Japan Partnering Award to Promote Synergies in Chromatin Research
Lead Research Organisation:
University of Leicester
Department Name: Molecular and Cell Biology
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
| Description | Directed evolution of a highly specific binder to determine the role of histone H3 lysine 14 ubiquitination in genomes and organisms |
| Amount | £100,000 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 07/2022 |
| End | 03/2023 |
| Description | Colaboration with Hiroshi Kimura and Hitoshi Kurumizaka |
| Organisation | Tokyo Institute of Technology |
| Country | Japan |
| Sector | Academic/University |
| PI Contribution | We are running the Japan-UK Regulation through Chromatin Conference in Leicester as the main organizers. |
| Collaborator Contribution | Our Japanese organizing partner is Hitoshi Kurumizaka from the University of Tokyo, who contributes time to organize the Japanese delegation. Hiroshi Kimura from the Tokyo Institute of Technology has provided his own grant money to sponsor 5 Japanese delegates who will come to Leicester. |
| Impact | Seminar of Thomas Schalch at the University of Tokyo. The conference has been delayed massively by the Covid-19 pandemic. We managed to organize it very successfully in August 2022,. |
| Start Year | 2019 |
| Description | Colaboration with Hiroshi Kimura and Hitoshi Kurumizaka |
| Organisation | University of Tokyo |
| Country | Japan |
| Sector | Academic/University |
| PI Contribution | We are running the Japan-UK Regulation through Chromatin Conference in Leicester as the main organizers. |
| Collaborator Contribution | Our Japanese organizing partner is Hitoshi Kurumizaka from the University of Tokyo, who contributes time to organize the Japanese delegation. Hiroshi Kimura from the Tokyo Institute of Technology has provided his own grant money to sponsor 5 Japanese delegates who will come to Leicester. |
| Impact | Seminar of Thomas Schalch at the University of Tokyo. The conference has been delayed massively by the Covid-19 pandemic. We managed to organize it very successfully in August 2022,. |
| Start Year | 2019 |
| Description | Daniel Panne |
| Organisation | University of Leicester |
| Department | Department of Molecular and Cell Biology |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Our two laboratories are collaborating on understanding chromatin behaviour upon acetylation of histones. We are providing chromatin material and expertise. |
| Collaborator Contribution | The Panne lab is providing materials and expertise for histone acetylation. |
| Impact | None so far. Manuscript is in preparation. |
| Start Year | 2021 |
| Description | Jun-ichi Nakayama |
| Organisation | Ministry of the Environment |
| Department | National Institute for Basic Biology (NIBB) |
| Country | Japan |
| Sector | Public |
| PI Contribution | We are collaborating on understanding the regulation of the H3K9 methyltransferase Clr4 in heterochromatin formation. |
| Collaborator Contribution | JN has provided us with vital biochemical information that we are now pursuing using structural approaches. |
| Impact | No outputs yet. |
| Start Year | 2022 |
| Title | Conference Website |
| Description | Website based on Wordpress for conference information. The website also integrates the OpenConf registration system. It was developed by Thomas Schalch and runs on the University of Leicester infrastructure. |
| Type Of Technology | Webtool/Application |
| Year Produced | 2020 |
| Open Source License? | Yes |
| Impact | This conference website is critical for realizing the conference and the UK-Japan knowledge exchange. |
| URL | https://chromatin2020.le.ac.uk/ |
| Description | Abstracts booklet Japan-UK Regulation through Chromatin Conference 2022 |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Conference booklet containing abstracts and other helpful information about the conference for the participants and University. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://chromatin2022.le.ac.uk/wp-content/uploads/2023/03/Abstracts_JP-UK_Chromatin-1.pdf |
| Description | Conference Website |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Conference website that provides information and promotes the core activity of this grant, which is the organization of the UK-Japan partnering conference. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://chromatin2022.le.ac.uk |
| Description | Global Discussion Camp, Tokyo Metropolitan University |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Undergraduate students |
| Results and Impact | Thomas Schalch was part of a delegation from the University of Leicester with undergraduate students and colleagues, which visited Tokyo Metropolitan University (TMU) for a week-long workshop with TMU undergraduate students and professors. Thomas gave a lecture covering topics of the BBSRC grants. This activity sparked many new contacts and will likely lead to further exchanges between TMU and the Univeristy of Leicester. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Seminar Thomas Schalch The University of Tokyo |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Thomas Schalch presented a research seminar at the University of Tokyo hosted by Hitoshi Kurumizaka. During this meeting, Thomas Schalch met with various researchers and faculty from other Japanese Universities. This visit also further consolidated the collaboration of Thomas Schalch with Hitoshi Kurumizaka on the Chromatin conference we are organizing in Leicester, which is supported by our BBSRC Japan Partnering Award. The visit further provided an opportunity to explore opportunities for future collaborations. |
| Year(s) Of Engagement Activity | 2019 |