Evaluation of market opportunities for a 'gastruloid' approach to three dimensional embryonic stem cell differentiation.
Lead Research Organisation:
University of Cambridge
Department Name: Genetics
Abstract
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People |
ORCID iD |
| Alfonso Martinez Arias (Principal Investigator) |
| Description | The award evaluted the market potential of the gastruloid system and identified value in drug discovery, in particular teratology and toxicology, as well as in disease modelling. |
| Exploitation Route | The report of teh study was used in an application of a BBSRC FOF application currently under consideration. |
| Sectors | Chemicals Healthcare |
| Description | Stem Cell Technoogies obtained a license to use our human gastruloid system to develop media to grow them efficiently (HUMAN POLARISED THREE-DIMENSIONAL CELLULAR AGGREGATES PCT/GB2019/052670) |
| First Year Of Impact | 2021 |
| Sector | Pharmaceuticals and Medical Biotechnology |
| Impact Types | Economic |
| Description | Spatial transcriptomics of human gastruloids |
| Organisation | Royal Netherlands Academy of Arts and Sciences |
| Department | Hubrecht Institute |
| Country | Netherlands |
| Sector | Academic/University |
| PI Contribution | We have provided our human gastruloids |
| Collaborator Contribution | The laboratory of Alexander van Oudenaarden at the Hubrecht Institute, has developed a technique to determine the spatial distribution of the whole genome activity in complex biological samples and have applied it to our gastruloid system. |
| Impact | A manuscript is currently under review: Moris, N., Anlas, K., van den Brink, S., Alemany, A., Schroeder, J., Gimire, S., Balayo, T., Oudenaarden, A. and Martinez Arias, A. (2020) An embryonic stem cell-based model for early human development. |
| Start Year | 2018 |
| Description | grant application |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Following the study, Wwe ineracted with a few small businesss to asses the value of our technology |
| Year(s) Of Engagement Activity | 2020 |