FARMS-SAFE: Future-proofing Antibacterial resistance Risk Management Surveillance and Stewardship in the Argentinian Farming Environment

Lead Research Organisation: University of Bristol
Department Name: Clinical Veterinary Science

Abstract

Antibacterial drug resistance (ABR) is a global threat to health and development and a problem that is getting steadily
worse. Within Latin America, Argentina has been tracking levels of ABR in human infections since 1986. Argentina was
also the first country in the region to develop a national strategy for the control of ABR. This national Strategy takes a
starting assumption that the use of antibacterial drugs (ABs) in livestock agriculture is in part responsible for the threat
of ABR in humans. The use of ABs on farms can potentially result in ABR human infections via 3 main pathways: (1)
ABR bacteria selected in the farm environment infect humans, or at least the mobile ABR genes carried within them
are transmitted to bacteria that infect humans; (2) Agricultural AB residues in food are ingested by humans, selecting
for ABR in human bacteria; (3) Agricultural ABs contaminate the non-farm environment, selecting ABR in bacteria
there, which then infect humans. In Argentina, data are extremely limited for the amount of ABR bacteria on farms
and in the near-farm environment. Furthermore, whilst AB residues are monitored in foodstuffs entering the formal
market, there is a significant informal market, and AB levels in the environment are not routinely measured. One
potential response to the rising threat of ABR is regulation, and both international organizations - led by the WHO -
and individual countries have sought to formulate, for example, new regulatory frameworks to address the and use of
ABs in farming, as well as the management of farm waste. As the O'Neill report recognises, however, developing
countries "...will need extra support and additional time to train veterinarians, develop regulations, build surveillance
capacity and improve farming practices". The premise of this project - FARMS-SAFE - is that as well as providing better
surveillance information for ABR and AB usage, extra support for Argentina and other Latin American countries should
encompass a risk-based approach to the design of regulation as well as to the strengthening of enforcement capacities;
their weakness is another source of risk.

FARMS-SAFE will address this issue by reference to four key risk areas via an UK/Argentinian research consortium:

1. Animal disease as a driver of ABR risk - We will identify why farmers use ABs in the context of animal disease.

2. Animal husbandry practice as a driver of ABR risk - We will identify what farm management practices are being
employed that influence the usage of ABs and will perform surveillance of the usage of ABs on farms in Argentina.

3. Farm waste management as a driver of ABR risk. We will perform surveillance of ABR bacteria with clear
potential to affect human health on farms in the near farm environment and will measure the levels of ABs and
other chemicals in the near-farm environment. We will correlate ABR with AB usage and will identify management risk
factors for ABR and AB contamination in the environment.

4. Regulatory capacity as a driver of ABR risk. We will identify the key individuals and organisations involved in
regulation of ABR and work with them to develop tools that can be used to regulate in a way that is informed by the
risks that drive ABR.

This work will lead to significant new understanding of the prevalence and causes of ABR in Argentinian farming
systems, how this influences the near-farm environment (and so potentially influences human health) and will inform
policy making within Argentina, Latin America and the wider world. We will also create a surveillance structure and
trained researchers who can continue to monitor ABR, AB usage and environmental contamination with ABs and ABR
into the future, and who can measure success and failure of strategies employed to reduce this risk.

Technical Summary

WS1: We will design and implement a nationwide telephone survey administered to farms. We will explore respondents' views about ABR, what ABs are being used on farms, how they are sourced, what diseases they are used to prevent or treat and how farmers view their use. A combination of qualitative and quantitative analyses will be used to examine differences in reported farmer perceptions and behaviours according to predictor variables.

WS2: We will undertake an in-depth social science analysis of how farmers deal with animal health, ABs and the risk of ABR. In-depth semi-structured interviews, ethnographic farms visits and participant observation at agro-shops will be used. Qualitative data will be thematically analysed using Quirkos qualitative text analysis software.

WS3: We will develop survey methodologies for AB, metal and biocide use using veterinary prescription and on-farm records, validated using bin audits. Evaluation of farm risk factors associated with ABU will be carried out using multilevel, multivariable regression modelling with variables identified in WSs 1 and 2.

WS4: We will establish surveillance protocols for ABR bacteria on farms. We will monitor prevalence and mechanism of ABR in Enterococci, Escherichia coli, Salmonella and Campylobacter using whole genome sequencing to link bacteria and ABR mechanisms between and within farms and near-farm environments. We will measure AB, metal and biocide contamination on farms and in near-farm environments and associate this with on-farm ABU, ABR and management practices using multilevel, multivariable linear regression modelling.

WS5: We will map regulatory actors for ABU and ABR, developing a heuristic model to summarise the major ABR risk factors for each livestock sector identified in WS1-4 in ways that are clear, understandable and actionable by regulators. We will produce policy briefing and best practice position papers to be shared with stakeholders in Argentina and the region.

Planned Impact

Health and welfare of Argentinian people and animals, along with those across Latin America
There is a significant burden of disease and economic cost of antibacterial drug resistance (ABR) in Argentina. Since
ABR is rising, inevitably the health and well-being cost of ABR will also rise, and probably moreso in developing areas
like those of Latin America, which are likely to have higher death tolls (of both humans and animals) than other regions.
Our aim is to develop an holistic picture of ABU and ABR in livestock systems in Argentina and to uncover their impact
on the environment as well as to identify potential interventions that can reduce ABU and so ABR. What we learn will
be transferable to other countries, particularly neighbouring countries in Latin America where ABR is also a significant
burden. In order to meet this challenge and improve human health, we need to have impact in policy engagement as
well as public engagement at all levels - from our study site to the entire Latin American region. One major advantage
of the timing of our proposed work is that it is contemporaneous with the implementation and review of Argentina's
Strategy to Control ABR, which is specifically focussed on reducing ABU and ABR in humans and animals. Our work will
synergise and expand current surveillance work ongoing in Argentina, and this synthesis will be extremely valuable
both in benchmarking success and informing modification of the Strategy for Argentina and her neighbours.

Policy makers and other stakeholders in Argentina and Latin America
Our project will provide timely information on key actions and resolutions for better control and traceability of ABs in
livestock farming and will identify the realities of compliance in these areas in ways that policy makers are currently
unable to fully assess. Findings of our study will be developed into policy briefings and disseminated through our
excellent policy partners and links in Argentina and throughout Latin America, impacting policy in the region directly.
Our work will also be presented at sub-national meetings within Argentina and meetings across Latin America as well
as internationally so that it can be applied to developing policy concurrently and subsequent to the work being
completed.

Industry (farming and veterinary)
Overuse of ABs, biocides and metals in Argentinian agriculture may reduce the economic efficiency of the agricultural
industries. Better farm management practices would not only reduce the reliance on medicines and chemicals, but
would improve yields in livestock agriculture, thereby improving overall economic growth. The risk factor analysis in
this project - combined with social science work - will uncover farm management practices and potential leverage
points that can be used to encourage more efficient practices across livestock agriculture. Many of these will reduce
ABR but all will lead to more responsible use of ABs. This project also addresses the impact that the farming industries
and veterinary profession might have on human health through animal-mediated contamination of publicly accessible
land and waterways with ABR bacteria. Understanding risk factors for acquisition of ABR in livestock and possible ways
to mitigate these will assist the livestock industries as they react to growing public concern about ABR and possible
legislation in an informed way. Directly involving stakeholders from these sectors in our project will allow them to
advocate for our findings in their own industries. For example, provision of first-hand evidence on the positive effect
of reducing ABU on ABR levels on the farms in our study may stimulate a peer-led process to encourage others to
reduce levels further. Limiting the rise of ABR will make farming in Argentina productive (via less untreatable disease)
and more economically successful, and will provide a model for tackling ABR elsewhere in the world.

Publications

10 25 50
 
Description Designing the data collection tools has already improved communication between researchers from different institutions as well as a government partner. There is improved recognition of the problem of inappropriate use of antimicrobials as well as antimicrobial resistance by the veterinarians and producers with which our project has engaged in Argentina. Work has been delayed by the pandemic and lockdown in Argentina but we have been making excellent progress in the meantime and have designed an excellent Communications and Impact Strategy that has already been publicised to other projects and stakeholders.
Exploitation Route From the outset, this research has worked closely with the veterinary profession, dairy industry and pig industries in Argentina as well as the government agency, SENASA. The insights from the various empirical components of the research will be actively discussed with members of the farming sectors and veterinary profession as the research progresses. More specifically, the project will provide policy insights into better ways to manage and measure antimicrobial use as well as to prevent AMR. In providing a Vade Mecum for the antibiotics used in these livestock sectors in Argentina, we anticipate management of use of these important medicines will be improved throughout Argentina. It is our hope that the outcomes of this funding will be taken forward by policy makers, the veterinary profession and livestock farmers to improve management of AMR worldwide, but especially in Latin America.
Sectors Agriculture, Food and Drink,Education,Environment,Healthcare,Government, Democracy and Justice,Pharmaceuticals and Medical Biotechnology,Retail

 
Description Ongoing research undertaken as part of the FARMS-SAFE project is currently informing producers and veterinarians about the issues of antimicrobial stewardship and resistance in the Argentinian context. Our researchers have engaged with a number of farmers and farmer groups in the areas in which the research will be undertaken and are raising awareness of AMR in these communities.
First Year Of Impact 2020
Sector Agriculture, Food and Drink,Education
Impact Types Cultural,Societal

 
Description CONICET Argentina - Internal Doctoral Scholarships. Antibiotic residues and AMR in replacement veal (E. coli and S. aureus). Doctoral thesis, UNLP
Amount $1,090,320 (ARS)
Organisation National Scientific and Technical Research Council (Argentina) 
Sector Public
Country Argentina
Start 04/2021 
End 04/2023
 
Description CONICET Argentina - Internal Doctoral Scholarships. Artificial rearing of calves. Doctoral thesis, UNLP
Amount $1,090,320 (ARS)
Organisation National Scientific and Technical Research Council (Argentina) 
Sector Public
Country Argentina
Start 04/2021 
End 04/2023
 
Description CONICET Doctoral Scholarships Fund - Metritis. Postdoctoral plan by the Faculty of Veterinary Sciences, UNLP
Amount $3,289,980 (ARS)
Organisation National Scientific and Technical Research Council (Argentina) 
Sector Public
Country Argentina
Start 04/2021 
End 04/2026
 
Title Standard Operating Procedures (SOPs) for microbiology sampling & data collection 
Description A data & sample collection SOP was designed in a participatory meeting during the Capacity Building Workshop in La Plata in February 2020. PI's, CoI's and Post Graduate Researchers from UoB, UNLP and UNRC jointly drafted a document with the methodological approach for data and sample collection and transportation to the labs. Research Teams for milking parlors and pig farms have been defined in both La Plata and Rio Cuarto in order to conduct the microbiological and molecular anaylisis for WS3. 
Type Of Material Biological samples 
Year Produced 2020 
Provided To Others? No  
Impact The capacity building workshop in La Plata aimed to ground our project's methodological proposal in the Argentinian context. Therefore, this outcome resulted from mulitidisciplinary work that harmonised a methodological approach for collection of epidemiologic data and bacteriologic samples. The meeting opened a discussion space between the team for further defining research standards for sample and data collection within these workstreams of the project. A document with a methodological approach for sampling and data collection has been agreed and validated among the team directly contributing to strengthen research capacities and knowledge exchange. 
 
Description Collaboration with Nora Mestorino, University of La Plata 
Organisation University of La Plata
Country Argentina 
Sector Academic/University 
PI Contribution We have developed a collaboration to test AMR in bacteria from farms in Argentina, which will be isolated by Dr Mestorino, and analysed by us. This has also resulted in a BBSRC grant, funded to extend this work from the preliminary.
Collaborator Contribution They have provided bacterial isolates for our analysis
Impact BBSRC grant awarded.
Start Year 2019
 
Description 74th Association for Veterinary Teaching and Research Workers Annual Conference, Glasgow 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact The Project Manager presented the FARMS-SAFE project in a presentation entitled 'Impact and engagement: communicating research in a multi-cultural and multi-disciplinary environment'. From our experience in Argentina, he presented an interesting approach on how the research has been developed not just to ground and introduce the research, but also to tailor our communication strategy within the Argentinian context. It was important for us present this work to the veterinary practitioner, teaching and research community in the UK in order to share our experience with multi-cultural research and sharing ideas strengthening the sustainability of the project in the short- and mid-term in this context.
Year(s) Of Engagement Activity 2020
URL http://www.avtrw.co.uk/files/5315/9964/3968/AVTRW_Conference_2020_Programme.pdf
 
Description AMR Force (Reyher) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Exploration of collaboration opportunities with VMD, Langford
Year(s) Of Engagement Activity 2019,2020
 
Description Agriculture and Horticulture Development Board Mastitis Control Plan Management Group meeting (Reyher) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Mastitis Control Plan Management Group Committee meeting in Wells
Year(s) Of Engagement Activity 2019
 
Description Bristol AMR/Colston Research Symposium. The Antibiotic Age: The End or a New Beginning? 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact Gave a speech entitled: 'Antibiotics Anonymous - Antimicrobial stewardship and voluntary reduction across the UK livestock sectors' and networked with conference attendees
Year(s) Of Engagement Activity 2019
URL https://www.bristol.ac.uk/amr/events/2019/colston-research-society-symposium.html
 
Description Bristol, North Somerset, South Gloucestershire CCG, One Health AMR meeting (Reyher) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact Meeting of the Bristol, North Somerset, South Gloucestershire Clincial Commissioning Group One Health AMR meeting at Bristol Royal Infirmary
Year(s) Of Engagement Activity 2019
 
Description CHAWG AMU Steering group (Reyher) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Cattle Health and Welfare Group, Antimicrobial Use Group steering group committee meeting in London
Year(s) Of Engagement Activity 2019
 
Description Capacity Building Workshop for FARMS-SAFE research group 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact The Capacity Building Workshop held at the UNLP Faculty of Veterinary Medicine from 3rd to 7th February 2020 brought all the project teams together for discussions with the intention of working out detailed plans for delivery of the research. This workshop allowed improved learning about farming systems and the data that exist in Argentina, especially in La Plata and Cordoba. By adopting a participatory approach, SOPs were designed to allow for data and sample collection including: i) providing ideas for the national survey and research tools for WS1 and WS2, ii) designing SOPs for ABU and ABR for WS3, iv) discussing ABR and antibiotic/chemical contamination for WS4, and v) developing a risk-based approach to targeting ABR for WS5. Examining workflow and capacity as well as considering the other projects funded under this call and possible species overlap along with risks from livestock species to ABR meant that the project was re-focussed on the dairy and pig industries. During the workshop, farm visits were organised for both the UK and Argentine colleagues to interview and participatorily observe and analyse the different farming practices on dairy and pig farms around La Plata.
Year(s) Of Engagement Activity 2020
 
Description Capacity Building Workshop for FARMS-SAFE research group 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Postgraduate students
Results and Impact The Capacity Building Workshop was held at the Faculty of Veterinary Medicine of University of La Plata from 3rd to 7th February 2020. The workshop was facilitated by the UK & Argentine PIs and CoIs to learn more about farm systems and the data that exists in Argentina, especially in La Plata and Cordoba.
By adopting a participatory approach SOPs were designed for data and sample collection for: i) drafting a national survey & tools for WS1 and WS2, ii) AMU and AMR for WS3, iv) AMR and AM/chemical contamination for WS4 and v) developing a risk-based approach to targeting AMR for WS5. National Autorities from SENASA, academics and postgraduate students from UNLP and Rio Cuarto as well as the team from UoB participated in the meeting.
During the workshop farm visits were organised for both the UK and Argentine colleagues to interview and participatorily observe and analyse the different farming practices among dairy and pig farms around La Plata.
Year(s) Of Engagement Activity 2020
 
Description Cattle Health and Welfare AMU Steering Group (Reyher) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact committee meeting of the steering group on Cattle Health and Welfare at Stoneleigh
Year(s) Of Engagement Activity 2019
 
Description Cattle Health and Welfare Group AMR Steering Group, UK 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact Online meetings held on 4/28/2021 and 7/16/2020 to discuss antimicrobial use and measurement in the cattle sectors - metrics for antimicrobial use have been developed and uptaken across the UK cattle industries
Year(s) Of Engagement Activity 2020,2021
 
Description Feature article on AMR on the Times Higher Education 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Article showcasing the research work at the University of Bristol, where researchers from numerous disciplines are working together to understand and control AMR in an effort to save lives at home and abroad.
Year(s) Of Engagement Activity 2020
URL https://www.timeshighereducation.com/hub/university-bristol/p/taking-fight-superbugs
 
Description Food Industry Initiative on Antimicrobials Research & Development Committee + Data Committee - Quarterly Meeting (Reyher) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Quarterly committee meeting of the Food Industry Initiative on Antimicrobials Research & Development Committee + Data Committee
Year(s) Of Engagement Activity 2019
 
Description Gloucestershire Antimicrobial Stewardship Group, UK 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Industry/Business
Results and Impact Working with medical and dental practitioners in a One Health context to better understand antimicrobial stewardship and resistance; Online meeting of shared working held on 18/06/2020.
Year(s) Of Engagement Activity 2020
 
Description Gloucestershire One Health AMR group (Reyher) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact Prepared communication plan for Gloucestershire on One Health AMR
Year(s) Of Engagement Activity 2019
 
Description Grant Launch Workshop - UK & Argentina AMR in the environment 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Study participants or study members
Results and Impact The Grant Launch Workshop was organised by BBSRC & CONICET. Five projects funded through DoHSC/UKAid (along with BBSRC & NERC) in the UK and CONICET in Argentina presented their workpackages in order to create a collective proposal to develop a Pan-Program Intregration Project (PPIP) and policy translation activities within the Argentine context. A draft PPIP document was gathered from the workshop aiming to:

- Aim 1 Combine expertise and data from all five project teams to provide consistency to (i) the co-design of policy with agricultural livestock sectors (ii) the measurement of antimicriobial use (AMU) and resistance (AMR), and (iii) knowledge exchange messages across all the livestock species and production systems encompassed by the program.
- Aim 2 "A whole that is greater than the sum of its parts" - to generate research outcomes at the level of the program that would not be possible for any one project alone through combining effort and new work in specifically defined areas.

The aims will be addressed through four work packages. UoB through the FARMS-SAFE project leads Work Package 1 (WP1) - Harmonising antimicrobial use and data collection.
Year(s) Of Engagement Activity 2019
URL https://bbsrc.ukri.org/news/events/2018/1806-argentina-antimicrobial-resistance/
 
Description Host Head of Population Health and Head of Research, Ontario Veterinary College, Guelph University, Ontario, Canada 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Discuss AMR research and possible overlaps in collaborations
Year(s) Of Engagement Activity 2019
 
Description Initial engagement w/ Pan-American Center for Foot and Mouth Disease and Veterinary Public Health, PANAFTOSA-PAHO/WHO 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact The project had an initial engagement with the Food Safety Specialist of the Pan-American Center for Foot and Mouth Disease and Veterinary Public Health at PAHO. It is intended to work closely to boost the AMR information in Argentina jointly with SENASA across the Americas.
Year(s) Of Engagement Activity 2020
 
Description International Antibiotic Usage Forum (Reyher) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Collaborative catch-up with AMR groups around the world - collaborations and contributions to practice
Year(s) Of Engagement Activity 2019
 
Description Interview for BBC Points West 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Discussed AMR research at the Bristol Veterinary School on 14th November 2019.
Year(s) Of Engagement Activity 2019
 
Description Interview with FAIRR re: AMR in livestock 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Interview on 25/09/20 - informed evidence gathering for use in advising a global network of investors - fed into international webinar regarding antimicrobial stewardship by companies
Year(s) Of Engagement Activity 2020
 
Description Keynote presentation at 'A Celebration of One Health: Collaborative Cultures' 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Collaborative Cultures explores the impact of a One Health approach. Working, learning and sharing best-practice across disciplines. In September 2019 ACTAsia launched its Institute of Caring for Life Academic Research & Education (iCARE) at Oxford University, at a meeting called 'Health & Well-being: Science and Humanity are One'. As a follow-up to this event and to discuss the progress made, we are holding a webinar on One Health Day, 3 Nov 2020. Fast-forward to this webinar, we will celebrate a One Health interdisciplinary approach to the challenges faced for humans, animals and the environment. The discussions are especially poignant in 2020 as many academics and professionals are shifting their thinking to incorporate all three areas into their research and solutions to ensure maximum impact. The Webinar will close with a Charter for Collaborative Cultures being drawn up for iCARE projects. Speakers: Dr. Laura Kahn, Professor Terence Ryan, Professor Adam Hart, Dr. Kristen Rehyer, Sarah Gould and Dr Helen Winter.
Year(s) Of Engagement Activity 2020
URL https://onehealthplatform.com/content/celebration-one-health-collaborative-cultures
 
Description MOOC, Creating course on antimicrobial stewardship for vets (Reyher) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Discussion about AMR Massive Open Online Course phone meeting re training of practitioners and professionals
Year(s) Of Engagement Activity 2019
 
Description Massive open online course - contribution 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Massive Open Online Course on Antimicrobial Stewardship for Veterinarians - Kristen Reyher contributed to a conversation about antimicrobial stewardship that forms part of this course which has so far reached and changed the views and behaviours over 4000 learners from more than 120 countries.
Year(s) Of Engagement Activity 2020
URL https://www.futurelearn.com/courses/antimicrobial-stewardship-in-veterinary-practice
 
Description Mastitis Research Workers Conference, US 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Daniel Buldain, PhD student and team member of the FARMS-SAFE project, presented to veterinary practitioners and colleagues at the MRWC on 02/12/2020 which generated interest in the project and research areas such as natural compounds
Year(s) Of Engagement Activity 2020
 
Description Medical Research Foundation AMR PhD student cohort meeting 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact Gave a talk at the training day for PhD students - discussed my background and journey in research and AMR research at Bristol - 15th November 2020.
Year(s) Of Engagement Activity 2019
 
Description Meeting with National Milk Labs (Reyher) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Collaboration with FarmAssist, thinking about AMU metrics. Meeting in Langford
Year(s) Of Engagement Activity 2019
 
Description Meeting with representatives of the Welsh Government 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Phone meeting with Welsh Government to discuss about AMR
Year(s) Of Engagement Activity 2019
 
Description Meetings with National Milk Laboratories, UK 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact Discuss and decide upon FarmAssist software features rolled out to the cattle industries - currently ~35% of the dairy sector has access to this software with >1300 farms from >180 veterinary practices actively using the software to benchmark antimicrobial use. Meetings held on 4/22/2021, 5/18/2020 and 6/24/2020.
Year(s) Of Engagement Activity 2020,2021
URL https://www.nationalmilklaboratories.co.uk/vets/farm-assist
 
Description Phone talk with Channel 4 Dispatches, UK 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Media (as a channel to the public)
Results and Impact Phone conversation with reporter about AMR in the environment - not featured in programme
Year(s) Of Engagement Activity 2020
 
Description Podcast 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Podcast with Royal College of Veterinary Surgeons Trust on AMR with the UK's Chief Veterinary Officer
Year(s) Of Engagement Activity 2019
 
Description Project Presentation for Dairy Producers in La Plata, Buenos Aires Province 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact Engagement and training activities regarding AMR and antimicrobial use with the Board of the Association Pro-quality of Milk (APROCAL) in Argentina.
Year(s) Of Engagement Activity 2020
 
Description Project Presentation for Pig Producers in Buenos Aires Province 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact Engagement and training activities with the Technological Exchange Group of Pig Industry (GITEP) - 40 producers attended
Year(s) Of Engagement Activity 2020
 
Description Project Presentation for Pig Producers in Buenos Aires Province 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact Engagement and training activities about AMR and the FARMS-SAFE with the Group of Technicians and Pig Producers (GTPC) in Buenos Aires
Year(s) Of Engagement Activity 2020
 
Description Project presentation to the research community at University of La Plata 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact Organised by the Faculty of Veterinary Medicine of the University of La Plata, up to 60 Postgraduate students and Senior Researchers attended this talk on:

1.Selection and transmission of AMR in a One Health context, Matthew Avison.
2.Investigating prescription, usage and control of veterinary medicines: methods and insights from a social science approach, Maria Paula Escobar.
3.Strategies to optimize antimicrobial efficacy in veterinary medicine in the context of One Health, Nora Mestorino
4.FARMS-SAFE, an overview of the project, Kristen Reyher
Year(s) Of Engagement Activity 2019
 
Description RCVS Veterinary Antibiotic Champions initiative 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Engaging with industry and charity stakeholders to offer antimicrobial stewardship to veterinary surgeons across the UK. Stakeholder meeting 26/2/21.
Year(s) Of Engagement Activity 2021
 
Description RUMA Independent Scientific Group committee meeting (Reyher) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Responsible Use of medicines in Agriculture Alliance (RUMA) scientific group meeting in London
Year(s) Of Engagement Activity 2019
 
Description Research meeting with representative from Boehringer Ingelheim 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact Research meeting with representative from Boehringer Ingelheim to discuss AMR topics
Year(s) Of Engagement Activity 2019
 
Description Responsible Use of Medicines in Agriculture Alliance (RUMA) Independent Scientific Group meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact RUMA Independent Scientific Group - providing scientific evidence to this industry body made up of stakeholders from across the animal health spheres - meetings in London on 6/4/2020 and 7/3/2020.
Year(s) Of Engagement Activity 2020
 
Description Responsible Use of Medicines in Agriculture Alliance (RUMA) meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact RUMA Cattle Antibiotic Use Targets meeting on 01/09/20 - engaged with industry to encourage reduction of antimicrobials in the cattle sectors
Year(s) Of Engagement Activity 2020
 
Description Responsible use of medicines in Agriculture Alliance (RUMA) Targets Task Force 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Gave an invited talk to challenge livestock industries in AM stewardship targets in Stoneleigh on 10th September 2019
Year(s) Of Engagement Activity 2019
 
Description SENASA / ANLIS - Seminar 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact The seminar "Antimicrobials, One Animal Health and Production" was held at the Laboratory of the National Service of Agrifood Health and Quality (Senasa) in Buenos Aires. Presentations were oriented to the impact of AMR on the environment, animal production, public health and regional economies seeking to highlight the importance of AMR surveillance programs and the way AMR affects national production.

At the end of the event, a discussion table was set up to analyse the perspectives of the different actors working on reducing the impact of AMR and to assess the possible options for a better and coordinated efforts. FARMS-SAFE PI and CoIs attended and contributed to discussions and networking.
Year(s) Of Engagement Activity 2019
 
Description Speak with BBC Radio4 Costing the Earth 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact Phone interview with the BBC Radio4 to discuss AMR research - background information to be used in radio presentation
Year(s) Of Engagement Activity 2020
 
Description Speak with Channel 4 Dispatches 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Phone interview with Channel 4 Dispatches to inform a documentary about food safety
Year(s) Of Engagement Activity 2020
 
Description V RELIM Annual Meeting - "Milk Quality in One Health" 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact The Latin American Mastitis Research Network (RELIM) is a non-profit professional network of milk quality and bovine mastitis control specialists from all the countries of Latin America. This professional network has as a main goal to improve the exchange of knowledge about intramammary infections affecting herds in the various dairy production systems utilized in the member countries, to ultimately produce quality milk by environmentally sustainable standards.
The members of our organization include professionals from the milk production industry and dairy processors, researchers, milk quality consultants, young veterinary students and graduate students. The University of La Plata presented the different strains of the FARMS-SAFE project by showcasing an informative brief during the annual meeting in La Plata between 25th and 28th November 2019.
Year(s) Of Engagement Activity 2019
 
Description Veterinary Schools Council AMR (Reyher) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact phone meeting
Year(s) Of Engagement Activity 2019
 
Description Veterinary Schools Council, AMR (Reyher) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Phone meeting with committee
Year(s) Of Engagement Activity 2019
 
Description Virtual Conference III Edition of the Porcine Enteric Academy, Buenos Aires 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact Dr Nora Mestorino, CoI from Argentina for the FARMS-SAFE project presented during the virtual conference her topic: Antibiotic Use in Swine Production: Where Are We Going? During her presentation, she introduces the FARMS-SAFE project to the III Edition of the Porcine Enteric Academy, Boehringer Ingelheim in Buenos Aires, Argentina.
Year(s) Of Engagement Activity 2020
URL https://www.sudamerica.boehringer-ingelheim.com/salud-animal/animales-de-produccion/tercera-edicion-...
 
Description Webinar training Welsh farm vets on antimicrobial stewardship, UK 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Arwain Vet Cymru Webinar for veterinary practitioners on 14/10/20 - inspired veterinarians to design antimicrobial stewardship interventions in their veterinary practices
Year(s) Of Engagement Activity 2020