China Partnering Award: Does chloroplast reactive oxygen underpin plant disease resistance?

Lead Research Organisation: University of Warwick
Department Name: School of Life Sciences

Abstract

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Publications

10 25 50
 
Description We have initiated this work with a Chinese lab who are experts in reactive oxygen generation and signalling in the chloroplast. The access to their mutants and expertise has allowed us to already begin to formulate new hypotheses.
This has led to the acceptance of writing a joint review for the prestigious Annual Review of Plant Pathology.
Exploitation Route Too early
Sectors Agriculture, Food and Drink,Environment

 
Description Anatomy and functions of LTP interactomes and their relationship to small RNA signals in systemic acquired resistance
Amount £650,866 (GBP)
Funding ID BB/X013049/1 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 08/2023 
End 10/2027
 
Description Cross talk between CNLs and TNLs in effector triggered immunity 
Organisation Instituto de Hortofruticultura Subtropical y Mediterránea "La Mayora"
Country Spain 
Sector Public 
PI Contribution We established the novel techniques to monitor activated R protein signalling and looked at CNL and TNL signalling and the contribution of helper (RNLs) in the process. We then approached our Malaga partners who focus on Zar1, an "orphan" CNL to look at combinatorial challenges.
Collaborator Contribution Malaga have generated specific constructs to look at how effectors that activate plant disease resistance signalling cross talk to later chlorophyll dynamics - which is a surrogate readout for activation of, or suppression of plant disease signalling networks. Their contribution has been invaluable in enabling us to decipher activation dynamics and implicated competition for specific components in signal activation.
Impact Paper in preparation Small workshop organised for April 2023.
Start Year 2020
 
Description Cross talk between CNLs and TNLs in effector triggered immunity 
Organisation University of Malaga
Country Spain 
Sector Academic/University 
PI Contribution We established the novel techniques to monitor activated R protein signalling and looked at CNL and TNL signalling and the contribution of helper (RNLs) in the process. We then approached our Malaga partners who focus on Zar1, an "orphan" CNL to look at combinatorial challenges.
Collaborator Contribution Malaga have generated specific constructs to look at how effectors that activate plant disease resistance signalling cross talk to later chlorophyll dynamics - which is a surrogate readout for activation of, or suppression of plant disease signalling networks. Their contribution has been invaluable in enabling us to decipher activation dynamics and implicated competition for specific components in signal activation.
Impact Paper in preparation Small workshop organised for April 2023.
Start Year 2020
 
Description Keynote speaker at MPMI meeting, Glasgow 2019 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Keynote presentation on the role of the chloroplast in local and systemic signalling and presented unpublished data on the role of endoplasmic reticulum remodelling in plant pathogen interactions.
Year(s) Of Engagement Activity 2019
URL https://ismpmi.confex.com/ismpmi/2019/meetingapp.cgi/Person/4891
 
Description Presentation at the Shanghai Centre for Plant Stress Biology 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact Presented the concept of chloroplast immunity in both PAMP triggered immunity, effector triggered immunity and as a driver in generating a systemic immune signal to establish systemic acquired resistance.
Year(s) Of Engagement Activity 2019