US Partnering Award: Vector-borne diseases in the UK & US: common threats and shared solutions

Lead Research Organisation: University of Liverpool
Department Name: Institute of Infection and Global Health

Abstract

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Publications

10 25 50
 
Description Activity.In October 2017 we held a 3 day workshop at University of California Davis, organised by myself and Dr Janet Foley at UCD. The themes were: 1. Climate as a driver of vector-borne disease emergence ; 2.Vector-borne diseases of plants; 3. UK/US Europe VBDs: common threats and shared solutions. Delegates from the UK came from University of Liverpool, Pirbright Institute, John Innes Centre and Museum of Wales. Delegates from the US came from UCD, UC Riverside, UC Berkeley, University of Wisconsin Madison, and State wildlife and agriculture departments. The total number of attendees was 28.

In 2018 we funded four cross-Atlantic research placements for PhD students to undertake some research in a partner's lab. Three students came to the UK (2 to Liverpool, 1 to Pirbright) and one travelled from Liverpool to UC Riverside. Through these placements we hope that joint publications will result and stronger collaborations will follow.
Exploitation Route Ultimately we want to develop active research collaborations between UK and US researchers in the area of VBDs
Sectors Agriculture, Food and Drink,Environment,Healthcare

 
Description Center for Health in the Human Ecosystem , University of Idaho 
Organisation University of Idaho
Country United States 
Sector Academic/University 
PI Contribution I will be contributing to the new, annual, course, Biology of Vector-borne diseases. June 24-29 June. The course's mission is to "Create a knowledge network for a diverse community of practitioners that persists, grows, and transforms science and interventions for plant, animal, and human vector-borne diseases". Some of my presentation will concern BBSRC-funded research.
Collaborator Contribution The partners have developed the course, and invited a select group of expects to present.
Impact none yet
Start Year 2018
 
Description Collaboration with Public Health England 
Organisation Public Health England
Country United Kingdom 
Sector Public 
PI Contribution Collaborating on mosquito infection work, in part through Health Protection Research Unit in Emerging and Zoonotic Infection (joint venture of University of Liverpool, Liverpool School of Tropical Medicine, and Public Health England)
Collaborator Contribution Intellectual - ideas, suggestions for research activity
Impact Through the HPRU our work is passed rapidly to the HAIRS committee
Start Year 2015
 
Description Pirbright Laboratory 
Organisation The Pirbright Institute
Country United Kingdom 
Sector Academic/University 
PI Contribution Partners in this project
Collaborator Contribution Partners in this project
Impact n/a
Start Year 2016
 
Description UK-US partnership (VBD) 
Organisation Public Health England
Country United Kingdom 
Sector Public 
PI Contribution Newly awarded BBSRC UK-US partnership award; to hold 4 workshops over 4 years. I am PI and will lead the project
Collaborator Contribution Providing expertise in specific areas of vector-borne disease
Impact none yet
Start Year 2016
 
Description UK-US partnership (VBD) 
Organisation The Pirbright Institute
Department Avian viral Diseases
Country United Kingdom 
Sector Private 
PI Contribution Newly awarded BBSRC UK-US partnership award; to hold 4 workshops over 4 years. I am PI and will lead the project
Collaborator Contribution Providing expertise in specific areas of vector-borne disease
Impact none yet
Start Year 2016
 
Description UK-US partnership (VBD) 
Organisation University of California, Davis
Country United States 
Sector Academic/University 
PI Contribution Newly awarded BBSRC UK-US partnership award; to hold 4 workshops over 4 years. I am PI and will lead the project
Collaborator Contribution Providing expertise in specific areas of vector-borne disease
Impact none yet
Start Year 2016
 
Description UK-US partnership (VBD) 
Organisation University of California, Riverside
Country United States 
Sector Academic/University 
PI Contribution Newly awarded BBSRC UK-US partnership award; to hold 4 workshops over 4 years. I am PI and will lead the project
Collaborator Contribution Providing expertise in specific areas of vector-borne disease
Impact none yet
Start Year 2016
 
Description University of California Davis 
Organisation University of California, Davis
Department Centre for Vectorborne Disease
Country United States 
Sector Academic/University 
PI Contribution Partners in previous UK-US partnership award (Japanese encephalitis in Himalayas)
Collaborator Contribution Visits to Nepal and UK. Co-authorship of publication
Impact Joint Publication in Transactions of Hygiene and Tropical Medicine
Start Year 2013
 
Description University of California Riverside 
Organisation University of California, Riverside
Country United States 
Sector Academic/University 
PI Contribution Partners in project
Collaborator Contribution Partners in project
Impact n/a
Start Year 2016
 
Description Vector Biology course, University of Idaho, USA 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Baylis attended and delivered teaching at the inaugural 1 week training course developed by one of the partners in this network project.
Year(s) Of Engagement Activity 2018
URL https://www.uidaho.edu/cals/center-for-health-in-the-human-ecosystem/education/vector-borne-diseases
 
Description Vector-borne diseases in the UK & US: common threats and shared solutions - a workshop hosted by UC Davis 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Study participants or study members
Results and Impact A 3 day workshop was held at UC Davis, involving all partners in this project, and a number of other people involved in VBD research in California, including those employed by the State to undertake surveillance and control.

Key themes covered were;
Session 1: Climate as a driver of vector-borne disease emergence
Talk 1. Cyril Caminade. Climate change and vector-borne diseases, an update from the trenches
Talk 2. Chris Barker. Use of climate data and surveillance to predict risk for West Nile virus disease
Talk 3. Marcus Blagrove. Vector competence of temperate mosquitoes for arboviruses

Session 2: Climate as a driver of vector-borne disease emergence
Talk 4. Matthew Baylis. Modelling the future impact of bluetongue in the UK
Talk 5. Janet Foley. Impacts of climate on expanding tick distributions
Talk 6. Marie McIntyre. The big deal with big data - large scale assessment of the sensitivity of pathogens to climate
Talk 7. Christine Johnson- Vector-borne virus transmission at the wildlife-human interface

Breakout: assigned goal - summarize what seems to be know about climate and what the next needs and opportunities are (45 minutes)
a. Plant vectors
b. Mosquito
c. Ticks

Tour of facility

FIELD TRIP

Overview of the new Center of Excellence: Chris Barker (30 minutes)

Session 3: Vector-borne diseases of plants
Talk 8. Michael Wilson. Xylella has arrived in Europe!: effects, reactions and research
Talk 9. Diane Ullman. Understanding How Thrips Vectors and Viruses They Transmit May Interact to Manipulate Plant Hosts
Talk 10. Clare Casteel. Aphid-transmitted viruses
Talk 11. Bob Gilbertson. The need and opportunity for new approaches for management of insect-transmitted viruses of plants in California
Talk 12. Russell Groves & Justin Clements. The diversity of leafhopper-transmitted aster yellows phytoplasmas in (carrot) crop fields in Wisconsin and southern USA. [25 minutes]
Talk 13. Saskia Hogenhout. How phytoplasma virulence proteins contribute to leafhopper dispersal and transmission
Talk 14. Neil McRoberts. Modeling citrus disease

Session 4: UK/US Europe VBDs: common threats and shared solutions
Talk 15 Simon Carpenter - Current status of arbovirus research at Pirbright and collaboration opportunities
Talk 16 Antony Wilson. Reproducibility and relevance in vector infection studies
Talk 17 Vicky Kramer. Vector-borne disease activity in California: An overview
Talk 18. Lara Harrup. Tools and Resources for Arbovirus Epidemiology in the Genomic Era

Breakout: assigned goal - rank threats and needs for threat assessment and mitigation (e.g. more money, better models, more basic science info) (45 minutes)
a. Data and bioinformatics group
b. Ecology group: led by CDPH
c. Molecular technologies group

Attendees and affiliations are:
Professor Matthew Baylis, University of Liverpool
Dr Marcus Blagrove, University of Liverpool
Dr Cyril Caminade, University of Liverpool
Dr Marie McIntyre, University of Liverpool
Dr Simon Carpenter, The Pirbright Institute
Dr Anthony Wilson, The Pirbright Institute
Dr Lara Harrup, The Pirbright Institute
Dr Michael Wilson, National Museum of Wales
Professor Saskia Hogenhout, John Innnes Centre
Dr Russell Groves, University of Wisconsin-Madison
Dr Justin Clements, University of Wisconsin-Madison
Dr Janet Foley, University of California-Davis
Dr Chris Barker, University of California-Davis
Dr. Robert Gilbertson, University of California-Davis
Dr. Christine Kreuder-Johnson, University of California-Davis
Dr. Neil McRoberts, University of California-Davis
Dr. Bill Reisen, University of California-Davis
Dr. Brad Main, University of California-Davis
Dr. Marco Marcantonio, University of California-Davis
Dr. Jay Nicholson, University of California-Davis
Dr. Emily Pascoe, University of California-Davis
Dr Alec Gerry, University of California-Riverside
Dr. Robert Lane, University of California - Berkeley
Professor Diane Ullman, University of California - Davis
Dr. Clare Casteel, University of California - Davis
Dr. Melissa Yoshimizu, CDPH
Dr. Kerry Padgett, CDPH
Dr. Anne Kjemtrup, CDPH
Dr. Vicki Kramer, CDPH
Year(s) Of Engagement Activity 2017
 
Description Vector-borne diseases in the UK workshop, 2016 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Biannual "Vector-borne diseases in the UK" workshop, Liverpool December 2016. Attended by 4 colleagues from the USA, as part of this project.
Year(s) Of Engagement Activity 2016