[Australia] Construction of Synthetic Yeast Chromosomes using BioFoundries in United Kingdom and Australia
Lead Research Organisation:
Imperial College London
Department Name: Bioengineering
Abstract
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People |
ORCID iD |
| Thomas Ellis (Principal Investigator) | |
| Paul Freemont (Co-Investigator) |
| Description | A visit by the Australian team went ahead in Q3 2019 and led to the design of 2 innovative projects that could be used as test-beds for remote collaboration between groups in Australia and the UK - one on engineering yeast and one on synchronizing automation facilities to run standardised tasks in tandem across the world. Due to the COVID-19 impact we were not able to travel and so requested that our travel money be redirected to allow these 2 innovative projects to go ahead, to demonstrate how effective UK-Australia collaboration can be achieved via remote synchronisation of research. Our request was denied. We therefore were unable to do anything until Q4 2022 when travel could go ahead. This allowed for a short meeting of Biofoundry teams in Canada. A further meeting of the synthetic yeast teams happened in Singapore in Q2 2023, at the Metabolic Engineering conference, where the research was presented to a broad industrial audience. The UK-Australian synthetic genome work was also presented at the the top international synthetic biology conference - SEED - in Los Angeles 2023. |
| Exploitation Route | As preparation for coordinated grant submissions for further international collaboration. In help in developing standards between Biofoundries in different countries. |
| Sectors | Manufacturing including Industrial Biotechology Pharmaceuticals and Medical Biotechnology |
| Description | Based on expertise in synthetic biology in yeast, synthetic genomes and biofoundry automation, two start-up companies have launched from our Australian partners. |
| First Year Of Impact | 2021 |
| Sector | Agriculture, Food and Drink |
| Impact Types | Economic |