UK.
Year(s) Of Engagement Activity 2018
 
Description Glori2018 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Submitted a research abstract, stimulating discussion and chaired a conference session on bone regeneration strategies
Year(s) Of Engagement Activity 2018
 
Description IKEA at home with life sciences 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Dr Monica P. Tsimbouri
participated at the
IKEA at Home with Life Sciences
A team of students, researchers and support staff represented the Institute at IKEA on Saturday 24th November 2018 as part of the MVLS at IKEA event.
Year(s) Of Engagement Activity 2018
URL https://www.gla.ac.uk/researchinstitutes/biology/newsevents/headline_581051_en.html?utm_medium=email...
 
Description International Conference presentation 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Wich Orapiriyakul did a Podium presentation at 28th Annual Conference of the European Society for Biomaterials (ESB) 4-8th September 2017, Athens, Greece
Year(s) Of Engagement Activity 2017
URL http://ESB2017.org
 
Description Invited talk at BCRT Scotland day May 2017 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact This was an invited talk for Dr Monica P. Tsimbouri by BCRT in Perth May 16th 2017. The presentation was intended for clinical partitioners as well as patients and carers affected by bone cancers. There was a lot of interest and discussions after the talk and Dr Tsimbouri was asked to give a further presenation in the future.
Year(s) Of Engagement Activity 2017
URL https://www.bcrt.org.uk/news/2017/may/our-first-scottish-patient-and-carer-day
 
Description Local Talk 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact Wich Orapiriyakul Oral presentation, GLORI 2016, University of Glasgow, 15th Dec 2016
Year(s) Of Engagement Activity 2016
 
Description Media presentation 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Radio interview for the Today Programme, Radio Scotland and BBC World Service
Year(s) Of Engagement Activity 2016
 
Description NEB community: the story behind the paper 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Dr P.M. Tsimbouri and Dr P. Childs were asked by the NEB community to write a story behind their recent paper
Tsimbouri, Childs et al. Stimulation of 3D osteogenesis by mesenchymal stem cells using a nanovibrational bioreactor. Nat. Biomed. Eng. http://doi.org/10.1038/s41551-017-0127-4 (2017).

Story title:
Growing bone using nanovibration:
A reproducible method for mechanically driving stem-cell osteogenesis in 3D culture.
Year(s) Of Engagement Activity 2017
URL http://go.nature.com/2xVgSNN
 
Description Nanotoxicology Meeting 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact Invited talk for the Naotoxicology Society
Year(s) Of Engagement Activity 2016
 
Description Oral Presentation at Biomaterials Seminar, University of Glasgow 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact Presented research on nano vibrational differentiation of mesenchymal stem cells as part of the biomaterials seminar series at the University of Glasgow
Year(s) Of Engagement Activity 2018
 
Description Press release to announce Find a Better Way funding 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Press release to announce the award of our Find a Better Way Project
Year(s) Of Engagement Activity 2016
 
Description Programme grant announcement 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Press release to announce Glasgow EPSRC Programme grant
Year(s) Of Engagement Activity 2016
 
Description Public outreach-Royal Society of London Summer Exhibition 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Nanokicking" Royal Society Science summer exhibition in London 2016.
We promoted our Nanokicing research to the public and explaining the potential of nanokicking in
bone regeneration and also its use as a tool in cancer research.
Year(s) Of Engagement Activity 2016
 
Description Royal Society Summer Exhibition Press Release 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Press release from the Royal Society about our nanokick exhibit
Year(s) Of Engagement Activity 2016
 
Description Royal Society of Chemistry Biomaterials Meeting 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact Conference presentation
Year(s) Of Engagement Activity 2017
 
Description SSN invited talk 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Dr P. M. Tsimbouri was invited to present the use of nanotopography on Titanium orthopedic implants and the use of Nanokicking Bioreactor for bone regeneration and also as a tool for the descovery of metabolic targets in bone cancer for pharma.
Year(s) Of Engagement Activity 2016
 
Description Scottish Metabolomics Network 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Postgraduate students
Results and Impact Invited talk
Year(s) Of Engagement Activity 2016
 
Description Talk at GLORI2018 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Dr Monica P Tsimbouri delivered a talk on behalf of Prof Dalby at GLORI2018
Year(s) Of Engagement Activity 2018
 
Description The University Network ((TUN) 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Dr Monica P. Tsimbouri was invited by the The University Network ((TUN), a global media company for college students available in 108 languages) to write an article about the nanokicking project. (https://www.tun.com/blog/nanokicking-technology-bone-growth-development/)
Year(s) Of Engagement Activity 2017
URL https://www.tun.com/blog/nanokicking-technology-bone-growth-development
 
Description school workshop: Bones and bone cells, 2017 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Dr P.M. Tsimbouri has organised a full day workshop for P5,P6 and P7 school pupils at the Milngavie primary school.
The workshop involves presentation slides and Q/A session with the children about the skeleton, bones and bone cells. This followed by hands on experience looking at fixed cells using bright field microscopes. The children were given colour-in pages and also word searches to take home.
Year(s) Of Engagement Activity 2015,2017