ConBioChem: Continuous bio-production of commodity chemicals
Lead Research Organisation:
University of Cambridge
Department Name: Biochemistry
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Planned Impact
As described in proposal submitted to IUK
Organisations
| Description | NB No funding was attached to this award, it is a placeholder for the transfer of the award to Imperial College, which never happened - in part, because of the pandemic. This is copied from the actual award (BB/N02348X/1): We have developed a computer modelling system (Flexible Nets) that allows us to represent both the metabolism of a microbe or mammalian cell together with relevant characteristics of the fermentation system in which the cells/microbes are grown. This allows us to determine the optimum conditions for the production of an industrial product by the microbe. Optimisation for different kinds of productivity may be carried out, e.g. amount of product produced by a given volume of fermenter per hour; amount of product produced per amount of biomass per hour; amount of product produced per mass of carbon source per hour. The optimised parameters can be exploited by genetic engineers in organism design or by chemical engineers in process design. |
| Exploitation Route | NB No funding was attached to this award, it is a placeholder for the transfer of the award to Imperial College, which never happened - in part, because of the pandemic. This is copied from the actual award (BB/N02348X/1): The outcomes, in terms of both the tools and controllers developed, may be used by our industrial collaborators to design, optimise, and control biotechnological processes for chemicals production. They may also be exploited by producers of biologics (e.g. antibodies) and we have been in close contact with such manufacturers to promote this. |
| Sectors | Chemicals,Healthcare,Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology |
| Description | NB No funding was attached to this award, it is a placeholder for the transfer of the award to Imperial College, which never happened - in part, because of the pandemic. This is copied from the actual award (BB/N02348X/1): In addition to the exploitation in the biotechnological production of chemicals (see below). our Flexible Nets system may be used to control industrial biotechnological processes to achieve optimal production, indicating remedial action to be taken, in real time, when malfunctions occur. |
| First Year Of Impact | 2019 |
| Sector | Chemicals,Manufacturing, including Industrial Biotechology |