A Freedom to Operate Proposal to Research Targeted Drug Delivery to the Cornea of the Eye Via Thin-Film Slow Release Technology.

Lead Research Organisation: Cardiff University
Department Name: Optometry and Vision Sciences


Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.


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Bains KK (2019) Recovering vision in corneal epithelial stem cell deficient eyes. in Contact lens & anterior eye : the journal of the British Contact Lens Association

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Chan W (2016) Topical delivery of a Rho-kinase inhibitor to the cornea via mucoadhesive film. in European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Description That we have freedom to operate in our quest to discover new ocular drug delivery modalities
Exploitation Route Research in a similar field
Sectors Healthcare,Pharmaceuticals and Medical Biotechnology

Description Follow on Fund
Amount £144,900 (GBP)
Funding ID BB/N022106/1 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 05/2017 
End 04/2018
Description Thea collaboration 
Organisation Thea Pharmaceuticals Ltd
PI Contribution Developing new drug delivery technology with commercial medical partner of contact lens drug delivery research
Collaborator Contribution Expertise in contact lens manufacture and sales
Impact NDA signed for new grant application
Start Year 2017
Title Japanese Patent Application No 2014-529066 Non-Evasive Therapy for Corneal Endothelial Dysfunction 
Description The development of a cryoprobe for transcorneal freezing including study of corneal structure-function relationships and freeze-injury changes based on our knowledge of corneal biology. Japanese Patent Application granted under the Patent No 6104249 on 10 March 2017. Prof Andrew Quantock, inventor 
IP Reference WO2013034907 
Protection Patent granted
Year Protection Granted 2017
Licensed No
Impact Pending